Abstract
High-grade surface osteosarcoma is a high-grade bone-forming neoplasm which arises on the surface of the bone. It has a male predominance. Peak incidence is in the second decade of life. A majority of patients are in the second and third decades of life. Radiologically, the lesion presents a large mass with a broad-based attachment to the underlying bone. There is a dense to moderate mineralization with a fluffy immature appearance. There is partial cortical destruction and periosteal new bone. Histologically, it is identical to conventional osteosarcoma (osteoblastic, chondroblastic, fibroblastic subtypes). All tumors are high grade. Treatment consists of neoadjuvant chemotherapy followed by surgical resection with a wide margin.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Suggested Reading
Okada K, Unni KK, Swee RG, Sim FH. High-grade surface osteosarcoma: a clinicopathologic study of 46 cases. Cancer. 1999;85(5):1044–54.
Staals EL, Bacchini P, Bertoni F. High-grade surface osteosarcoma: a review of 25 cases from the Rizzoli Institute. Cancer. 2008;112(7):1592–9.
Vanel D, Picci P, De Paolis M, Mercuri M. Radiological study of 12 high-grade surface osteosarcomas. Skelet Radiol. 2001;30(12):667–71. Epub 2001 Aug 30
Wold LE, Unni KK, Beabout JW, Pritchard DJ. High-grade surface osteosarcomas. Am J Surg Pathol. 1984;8(3):181–6.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Inwards, C.Y., Wenger, D.E. (2020). High-Grade Surface Osteosarcoma. In: Santini-Araujo, E., Kalil, R.K., Bertoni, F., Park, YK. (eds) Tumors and Tumor-Like Lesions of Bone. Springer, Cham. https://doi.org/10.1007/978-3-030-28315-5_17
Download citation
DOI: https://doi.org/10.1007/978-3-030-28315-5_17
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-28314-8
Online ISBN: 978-3-030-28315-5
eBook Packages: MedicineMedicine (R0)