Abstract
Radical cystectomy is suited to a minimally invasive approach, and robotic surgery holds the potential for improving perioperative morbidity compared with open surgery, without a compromise of oncological efficacy. Recent meta-analyses have shown that minimally invasive cystectomy is associated with lower morbidity, shorter length of stay, reduced blood loss and transfusion rates, less post-operative ileus and a reduced need for analgesics. The short and medium term oncological efficacy of robotic cystectomy has been shown to be equivalent to open surgery. However, larger studies with longer follow-up are needed in order to obtain higher levels of evidence.
Keywords
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Huang GJ, Stein JP. Open radical cystectomy with lymphadenectomy remains the treatment of choice for invasive bladder cancer. Curr Opin Urol. 2007;17(5):369–75.
Novotny V, Hakenberg OW, Wiessner D, Heberling U, Litz RJ, Oehlschlaeger S, et al. Perioperative complications of radical cystectomy in a contemporary series. Eur Urol. 2007;51(2):397–401. discussion 401–2
Novara G, Catto JWF, Wilson T, Annerstedt M, Chan K, Murphy DG, et al. Systematic review and cumulative analysis of perioperative outcomes and complications after robot-assisted radical cystectomy. Eur Urol. 2015;67(3):376–401.
Luchey AM, Agarwal G, Poch MA. Robotic-assisted radical cystectomy. Cancer control. J Moffitt Cancer Cent. 2015;22(3):301–6.
Xia L, Wang X, Xu T, Zhang X, Zhu Z, Qin L, et al. Robotic versus open radical cystectomy: an updated systematic review and meta-analysis. PLoS One. 2015;10(3):e0121032.
Yuh B, Wilson T, Bochner B, Chan K, Palou J, Stenzl A, et al. Systematic review and cumulative analysis of oncologic and functional outcomes after robot-assisted radical cystectomy. Eur Urol. 2015;67(3):402–22.
Raza SJ, Wilson T, Peabody JO, Wiklund P, Scherr DS, Al-Daghmin A, et al. Long-term oncologic outcomes following robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol. 2015;68(4):721–8.
Snow-Lisy DC, Campbell SC, Gill IS, Hernandez AV, Fergany A, Kaouk J, et al. Robotic and laparoscopic radical cystectomy for bladder cancer: long-term oncologic outcomes. Eur Urol. 2014;65(1):193–200.
Parekh DJ, Messer J, Fitzgerald J, Ercole B, Svatek R. Perioperative outcomes and oncologic efficacy from a pilot prospective randomized clinical trial of open versus robotic assisted radical cystectomy. J Urol. 2013;189(2):474–9.
Bochner BH, Dalbagni G, Sjoberg DD, Silberstein J, Keren Paz GE, Donat SM, et al. Comparing open radical cystectomy and robot-assisted laparoscopic radical cystectomy: a randomized clinical trial. Eur Urol. 2015;67(6):1042–50.
Nix J, Smith A, Kurpad R, Nielsen ME, Wallen EM, Pruthi RS. Prospective randomized controlled trial of robotic versus open radical cystectomy for bladder cancer: perioperative and pathologic results. Eur Urol. 2010;57(2):196–201.
Sánchez de Badajoz E, Gallego Perales JL, Reche Rosado A, de la Cruz JM G, Jiménez Garrido A. Radical cystectomy and laparoscopic ileal conduit. Arch Esp Urol. 1993;46(7):621–4.
Gill IS, Fergany A, Klein EA, Kaouk JH, Sung GT, Meraney AM, et al. Laparoscopic radical cystoprostatectomy with ileal conduit performed completely intracorporeally: the initial 2 cases. Urology. 2000;56(1):26–9; discussion 29–30.
Gill IS, Kaouk JH, Meraney AM, Desai MM, Ulchaker JC, Klein EA, et al. Laparoscopic radical cystectomy and continent orthotopic ileal neobladder performed completely intracorporeally: the initial experience. J Urol. 2002;168(1):13–8.
Menon M, Hemal AK, Tewari A, Shrivastava A, Shoma AM, El-Tabey NA, et al. Nerve-sparing robot-assisted radical cystoprostatectomy and urinary diversion. BJU Int. 2003;92(3):232–6.
Yohannes P, Puri V, Yi B, Khan AK, Sudan R. Laparoscopy-assisted robotic radical cystoprostatectomy with ileal conduit urinary diversion for muscle-invasive bladder cancer: initial two cases. J Endourol Endourol Soc. 2003;17(9):729–32.
Beecken W-D, Wolfram M, Engl T, Bentas W, Probst M, Blaheta R, et al. Robotic-assisted laparoscopic radical cystectomy and intra-abdominal formation of an orthotopic ileal neobladder. Eur Urol. 2003;44(3):337–9.
Satyanarayana R, Kallingal G, Parekh D. Current status of robotic and laparoscopic techniques in radical cystectomy and diversion procedures for bladder cancer: review. Minerva Urol E Nefrol Ital J Urol Nephrol. 2014;66(1):1–14.
Yu H, Hevelone ND, Lipsitz SR, Kowalczyk KJ, Nguyen PL, Choueiri TK, et al. Comparative analysis of outcomes and costs following open radical cystectomy versus robot-assisted laparoscopic radical cystectomy: results from the US Nationwide Inpatient Sample. Eur Urol. 2012;61(6):1239–44.
Ishii H, Rai BP, Stolzenburg J-U, Bose P, Chlosta PL, Somani BK, et al. Robotic or open radical cystectomy, which is safer? A systematic review and meta-analysis of comparative studies. J Endourol Endourol Soc. 2014;28(10):1215–23.
Hayn MH, Hussain A, Mansour AM, Andrews PE, Carpentier P, Castle E, et al. The learning curve of robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol. 2010;58(2):197–202.
Pruthi RS, Smith A, Wallen EM. Evaluating the learning curve for robot-assisted laparoscopic radical cystectomy. J Endourol Endourol Soc. 2008;22(11):2469–74.
Guru KA, Wilding GE, Piacente P, Thompson J, Deng W, Kim HL, et al. Robot-assisted radical cystectomy versus open radical cystectomy: assessment of postoperative pain. Can J Urol. 2007;14(6):3753–6.
Leow JJ, Reese SW, Jiang W, Lipsitz SR, Bellmunt J, Trinh Q-D, et al. Propensity-matched comparison of morbidity and costs of open and robot-assisted radical cystectomies: a contemporary population-based analysis in the United States. Eur Urol. 2014;66(3):569–76.
Ishii Y, Itoh N, Takahashi A, Masumori N, Ikeda T, Tsukamoto T. Bladder cancer discovered by ovarian metastasis: cytokeratin expression is useful when making differential diagnosis. Int J Urol Off J Jpn Urol Assoc. 2005;12(1):104–7.
Tang K, Xia D, Li H, Guan W, Guo X, Hu Z, et al. Robotic vs. open radical cystectomy in bladder cancer: a systematic review and meta-analysis. Eur J Surg Oncol J Eur Soc Surg Oncol Br Assoc Surg Oncol. 2014;40(11):1399–411.
Hellenthal NJ, Hussain A, Andrews PE, Carpentier P, Castle E, Dasgupta P, et al. Lymphadenectomy at the time of robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. BJU Int. 2011;107(4):642–6.
Khan MS, Elhage O, Challacombe B, Murphy D, Coker B, Rimington P, et al. Long-term outcomes of robot-assisted radical cystectomy for bladder cancer. Eur Urol. 2013;64(2):219–24.
Josephson DY, Chen JA, Chan KG, Lau CS, Nelson RA, Wilson TG. Robotic-assisted laparoscopic radical cystoprostatectomy and extracorporeal continent urinary diversion: highlight of surgical techniques and outcomes. Int J Med Robot. 2010;6(3):315–23.
Kauffman EC, Ng CK, Lee MM, Otto BJ, Wang GJ, Scherr DS. Early oncological outcomes for bladder urothelial carcinoma patients treated with robotic-assisted radical cystectomy. BJU Int. 2011;107(4):628–35.
Martin AD, Nunez RN, Pacelli A, Woods ME, Davis R, Thomas R, et al. Robot-assisted radical cystectomy: Intermediate survival results at a mean follow-up of 25 months. BJU Int. 2010;105(12):1706–9.
Mmeje CO, Nunez-Nateras R, Nielsen ME, Pruthi RS, Smith A, Wallen EM, et al. Oncologic outcomes for lymph node-positive urothelial carcinoma patients treated with robot assisted radical cystectomy: with mean follow-up of 3.5 years. Urol Oncol Semin Orig Investig. 2013;31(8):1621–7.
Nazmy M, Yuh B, Kawachi M, Lau CS, Linehan J, Ruel NH, et al. Early and late complications of robot-assisted radical cystectomy: a standardized analysis by urinary diversion type. J Urol. 2014;191(3):681–7.
Xylinas E, Green DA, Otto B, Jamzadeh A, Kluth L, Lee RK, et al. Robotic-assisted radical cystectomy with extracorporeal urinary diversion for urothelial carcinoma of the bladder: analysis of complications and oncologic outcomes in 175 patients with a median follow-up of 3 years. Urology. 2013;82(6):1323–9.
Yuh B, Torrey RR, Ruel NH, Wittig K, Tobis S, Linehan J, et al. Intermediate-term oncologic outcomes of robot-assisted radical cystectomy for urothelial carcinoma. J Endourol. 2014;28(8):939–45.
Raza SJ, Al-Daghmin A, Zhuo S, Mehboob Z, Wang K, Wilding G, et al. Oncologic outcomes following robot-assisted radical cystectomy with minimum 5-year follow-up: the Roswell Park cancer Institute experience. Eur Urol. 2014;66(5):920–8.
Khan MS, Challacombe B, Elhage O, Rimington P, Coker B, Murphy D, et al. A dual-centre, cohort comparison of open, laparoscopic and robotic-assisted radical cystectomy. Int J Clin Pract. 2012;66(7):656–62.
Nepple KG, Strope SA, Grubb RL III, Kibel AS. Early oncologic outcomes of robotic vs. open radical cystectomy for urothelial cancer. Urol Oncol Semin Orig Investig. 2013;31(6):894–8.
Gandaglia G, De Groote R, Geurts N, D’Hondt F, Montorsi F, Novara G, et al. Oncologic outcomes of robot-assisted radical cystectomy: results of a high-volume robotic center. J Endourol Endourol Soc. 2016;30(1):75–82.
Nguyen DP, Al Hussein Al Awamlh B, Wu X, O’Malley P, Inoyatov IM, Ayangbesan A, et al. Recurrence patterns after open and robot-assisted radical cystectomy for bladder cancer. Eur Urol. 2015;68(3):399–405.
Ost MC, Patel KP, Rastinehad AR, Chu PY, Anderson AE, Smith AD, et al. Pneumoperitoneum with carbon dioxide inhibits macrophage tumor necrosis factor-α secretion: source of transitional-cell carcinoma port-site metastasis, with prophylactic irrigation strategies to decrease laparoscopic oncologic risks. J Endourol. 2008;22(1):105–12.
Torrey RR, Chan KG, Yip W, Josephson DY, Lau CS, Ruel NH, et al. Functional outcomes and complications in patients with bladder cancer undergoing robotic-assisted radical cystectomy with extracorporeal indiana pouch continent cutaneous urinary diversion. Urology. 2012;79(5):1073–8.
Tyritzis SI, Hosseini A, Collins J, Nyberg T, Jonsson MN, Laurin O, et al. Oncologic, functional, and complications outcomes of robot-assisted radical cystectomy with totally intracorporeal neobladder diversion. Eur Urol. 2013;64(5):734–41.
Canda AE, Atmaca AF, Altinova S, Akbulut Z, Balbay MD. Robot-assisted nerve-sparing radical cystectomy with bilateral extended pelvic lymph node dissection (PLND) and intracorporeal urinary diversion for bladder cancer: initial experience in 27 cases. BJU Int. 2012;110(3):434–44.
Messer JC, Punnen S, Fitzgerald J, Svatek R, Parekh DJ. Health-related quality of life from a prospective randomised clinical trial of robot-assisted laparoscopic vs open radical cystectomy. BJU Int. 2014;114(6):896–902.
Aboumohamed AA, Raza SJ, Al-Daghmin A, Tallman C, Creighton T, Crossley H, et al. Health-related quality of life outcomes after robot-assisted and open radical cystectomy using a validated bladder-specific instrument: a multi-institutional study. Urology. 2014;83(6):1300–8.
Smith A, Kurpad R, Lal A, Nielsen M, Wallen EM, Pruthi RS. Cost analysis of robotic versus open radical cystectomy for bladder cancer. J Urol. 2010;183(2):505–9.
Martin AD, Nunez RN, Castle EP. Robot-assisted radical cystectomy versus open radical cystectomy: a complete cost analysis. Urology. 2011;77(3):621–5.
Smith AB, Raynor M, Amling CL, Busby JE, Castle E, Davis R, et al. Multi-institutional analysis of robotic radical cystectomy for bladder cancer: perioperative outcomes and complications in 227 patients. J Laparoendosc Adv Surg Tech A. 2012;22(1):17–21.
Kurpad R, Woods M, Pruthi R. Current status of robot-assisted radical cystectomy and intracorporeal urinary diversion. Curr Urol Rep. 2016;17(6):42.
Chan KG, Collins JW, Wiklund NP. Robot-assisted radical cystectomy: extracorporeal vs intracorporeal urinary diversion. J Urol. 2015;193(5):1467–9.
Ahmed K, Khan SA, Hayn MH, Agarwal PK, Badani KK, Balbay MD, et al. Analysis of intracorporeal compared with extracorporeal urinary diversion after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol. 2014;65(2):340–7.
Pyun JH, Kim HK, Cho S, Kang SG, Cheon J, Lee JG, et al. Robot-assisted radical cystectomy with total intracorporeal urinary diversion: comparative analysis with extracorporeal urinary diversion. J Laparoendosc Adv Surg Tech. 2016;26(5):349–55.
Chan KG, Guru K, Wiklund P, Catto J, Yuh B, Novara G, et al. Robot-assisted radical cystectomy and urinary diversion: technical recommendations from the Pasadena Consensus Panel. Eur Urol. 2015;67(3):423–31.
Smith ND, Castle EP, Gonzalgo ML, Svatek RS, Weizer AZ, Montgomery JS, et al. The RAZOR (randomized open vs robotic cystectomy) trial: study design and trial update. BJU Int. 2015;115(2):198–205.
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Venkatramani, V., Parekh, D.J. (2018). Robot-Assisted Radical Cystectomy Versus Open Radical Cystectomy. In: Hemal, A., Menon, M. (eds) Robotics in Genitourinary Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-20645-5_59
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DOI: https://doi.org/10.1007/978-3-319-20645-5_59
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