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Coagulopathies and Anticoagulation

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Principles of Adult Surgical Critical Care

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Abstract

Acute hemorrhage, acute thrombosis, and management of anticoagulation are common challenges in critical care medicine. An array of acquired conditions result in coagulopathy. These include liver disease, acute trauma, cardiopulmonary bypass, and anticoagulation with both standard and novel agents. Furthermore, congenital or acquired conditions such as von Willebrand disease and hemophilia can complicate otherwise straightforward surgery or can result in life-threatening bleeding from relatively minor trauma. Patients also frequently require the initiation or discontinuation of anticoagulation while in the ICU. The following chapter describes the most common coagulopathies seen in the ICU and outlines a practical management approach to reversing coagulopathy and managing anticoagulation in the critical care setting.

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Change history

  • 04 May 2018

    An erratum has been published.

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  1. Division of Traumatology, Surgical Critical Care & Emergency Surgery, Penn Presbyterian Medical Center, Philadelphia, PA, 19104, USA

    Jeremy W. Cannon MD, SM

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Correspondence to Jeremy W. Cannon MD, SM .

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  1. Trauma, Surgical Critical Care, Emergency Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

    Niels D. Martin

  2. Trauma, Surgical Critical Care, Emergency Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

    Lewis J. Kaplan

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Cannon, J.W. (2016). Coagulopathies and Anticoagulation. In: Martin, N.D., Kaplan, L.J. (eds) Principles of Adult Surgical Critical Care. Springer, Cham. https://doi.org/10.1007/978-3-319-33341-0_26

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