Abstract
Transfusion has played a critical role in the history and development of trauma care since the first blood bank was established 100 years ago. Rapid access to a full range of blood products saves lives. Initial treatment of massive hemorrhage is formulaic, attempting to replace lost blood volume, oxygen carrying capacity, and hemostatic activity simultaneously. This can be accomplished with whole blood, but components are currently more widely available and appear to be satisfactory when used in balanced ratios. Laboratory-guided resuscitation should be initiated when bleeding slows and is possible with viscoelastic testing or conventional laboratory tests.
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Murphy, C.H., Holcomb, J.B., Hess, J.R. (2020). The Evolution of Transfusion Therapy in Trauma. In: Siegler, M., Rogers Jr., S. (eds) Violence, Trauma, and Trauma Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-31246-6_16
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