Abstract
Renal malformations represent the most common manifestation of congenital diseases in childhood. Renal agenesis, dysplasia, hypoplasia, and cystic renal diseases are such entities. Causes vary; partially they derive from the complex renal organogenesis, and partially they have a genetic background. Today there is evidence that disturbances of the cilium-centrosome complex form the pathogenetic base of most or many phenotypically different cystic renal diseases on a cellular level; thus, they are summarized under the term “ciliopathies” (Guay-Woodford 2006; Hildebrandt 2005; Hildebrandt et al. 2011). Furthermore, uromodulin – a urinary mucoprotein former known as “Tamm-Horsfall protein” – appears to play an important role in the genesis of cystic kidney diseases (Iorember and Vehaskari 2014). The knowledge of the individual etiology and development helps to understand the disease process, affects further diagnostic and therapeutic management, and helps to properly estimate prognosis of these patients and their families, respectively. The clinical and genetic basics including the relevant queries toward imaging are discussed in chapters “Genetics in Nephrourology” and “Renal Agenesis, Dysplasia, Hypoplasia, and Cystic Diseases of the Kidney”.
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References
Alvares F, Bernhard O, Brunelle F (1981) Congenital hepatic fibrosis in children. J Pediatr 99:370–375
Arant BS Jr, Soteol-Avila C, Bernstein J (1979) Segmental “hypoplasia” of the kidney (Ask-Upmark). J Pediatr 95:931–939
Avner ED (1994) Medullary cystic disease and medullary sponge kidney. In: Greenberg A (ed) NFK nephrology primer. Saunders, Philadelphia, pp 174–181
Avni EF, Thova Y, Van Gansbeke G et al (1985) The development of hypodysplastic kidney: contribution of antenatal ultrasound. Radiology 154:123–126
Avni EF, Thoua Y, Laimand B et al (1986) Multicystic dysplastic kidney: evolving concepts. In utero diagnosis and post-natal follow-up by ultrasound. Ann Radiol 29:663–668
Avni F, Matos C, Rypens F, Schulman CC (1997) Ectopic vaginal insertion of an upper pole ureter: demonstration by special sequences of magnetic resonance imaging. J Urol 158:1931–1932
Avni EF, Garel L, Cassart M et al (2006) Perinatal assessment of hereditary cystic renal diseases: the role of sonography. Pediatr Radiol 36:405–415
Avni EF, Hall M (2010) Renal cystic diseases: new concepts. Pediatr Radiol 40:939–946
Avni FE, Garel C, Cassart M, D’Haene N, Hall M, Riccabona M (2012) Imaging and classification of congenital cystic renal diseases. AJR Am J Roentgenol 198:1004–1013
Babut JM, Bawab F, Jouan H et al (1993) Cystic renal tumours in children–a diagnostic challenge. Eur J Pediatr Surg 3:157–160
Baert L, Steg A (1977) On the pathogenesis of simple renal cysts in the adult. Urol Res 5:103–108
Beomonte-Zobel B, Vicentini C, Masciocchi C et al (1990) Magnetic resonance imaging in the localization of undescended abdominal testes. Eur Urol 17:145–148
Bernstein J (1971) The morphogenesis of renal parenchymal maldevelopment (renal dysplasia). Pediatr Clin North Am 18:395–407
Bernstein J (1973) The classification of renal cysts. Nephron 11:91–100
Bernstein J (1976) A classification of renal cysts. In: Gardner KD Jr (ed) Cystic diseases of the kidney. Wiley, New York, pp 7–30
Bernstein J (1992) Renal hypoplasia and dysplasia. In: Edelman CM (ed) Pediatric kidney disease. Little & Brown, Boston, pp 1121–1137
Bernstein J (1993a) Renal cystic disease in the tuberous sclerosis complex. Pediatr Nephrol 7:490–495
Bernstein J (1993b) Glomerulocystic kidney disease-nosological considerations. Pediatr Nephrol 7:464–470
Bisaglia M, Ca G, Senger C, Stallone C, Sessa A (2006) Renal cystic diseases: a review. Adv Anat Pathol 13:26–56
Blowey DL, Querfeld U, Geary D et al (1996) Ultrasound findings in juvenile nephronophthisis. Pediatr Nephrol 10:22–24
Boal DK, Teele R (1980) Sonography of infantile polycystic kidney disease. AJR Am J Roentgenol 135:575–580
Boichis H, Passwell J, David R et al (1973) Congenital hepatic fibrosis and nephronophthisis. Q J Med 42:221–233
Borthne A, Nordshus T, Reiseter T et al (1999) MR urography: the future gold standard in pediatric urogenital imaging. Pediatr Radiol 29:694–701
Bosniak MA (1986) The current radiological approach to renal cysts. Radiology 158:1–10
Bosniak MA (1991) Difficulties in classifying cystic lesions of the kidney. Urol Radiol 13:91–93
Bretan PN Jr, Bush MP, Hricak H et al (1986) Chronic renal failure: A significant risk factor in the development of acquired renal cysts and renal cell carcinoma. Case report and review of the literature. Cancer 57:1871–1879
Brook-Carter PT, Peral B, Ward CJ et al (1994) Deletion of TSC2 and PDK1 genes associated with severe infantile polycystic kidney disease – A contiguous gene syndrome. Nat Genet 8:328–332
Cain JE, Di Giovanni V, Smeeton J et al (2010) Genetics of renal hypoplasia: insights into the mechanisms controlling nephron endowment. Pediatr Res 68:91–98
Churchill E, Kimoff R, Pinshy M et al (1975) Solitary intrarenal cyst: correctable cause of hypertension. Urology 6:485–488
Churg J, Bernstein J, Risdon RA et al (1987) Renal disease. Classification and atlas. Part II: developmental and hereditary disease. Igaku-Shoin, New York
Cohen HL, Haller JO (1987) Diagnostic sonography of the fetal genitourinary tract. Urol Radiol 9:88–98
Cole BR, Wonley SB, Stapelton FB (1987) Infantile polycystic disease in the first year of life. J Pediatr 11:693–699
Cope JR, Trickey FD (1982) Congenital absence of the kidney: problems in diagnosis and management. J Urol 127:10–12
Davidson AJ, Hartman DS (1994) Radiologic anatomy of the kidney and the ureter. In: Davidson AJ, Hartman DS (eds) Radiology of the urinary tract. Saunders, Philadelphia, pp 53–96
deBruyn R, Gordon I (2000) Imaging in cystic renal disease. Arch Dis Child 83:401–407
Devine C (1983) Embryologie des Urogenitaltraktes. In: Hohenfellner R, Zing EJ (eds) Urologie in Klinik und Praxis. Thieme, Stuttgart, pp 833–849
Diard F, LeDosseur P, Cadier L et al (1984) Multicystic dysplasia of the upper component of the complete duplex kidney. Pediatr Radiol 14:310–313
Dinkel E, Ertel M, Dittrich M et al (1985) Kidney size in childhood: sonographical growth charts for kidney length and volume. Pediatr Radiol 15:38–43
Dodat H, Galifer RB, Montupet P et al (1988) Renal tumors in children, excluding Wilm’s tumor. J D Urol 94:67–82
Domizio P, Risdon RA (1991) Cystic renal neoplasms of infancy and childhood: a light microscopical lectin histochemical and immunohistochemical study. Histopathology 19:199–209
Donaldson MDC, Warner AA, Trompeter RS et al (1985) Familial juvenile nephronophthisis, Jeune’s syndrome, and associated disorders. Arch Dis Child 60:426–443
Dunill MS, Millard PR, Oliver D (1977) Acquired cystic disease of the kidneys: a hazard of long term intermittent maintenance haemodialysis. J Clin Pathol 30:868–877
Elzouki AY, al-Suhaibani H, Mirza K et al (1996) Thin-section computed tomography scans detect medullary cysts in patients believed to have juvenile nephronophthisis. Am J Kidney Dis 27:216–219
Estroff JA, Mandell J, Benacerraf BR (1991) Increased renal parenchymal echogenicity in the fetus: Importance and clinical outcome. Radiology 181:135–139
Fabris A, Antonio Lupo A, Ferraro PM et al (2013) Familial clustering of medullary sponge kidney is autosomal dominant with reduced penetrance and variable expressivity. Kidney Int 83:272–277
Fick GM, Johnson AM, Strain JD et al (1993) Characteristics of very early onset autosomal dominant polycystic kidney disease. J Am Soc Nephrol 3:1863–1870
Fick GM, Duley IT, Johnson AM et al (1994) The spectrum of autosomal dominant polycystic kidney disease in children. J Am Soc Nephrol 4:1654–1660
Fitch S, Parvey LS, Wiliams J et al (1985) Developmental cystic renal neoplasms in children: Diagnostic imaging characteristics. Comput Radiol 9:149–158
Fitch SJ, Stapleton FB (1986) Ultrasonographic features of glomerulocystic disease in infancy: similarity to infantile polycystic kidney disease. Pediatr Radiol 16:400–402
Fredericks BJ, de-Campo M, Chow CW et al (1989) Glomerulocystic renal disease: ultrasound appearances. Pediatr Radiol 19:184–186
Frohneberg D (1986) Agensie, Hypoplasie und Dysplasie. In: Hohenfellner R, Thüroff JW, Schulte-Wissermann H (eds) Kinderurologie in Klinik und Praxis. Thieme, Stuttgard/New York, pp 236–240
Gadner KD Jr (1967) Juvenile nephronophthisis and renal medullary cystic disease. In: Gadner KD Jr (ed) Cystic diseases of the kidney. Wiley, New York
Garel LA, Habib R, Pariente D et al (1984) Juvenile nephronophthisis: sonographic appearance in children with severe uremia. Radiology 151:93–95
Guay-Woodford LM (2006) Renal cystic diseases: diverse phenotypes converge on the cilium/centrosome complex. Pediatr Neprol 21:1369–1376
Gelet A, Sanseverino R, Martin X et al (1990) Percutaneous treatment of benign renal cysts. Eur Urol 18:248–252
Glassberg KL, Stephens FD, Lebowitz RL et al (1987) Renal dysgenesis and cystic disease of the kidney: a report on terminology, nomenclature, and classification. Section of urology, American Academy Of Pediatrics. J Urol 138:1085–1092
Gordon AC, Thomas DFM, Arthur RJ et al (1988) Multicystic kidney–is nephrectomy still appropriate? J Urol 140:1231–1234
Greene LF, Feinzwig W, Dahlin D (1971) Multicystic dysplasia with special reference to the contralateral kidney. J Urol 105:482–487
Griscom NT, Vawter GF, Fellers FX (1975) Pelvoinfundibular atresia: the usual form of multicystic kidney: 44 unilateral and 2 bilateral cases. Semin Roentgenol 10:125–131
Hallmann N, Hjelt L, Ahvenainen EK (1956) Nephrotic syndrome in newborn and young infants. Ann Pediatr Fenn 2:227–241
Hattery R, King BF (1995) Technique and application of MR urography. Radiology 194:25–27
Helin I, Persson PH (1986) Prenatal diagnosis of urinary tract abnormalities by ultrasound. Pediatrics 78:879–883
Hendry PJ, Hendry GMA (1991) Observations on the use of Doppler ultrasound in multicystic dysplastic kidneys. Pediatr Radiol 21:203–204
Hildebrandt F, Waldherr R, Kutt R et al (1992) The nephronophthisis complex: clinical and genetic aspects. Clin Invest 70:802–808
Hildebrandt F (1997) Nephronophthisis. In: Barrat MT, Avner ED, Harmon WE (eds) Pediatric nephrology. Lippincott Williams & Wilkins, Baltimore, pp 453–458
Hildebrandt F, Otto F (2005) Cilia and centrosomes: a unifying pathogentic concept for cystic kidney disease? Nat Rev Genet 6:928–940
Hildebrandt F, Benzing T, Katsanis N (2011) Ciliopathies. N Engl J Med 364:1533–1543
Hogg RJ (1992) Acquired cystic kidney disease in children prior to the start of dialysis. Pediatr Nephrol 6:176–178
Hoyer PF (1996a) Niere. In: Hoffman V, Deeg KH, Hoyer PF (eds) Ultraschalldiagnostik in der Pädiatrie und Kinderchirurgie. Thieme, Stuttgart/New York, pp 345–361
Hoyer PF (1996b) Nierentumoren. In: Hoffman V, Deeg KH, Hoyer PF (eds) Ultraschalldiagnostik in der Pädiatrie und Kinderchirurgie. Thieme, Stuttgart/New York, pp 406–412
Huland H (1986) Hydronephrotische Atrophie. In: Hohenfellner R, Thüroff JW, Schulte-Wissermann H (eds) Kinderurologie in Klinik und Praxis. Thieme, Stuttgart/New York, pp 18–29
Huttunen NP (1976) Congenital nephrotic syndrome of Finnish type. Study of 75 cases. Arch Dis Child 51:344–348
Iorember FM, Vehaskari MV (2014) Uromodelin: a old friend with new roles in health and disease. Pediatr Nephrol 29:1151–1158
Jeon A, Cramer BC, Walsh E et al (1999) A spectrum of segmental multicystic renal dysplasia. Pediatr Radiol 29:309–315
Joshi VV, Kasznica J (1984) Clinicopathologic spectrum of glomerulocystic kidneys: report of two cases and a brief review of literature. Pediatr Pathol 2:171–186
Jurkovic D, Geipel A, Gruboeck K et al (1995) Three-dimensional ultrasound for the assessment of uterine anatomy and detection of congenital anomalies: a comparison with hysterosalpingography and two-dimensional sonography. Ultrasound Obstet Gynecol 5:233–237
Kaplan BS, Rabin I, Nogrady MB et al (1977) Autosomal dominant polycystic renal disease in children. J Pediatr 90:782–783
Kaplan BS, Kaplan P, Dechadarievan JP et al (1988) Variable expression of autosomal recessive polycystic kidney disease and congenital hepatic fibrosis within one family. Am J Med Genet 29:639–647
Kaplan BS, Fay J, Shah V et al (1989a) Autosomal recessive polycystic kidney disease. Pediar Nephrol 3:43–49
Kaplan BS, Kaplan P, Rosenberg HK et al (1989b) Polycystic kidney diseases in childhood. J Pediatr 115:867–880
Kaplan BS, Gordon I, Pincott J et al (1989c) Familial hypoplastic glomerulocystic kidney disease: a definite entity with dominant inheritance. Am J Med Genet 34:569–573
Kasiske BL, Umen AJ (1986) The influence of age, sex, race and body habitus on kidney weight in humans. Arch Pathol Lab Med 110:55–60
Kääriäinen H, Koskinies O, Norio R (1988a) Dominant and recessive polycystic kidney disease in children: evaluation of clinical features and laboratory data. Pediatr Nephrol 2:296–302
Kääriäinen H, Jääskelainen J, Kivisaari L et al (1988b) Dominant and recessive polycystic kidney disease in children: classification by intravenous pyelography, ultrasound, and computed tomography. Pediatr Radiol 18:45–50
Kern S, Zimmerhackl LB, Hildebrandt F et al (1999) Rare MR urography: a new diagnostic method in autosomal recessive polycystic kidney disease. Acta Radiol 40:543–544
Kestilä M, Lenkkeri U, Lamerdin J et al (1998) Positionally cloned gene for a novel glomerular protein – nephrin – is mutated in congenital nephrotic syndrome. Mol Cell 1:575–582
Kiechl-Kohlendorfer U, Geley T, Maurer K, Gassner I (2011) Uterus didelphys with unilateral vaginal atresia: multicystic dysplastic kidney is the precursor of “renal agenesis” and the key to early diagnosis of this genital anomaly. Pediatr Radiol 41:1112–1116
Kim AY, Kim SH, Kim YJ et al (1999) Contrast-enhanced power Doppler sonography for the differentiation of cystic renal lesions: preliminary study. J Ultrasound Med 18:581–588
Kissane JM (1990) Renal cysts in pediatric patients: a classification and overview. Pediatr Nephrol 4:69–70
Kjessler B, Johansson SOG, Sherman MS et al (1975) Alphafetoprotein in antenatal diagnosis of congenital nephrosis. Lancet 1:123–124
Krestin GP (1990) Morphologic and functional MR of the kidneys and adrenal glands. Field & Wood, Philadelphia
Krull E, Hoyer PF, Habenicht R et al (1990) Multicystic kidney dysplasia. Mschr Kinderheilkd 138:202–205
Kullendorff CM (1990) Surgery in unilateral multicystic kidney. Z Kinderchir 45:235–237
Landry JL, Dodat H, Pelizzo G et al (1999) Dysplasie kystique du rete testis et agenesie renale ipsilaterale chez l’enfant. Arch Pediatr 6:416–420
Leichter HE, Dietrich R, Salusky IB et al (1988) Acquired cystic kidney disease in children undergoing long-term dialysis. Pediatr Nephrol 2:8–11
Levine E (1992) Renal cell carcinoma in uremic acquired renal cystic disease: incidence, detection and management. Urol Radiol 13:203–210
Lieberman E, Salinas-Madeigal L, Gwinn JL et al (1971) Infantile polycystic disease of the kidney and the liver: clinical, pathological and radiological correlation and comparison with congenital hepatic fibrosis. Medicine 50:277–318
Manish J, LeQuesne GW, Bourne AJ et al (1997) High resolution ultrasonography in the differential diagnosis of cystic diseases of the kidney in infancy and childhood: preliminary experiences. J Ultrasound Med 16:235–240
McDonald RA, Avner ED (1991) Inherited polycystic kidney disease in children. Semin Nephrol 11:632–642
McDonald RA, Watkins SL, Avner ED (1997) Polycystic kidney disease. In: Barrat MT, Avner ED, Harmon WE (eds) Pediatric nephrology. Lippincott Williams & Wilkins, Baltimore, pp 459–474
McHugh K, Stringer D, Hebert D (1991) Simple renal cyst in children: diagnosis and follow-up with US. Radiology 178:383–385
Morcos SK (2009) Non-neoplatsic cystic renal lesions. In: Morcos SK, Thomson H (eds) Urogenital imaging: a problem-oriented approach. Wiley-Blackwell, Oxford, pp 75–97
Nelson TR, Downey DB, Pretorius DH et al (1999) Three-dimensional ultrasound. Lippincrott Williams & Wilkins, Philadelphia, pp 111–127
Orejas G, Malaga S, Santos S et al (1992) Multicystic dysplastic kidney: absence of complications in patients treated conservatively. Child Nephrol Urol 12:35–39
Osathanondh V, Potter EL (1964) Pathogenesis of polycystic kidneys: survey of results of microdissection. Arch Pathol 77:510–519
Osathanondh V, Potter EL (1966) Development of human kidney as shown by microdissection. Arch Pathol 82:391–411
Palubinskas AJ (1963) Renal pyramidal structure opacification in excretory urography and its relation to medullary sponge kidney. Radiology 81:963–970
Patriquin HB, O’Regan S (1985) Medullary sponge kidney in childhood. AJR Am J Roentgenol 145:315–319
Patten RM, Mack LA, Wang KY et al (1990) The fetal genitourinary tract. Radiol Clin North Am 28:115–130
Porch P, Noe HN, Stapleton FB (1986) Unilateral presentation of adult-type polycystic kidney disease in children. J Urol 135:744–746
Proesmans W, Van Damme B, Casaer P et al (1982) Autosomal dominant polycystic kidney disease in the neonatal period: association with a cerebral arteriovenous malformation. Pediatrics 70:971–975
Reiner I, Donell S, Jones M et al (1992) Percutaneous sclerotherapy for simple renal cysts in children. Br J Radiol 65:281–282
Ring E, Petritsch P, Riccabona M et al (1990) Therapie und Prognose von Kindern mit pränatal diagnostizierten Harnwegsfehlbildungen. Wien Klin Wochenschr 102:463–466
Ring E, Petritsch P, Riccabona M et al (1993) Welche Therapie erfordert die pränatal diagnostizierte multizystische Nierendysplasie? Klin Padiatr 205:150–152
Riccabona M, Ring E, Petritsch G et al (1993a) Colour Doppler sonography in the differential diagnosis of congenital unilateral cystic renal malformations. Z Geburtsh Perinatol 197:283–287
Riccabona M, Ring E, Fueger G et al (1993b) Doppler sonography in congenital ureteropelvic junction obstruction and congenital muticystic kidney disease. Pediatr Radiol 23:502–505
Riccabona M, Ring E, Häusler M et al (1999a) Prenatally recognised multicystic segmental nephroma. Z Geburtsh Neonatol 203:255–257
Riccabona M, Szolar DH, Preidler KW et al (1999b) Renal masses–evaluation by amplitude coded colour Doppler sonography and multiphasic enhanced contrast CT. Acta Radiol 40:457–461
Riccabona M, Simbrunner J, Ring E, Ebner F, Fotter R (2002) Feasibility of MR-urography in neo-nates and infants with anomalies of the upper urinary tract. Eur Radiol 12:1442–1450
Riccabona M, Ruppert-Kohlmeier A, Ring E, Maier C, Lusuardi L, Riccabona M (2004a) Potential impact of pediatric MR-urography on the imaging algorithm in patients with a functional single kidney? AJR Am J Roentgenol 183:795–800
Riccabona M, Michael R, Koen M et al (2004b) Magnetic resonance urography – a new gold standard for evaluation of solitary kidneys and renal buds. J Urol 171:1642–1646
Riccabona M, Avni F, Dacher JN et al (2011) ESPR uroradiology task force and ESUR paediatric working group: imaging recommendations in paediatric uroradiology, part IV Minutes of the ESPR uroradiology task force mini-symposium on imaging in childhood renal hypertension and imaging of renal trauma in children. Pediatr Radiol 41(7):939–944
Riccabona M, Avni FE (2011) MR imaging of the paediatric abdomen. In: Gourtsonyiannis N (ed) Clinical MRI of the abdomen. Why, how, when. Springer, Heidelberg/Dordrecht/London/New York, pp 639–676, ISBN 978-3-540-85689-4
Riccabona M, Avni F, Damasio B et al (2012) ESPR Uroradiology Task Force and ESUR Paediatric Working Group – Imaging recommendations in Paediatric Uroradiology, Part V: childhood cystic kidney disease, childhood renal transplantation, and contrast-enhanced ultrasound in children. Pediatr Radiol 42:1275–1283
Riccabona M (2014) Paediatric 3D-Ultrasound (3DUS). J Ultrasound 14:5–20
Riccabona M, Lobo ML, Willi U et al (2014) ESPR Uroradiology Task Force and ESUR Paediatric Working Group – imaging recommendations in Paediatric Uroradiology, Part VI: childhood renal biopsy and imaging of neonatal and infant genital tract. Minutes from the Task Force session at the annual ESPR Meeting 2012 in Athens on childhood renal biopsy and imaging neonatal genitalia. Pediatr Radiol 44:496–502
Roy S, Dillon MJ, Trompeter RS et al (1997) Autosomal recessive kidney disease: long term outcome of neonatal survivors. Pediatr Nephrol 11:302–306
Schneider K, Fendel H (1995) Urogenitaltrakt. In: Ebel KD, Willich E, Richter E (eds) Differentialdiagnostik in der pädiatrischen Radiologie, Band II. Thieme, Stuttgart/New York, pp 343–392
Sedman A, Bell P, Manco-Johnson M et al (1987) Autosomal dominant polycystic kidney disease in childhood: a longitudinal study. Kidney Int 31:1000–1005
Sellers B, Richie JP (1978) Glomerulocystic kidney: proposed etiology and pathogenesis. J Urol 119:678–680
Shaikewitz ST, Chapman A (1993) Autosomal recessive polycystic kidney disease: issues regarding the variability of clinical presentation. J Am Soc Nephrol 3:1858–1862
Shapiro SS, Wagreich J, Parsons RB et al (1998) Tissue harmonic imaging sonography: evaluation of image quality compared with conventional sonography. AJR Am J Roentgenol 171:701–707
Siegel MJ, McAlister WH (1980) Simple cysts of the kidney in children. J Urol 123:75–78
Sigmund G, Stöver B, Zimmerhackl LB et al (1991) RARE MR urography in the diagnosis of upper urinary tract abnormalities in children. Pediatr Radiol 21:416–420
Strand WR, Rushton HG, Markle BM et al (1989) Autosomal dominant polycystic kidney disease in infants: asymmetric disease mimicking a unilateral renal mass. J Urol 141:1151–1153
Stockamp K (1986) Zystische Nierenerkrankungen. In: Hohenfellner R, Thüroff JW, Schulte-Wissermann H (eds) Kinderurologie in Klinik und Praxis. Thieme, Stuttgart/New York, pp 262–266
Srivastava T, Garola RE, Hellerstein S (1999) Autosomal dominant inheritance of multicystic dysplastic kidney. Pediatr Nephrol 13:481–483
Szolar DH, Kammerhuber F, Altziebler S et al (1997) Multiphasic helical CT of the kidney: Increased conspicuity for detection and characterisation of small (<3 cm) renal masses. Radiology 202:211–217
Takeuchi T, Tanaka T, Tokuyama H et al (1984) Multilocular cystic adenocarcinoma: a case report and review of the literature. J Surg Oncol 25:136–140
Tada S, Yamagishi J, Kobayashi H et al (1983) The incidence of simple renal cysts by computed tomography. Clin Radiol 34:437–439
Tanago EA (1975) Embryology of the genitourinary system. In: Smith R (ed) General urology. Lange, Los Altos
Terrier F, Hricak H, Justich E et al (1986) The diagnostic value of renal cortex-to-medulla contrast on magnetic resonance imaging. Eur J Radiol 6:121–126
Theissig F, Hempel J, Schubert J (1986) Multilocular cystic nephroma simulating kidney carcinoma. Ztschr Urol Nephrol 79:263–267
Thomas JD, Rubin DN (1998) Tissue harmonic imaging: why does it work? J Am Soc Echocardiogr 11:803–808
Upadhyay AK, Neely JA (1989) Cystic nephroma: an emerging entity. Anal Royal Col Surg England 71:381–383
Urban BA (1997) The small renal mass: what is the role of multiphasic helical sacnning. Radiology 202:22–23
Vester U, Kranz B, Hoyer PF (2010) The diagnostic value of ultrasound in cystic kidney disease. Pediatr Nephrol 25:231–240
Watkins SL, McDonald RA, Avner ED (1997) Renal dysplasia, hypoplasia and miscellaneous cystic disorders. In: Barrat MT, Avner ED, Harmon WE (eds) Pediatric nephrology. Lippincott Williams & Wilkins, Baltimore, pp 415–426
Wittingham TA (1999) Tissue harmonic imaging. Eur Radiol 9:323–326
Wood BP (1992) Renal cystic disease in infants and children. Urol Radiol 14:284–295
Woolf AS (1997) The kidney: embryology. In: Barrat MT, Avner ED, Harmon WE (eds) Pediatric nephrology. Lippincott Williams & Wilkins, Baltimore, pp 1–17
Woolf R, Allen W (1953) Concomitant malformations: the frequent simultaneous occurrence of congenital malformations of the reproductive and the urinary tract. Obstet Gynecol 2:236–265
Worthington JL, Shackelford GD, Cole BR et al (1988) Sonographically detectable cysts in polycystic kidney disease in newborn and young infants. Pediatr Radiol 18:287–293
Yendt ER (1990) Medullary sponge kidney. In: Gadner KD, Bernstein J (eds) The cystic kidney. Kluwer, Dordrecht, pp 379–392
Zejil C, Roefs B, Boer K et al (1999) Clinical outcome and follow-up of sonographically suspected in utero urinary tract anomalies. J Clin Ultrasound 27:21–28
Zerres K (1987) Genetics of cystic kidney diseases: criteria for classification and genetic counseling. Pediatr Nephrol 1:397–404
Zerres K, Hansmann M, Mallman R et al (1988) Autosomal recessive polycystic kidney disease: problems of prenatal diagnosis. Prenat Diagn 8:215–229
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Riccabona, M., Ring, E., Avni, F. (2018). Imaging in Renal Agenesis, Dysplasia, Hypoplasia, and Cystic Diseases of the Kidney. In: Riccabona, M. (eds) Pediatric Urogenital Radiology. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/978-3-319-39202-8_31
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