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Ultrasound-Guided Laser Ablation

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Advanced Thyroid and Parathyroid Ultrasound

Abstract

Surgery is the long-established therapeutic option for benign thyroid nodules which steadily grow and become symptomatic. However, the cost of thyroid surgery and the risk of temporary or permanent complications with not negligible consequences on the quality of life, remain relevant concerns. Therefore, various minimally invasive therapies (MIT), directed toward office-based management of symptomatic nodules, without requiring general anesthesia, and with negligible damage to the skin and cervical critical structures (i.e., epiaortic vessels and the trachea), have been proposed during the last two decades.

Today, among the different image-guided ablative technologies, US-guided laser thermal ablation (LA) has been thoroughly evaluated and is an accessible procedure in specialized centers. In solid nonfunctioning thyroid nodules that grow or become symptomatic, this technique results in a volume decrease of up to 85 % and improvement in local symptoms. LA may be also effective in treating small hyperfunctioning nodules, but multiple LA sessions are required to normalize TSH levels in large nodules.

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Authors and Affiliations

  1. Department of Diagnostic Imaging and Interventional Radiology, Regina Apostolorum Hospital, Via San Francesco, 50, Albano Laziale, Rome, 00041, Italy

    Claudio Maurizio Pacella M.D.

  2. Department of Endocrinology and Metabolism, Regina Apostolorum Hospital, Albano Laziale, Rome, Italy

    Enrico Papini

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  1. Claudio Maurizio Pacella M.D.
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Correspondence to Claudio Maurizio Pacella M.D. .

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Editors and Affiliations

  1. Department of Surgery and the Endocrinology & Metabolism Institute, University of Arizona College of Medicine - Phoenix, Banner - University Medical Center Phoenix, Phoenix, Arizona, USA

    Mira Milas

  2. Department of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Susan J. Mandel

  3. Department of Radiology, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Jill E. Langer

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Pacella, C.M., Papini, E. (2017). Ultrasound-Guided Laser Ablation. In: Milas, M., Mandel, S.J., Langer, J.E. (eds) Advanced Thyroid and Parathyroid Ultrasound. Springer, Cham. https://doi.org/10.1007/978-3-319-44100-9_37

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