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Meningioma

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Adult CNS Radiation Oncology

Abstract

Meningiomas are the most prevalent primary intracranial neoplasm. To date, the main management options are observation, surgical resection, and radiation therapy. The choice of treatment depends on symptoms, size, extent of resection, grade of meningioma, and prior treatment. Although the majority of meningiomas are benign, Grade II and Grade III meningiomas have a higher risk of recurrence and morbidity. The role of radiation had been based largely on retrospective studies, but four contemporary prospective studies, EORTC 22042-26042, RTOG 0539, NRG BN003, and the ROAM/EORTC1308 trials will define its use, especially in Grade II gross totally resected meningiomas. The role of systemic therapy is limited, but studies are ongoing and necessary. This chapter will review its epidemiology, histology, grade, treatment, and studies, both historical and recent.

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Authors and Affiliations

  1. Department of Radiation Oncology, Virginia Commonwealth University, Richmond, VA, USA

    Timothy J. Harris

  2. Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA

    Samuel T. Chao

  3. Rose Ella Burkhardt Brain Tumor and Neuro-oncology Center, Cleveland Clinic, Cleveland, OH, USA

    Samuel T. Chao

  4. Department of Radiation Oncology, Barrow Neurological Institute, Phoenix, AZ, USA

    C. Leland Rogers

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  1. Timothy J. Harris
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  2. Samuel T. Chao
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  3. C. Leland Rogers
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Editors and Affiliations

  1. Department of Radiation Oncology, Keck School of Medicine of USC, Norris Cancer Hospital, Los Angeles, California, USA

    Eric L. Chang

  2. Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA

    Paul D. Brown

  3. Department of Radiation Oncology, University of Washington Medical Center, Seattle, Washington, USA

    Simon S. Lo

  4. Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

    Arjun Sahgal

  5. Department of Radiation Oncology, Taussig Cancer Institute Cleveland Clinic, Cleveland, Ohio, USA

    John H. Suh

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Harris, T.J., Chao, S.T., Rogers, C.L. (2018). Meningioma. In: Chang, E., Brown, P., Lo, S., Sahgal, A., Suh, J. (eds) Adult CNS Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-42878-9_1

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