Abstract
Conflict of interest (COI) describes a situation in which the impartiality of research may be compromised by the researcher standing to profit in some way from conclusions drawn in the research. This can be a conflict among roles as when a researcher takes on too many outside consulting duties and neglects mentoring students, or misses classroom teaching, or a conflict of trust when the ability to make money from offering a particular interpretation of findings distorts trust in the analysis or conclusions reached. COI can occur at individual, institutional, or industry level or in a particular case, at several of these levels at once. Conflicts can arise from financial, ideological, political, religious beliefs, or personal relationships. Transparency through the disclosure of financial COIs has been the main management technique for handling COI. But it is suboptimal because it provides no way to know for sure whether competing interests have compromised the research (Dunn et al. 2016). There is no detailed federal policy in the USA on identifying or managing institutional conflicts of interest. A survey by Resnik (2016) found that only 38% of top grant getting institutions had such policies.
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References
Campbell E, Bogeli C, Rao S, Abraham M, Pierson R, Applebaum S. Industry relationships among academic institutional review board members; changes from 2005 through 2014. JAMA Intern Med. 2015;175(9):1500–6.
Dunn A, Colera E, Mandl K, Bourgeois F. Conflict of interest disclosure in biomedical research: a review of current practices, biases, and the role of public registries in improving transparency. Res Integr Peer Rev. 2016;1:1.
Elliott C. Institutional pathology and the death of Dan Markingson. Account Res. 2016. Epub ahead of print.
Kearns C, Glantz S, Schmidt L. Sugar industry influence on the scientific agenda of the National Institute of Dental Research’s 1971 National Caries Program: a historical analysis of internal documents. PLoS Med. 2015;12(3):e1001798.
Resnik D. Institutional conflicts of interest policies at U.S. academic research institutions. Acad Med. 2016;91(2):242–6.
Wilson J. Lessons learned from the gene therapy trial for ornithine transcarbamylase deficiency. Mol Genet Metab. 2009;96:151–7.
Additional Suggested Reading
Dunn A, Colera E, Mandl K, Bourgeois F. Conflict of interest disclosure in biomedical research: a review of current practices, biases, and the role of public registries in improving transparency. Res Integr Peer Rev. 2016;1:1. (A public registry of competing interests is needed in order to have a comprehensive view of COI.)
Elliott C. Institutional pathology and the death of Dan Markingson. Account Res. 2016. Epub ahead of print. (Apparent institutional regulatory oversight failure by a major public university is described. 2017 24(2):65–79)
Resnik D. Institutional conflicts of interest policies at U.S. academic research institutions. Acad Med. 2016;91(2):242–246. (Policy development for institutional conflicts of interest are incomplete.)
Yanagawa H. Current regulatory systems for clinical trials in Japan: Still room for improvement. Clin Res Regul Aff. 2014;31(2–4):23–28. (Describes how a country develops its research regulatory system including management of COI.)
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Caplan, A.L., Redman, B.K. (2018). Conflict of Interest. In: Caplan, A., Redman, B. (eds) Getting to Good. Springer, Cham. https://doi.org/10.1007/978-3-319-51358-4_11
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DOI: https://doi.org/10.1007/978-3-319-51358-4_11
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