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Deep Learning in Textural Medical Image Analysis

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Deep Learning in Healthcare

Part of the book series: Intelligent Systems Reference Library ((ISRL,volume 171))

Abstract

One of the characteristics of medical image analysis is that several medical images are not in the structure domain like natural images but in the texture domain. This chapter introduces a new transfer learning method, called “two-stage feature transfer,” to analyze textural medical images by deep convolutional neural networks. In the process of the two-stage feature transfer learning, the models are successively pre-trained with both natural image dataset and textural image dataset to get a better feature representation which cannot be derived from either of these datasets. Experimental results show that the two-stage feature transfer improves the generalization performance of the convolutional neural network on a textural lung CT pattern classification. To explain the mechanism of a transfer learning on convolutional neural networks, this chapter also shows analysis results of the obtained feature representations by an activation visualization method, and by measuring the frequency response of trained neural networks, in both qualitative and quantitative ways, respectively. These results demonstrate that such successive transfer learning enables networks to grasp both structural and textural visual features and be helpful to extracting good features from the textural medical images.

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Notes

  1. 1.

    Interchanging the order of source domains for pretraining, i.e., using textural images before natural images, make the generalization performance worse because of the catastrophic forgetting of knowledge [8]. First pretraining should be done with a natural image dataset also by considering the computational cost of the training with natural images and the availability of the pretrained model.

  2. 2.

    Most studies on DLDs classify them into six classes with no discrimination between RET and GGO. This work explicitly discriminates them in a more precise and up-to-date manner.

  3. 3.

    In fact, DCNNs works as a basis decomposition, which corresponds to a convolution “kernel” literally, instead of Fourier systems identified in frequency space. However, because the images have another isomorphic representation in Fourier space, this analysis can be meaningful.

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Correspondence to Aiga Suzuki .

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Suzuki, A., Sakanashi, H., Kido, S., Shouno, H. (2020). Deep Learning in Textural Medical Image Analysis. In: Chen, YW., Jain, L. (eds) Deep Learning in Healthcare. Intelligent Systems Reference Library, vol 171. Springer, Cham. https://doi.org/10.1007/978-3-030-32606-7_7

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