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Normal Anatomy and Histology of the Kidney: Importance for Kidney Tumors

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Kidney Cancer

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Abstract

The knowledge of the normal anatomy and histology of the kidney is essential for the pathologist evaluating kidney tumors. Perturbations of normal kidney embryologic development can give rise to pediatric tumors, such as Wilms tumor, in addition to other renal anomalies. An understanding of gross and microscopic anatomy of normal kidney is requisite for accurate diagnosis and prognostic evaluation of malignant kidney tumors. Renal tumors can arise from the proximal tubules (e.g., clear cell and papillary carcinomas), distal nephron and collecting ducts (e.g., chromophobe, renal oncocytoma, and collecting duct carcinoma), or other normal microscopic components of the kidney (e.g., renal interstitial cell tumor, juxtaglomerular cell tumor). Guidelines for the gross examination of kidney tumor specimens have been laid out by the International Society of Urological Pathology (ISUP) and the College of American Pathologists (CAP) and are summarized in this chapter.

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Authors and Affiliations

  1. Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Weill Medical College of Cornell University, Houston, TX, USA

    Ziad M. El-Zaatari, Komal Arora, Mukul K. Divatia & Jae Y. Ro

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  1. Ziad M. El-Zaatari
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  2. Komal Arora
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  3. Mukul K. Divatia
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  4. Jae Y. Ro
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Corresponding author

Correspondence to Jae Y. Ro .

Editor information

Editors and Affiliations

  1. Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Weill Medical College of Cornell University, Houston, TX, USA

    Mukul K. Divatia

  2. Gulhane Military Medical Academy, School of Medicine, Department of Pathology, Ankara, Turkey

    Ayhan Ozcan

  3. Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Charles C. Guo

  4. Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Weill Medical College of Cornell University, Houston, TX, USA

    Jae Y. Ro

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El-Zaatari, Z.M., Arora, K., Divatia, M.K., Ro, J.Y. (2020). Normal Anatomy and Histology of the Kidney: Importance for Kidney Tumors. In: Divatia, M., Ozcan, A., Guo, C., Ro, J. (eds) Kidney Cancer. Springer, Cham. https://doi.org/10.1007/978-3-030-28333-9_3

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  • DOI: https://doi.org/10.1007/978-3-030-28333-9_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-28332-2

  • Online ISBN: 978-3-030-28333-9

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