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Bone Quality Assessment at the Atomic Scale

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The Computational Mechanics of Bone Tissue

Part of the book series: Lecture Notes in Computational Vision and Biomechanics ((LNCVB,volume 35))

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Abstract

The assessment of osteoporosis regarding bone mass and microarchitecture “quality” contributes in determining fracture risk. Therefore, the crystalline structure of hydroxyapatite may indicate the quality of trabecular bones through the identification of crystallite sizes, microhardness and microdeformation values and calcium and phosphorous proportions in the three types of bones: normal, osteopenic, and osteoporotic. Nine L1 vertebrae-dried trabecular bones from human cadavers were used. The characterization of the three types of bones was made through scanning electron microscopy, EDS, microhardness, and X-ray diffractometry with the Rietveld refinement method. The results show that the microstructural characterization possibilities the identification of the three types of bones: normal, osteopenic, and osteoporotic, allowing the detection of osteoporosis based on bone quality.

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Authors and Affiliations

  1. Departamento de Engenharia de Materiais, Universidade de São Paulo (USP), Escola de Engenharia de São Carlos, Av. Trabalhador Saocarlense, 400—Parque Arnold Schimidt, 13565-590, São Carlos, SP, Brazil

    J. M. D. A. Rollo & R. S. Boffa

  2. Departamento de Engenharia Mecânica, Universidade de São Paulo (USP), Escola de Engenharia de São Carlos, Av. Trabalhador Saocarlense, 400 – Parque Arnold Schimidt, 13565-590, São Carlos, SP, Brazil

    R. Cesar & R. Erbereli

  3. DCS - English Consultancy Services, Rua São Sebastião, 1795 – Sala 7, 13560-230, São Carlos, Brazil

    D. C. Schwab

  4. Instituto de Ortopedia E Traumatologia, HCFMUSP-OIT—Hospital de Clinicas da Faculdade de Medicina, Universidade de São Paulo (USP), Rua Dr. Ovidio Pires de Campos, 333 – Cerqueira Cesar, 05403-010, São Paulo, Brazil

    T. P. Leivas

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  1. J. M. D. A. Rollo
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Correspondence to J. M. D. A. Rollo .

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Editors and Affiliations

  1. Department of Mechanical Engineering, School of Engineering, Polytechnic of Porto (ISEP), Porto, Portugal

    Jorge Belinha

  2. Departament de Patologia i Terapèutica Experimental, University of Barcelona, Barcelona, Spain

    Maria-Cristina Manzanares-Céspedes

  3. Department of Mechanical Engineering, University of Aveiro, Aveiro, Portugal

    António M. G. Completo

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Rollo, J.M.D.A., Boffa, R.S., Cesar, R., Erbereli, R., Schwab, D.C., Leivas, T.P. (2020). Bone Quality Assessment at the Atomic Scale. In: Belinha, J., Manzanares-Céspedes, MC., Completo, A. (eds) The Computational Mechanics of Bone Tissue. Lecture Notes in Computational Vision and Biomechanics, vol 35. Springer, Cham. https://doi.org/10.1007/978-3-030-37541-6_2

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