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Laparoscopic Heller Myotomy and Posterior Partial Fundoplication

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Foregut Surgery

Abstract

Achalasia is a rare primary esophageal motility disorder that causes mostly progressive dysphagia and regurgitation. The goal of therapy for achalasia is to provide symptom relief by reducing esophageal outflow resistance by disrupting the muscles at the esophagogastric junction (EGJ) to allow emptying by gravity. Although there are several options to achieve this goal, surgical myotomy with partial fundoplication has been shown to be very effective and able to strike a balance between relief of symptoms and control of abnormal GER. Since reflux of gastric contents into the aperistaltic esophagus may cause esophagitis, peptic strictures, Barrett’s esophagus, and even esophageal cancer, the addition of a partial fundoplication is very important. In this chapter, we will discuss the pros and cons of the different types of fundoplication.

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References

  1. Boeckxstaens GE, Zaninotto G, Richter JE. Achalasia. Lancet. 2014;383(9911):83–93. https://doi.org/10.1016/S0140-6736(13)60651-0.

    Article  PubMed  Google Scholar 

  2. Samo S, Carlson DA, Gregory DL, Gawel SH, Pandolfino JE, Kahrilas PJ. Incidence and prevalence of achalasia in Central Chicago, 2004–2014, since the widespread use of high-resolution manometry. Clin Gastroenterol Hepatol. 2014;15(1):34–48. https://doi.org/10.1016/j.cgh.2016.08.030.

    Article  Google Scholar 

  3. Zaninotto G, Bennett C, Boeckxstaens G, et al. The 2018 ISDE achalasia guidelines. Dis Esophagus. 2018;31(9):1–29. https://doi.org/10.1093/dote/doy071.

    Article  Google Scholar 

  4. Enestvedt BK, Lucas Williams J, Sonnenberg A. Epidemiology and practice patterns of achalasia in a large multi-center database. Aliment Pharmacol Ther. 2013;33(11):1–9. https://doi.org/10.1111/j.1365-2036.2011.04655.x.Epidemiology.

    Article  Google Scholar 

  5. Molena D, Yang SC. Surgical management of end-stage achalasia. Semin Thorac Cardiovasc Surg. 2012;24(1):19–26. https://doi.org/10.1053/j.semtcvs.2012.01.015.

    Article  PubMed  Google Scholar 

  6. Schlottmann F, Patti MG. Esophageal achalasia: current diagnosis and treatment. Expert Rev Gastroenterol Hepatol. 2018;12(7):711–21. https://doi.org/10.1080/17474124.2018.1481748.

    Article  CAS  PubMed  Google Scholar 

  7. Pressman A, Behar J. Etiology and pathogenesis of idiopathic achalasia. J Clin Gastroenterol. 2017;51(3):195–202. https://doi.org/10.1097/MCG.0000000000000780.

    Article  PubMed  Google Scholar 

  8. Gockel I, Bohl JRE, Doostkam S, Eckardt VF, Junginger T. Spectrum of histopathologic findings in patients with achalasia reflects different etiologies. J Gastroenterol Hepatol. 2006;21(4):727–33. https://doi.org/10.1111/j.1440-1746.2006.04250.x.

    Article  PubMed  Google Scholar 

  9. Goyal RK, Chaudhury A. Pathogenesis of achalasia: lessons from mutant mice. Gastroenterology. 2010;139(4):1086–90. https://doi.org/10.1053/j.gastro.2010.08.013.

    Article  PubMed  Google Scholar 

  10. Schlottmann F, Herbella F, Allaix ME, Patti MG. Modern management of esophageal achalasia: from pathophysiology to treatment. Curr Probl Surg. 2018;55(1):10–37. https://doi.org/10.1067/j.cpsurg.2018.01.001.

    Article  PubMed  Google Scholar 

  11. Leeuwenburgh I, Scholten P, Alderliesten J, et al. Long-term esophageal cancer risk in patients with primary achalasia: a prospective study. Am J Gastroenterol. 2010;105(10):2144–9. https://doi.org/10.1038/ajg.2010.263.

    Article  CAS  PubMed  Google Scholar 

  12. Tustumi F, Bernardo WM, da Rocha JRM, et al. Esophageal achalasia: a risk factor for carcinoma. A systematic review and meta-analysis. Dis Esophagus. 2017;30(10):1–8. https://doi.org/10.1093/dote/dox072.

    Article  CAS  PubMed  Google Scholar 

  13. Stefanidis D, Richardson W, Farrell TM, Kohn GP, Augenstein V, Fanelli RD. SAGES guidelines for the surgical treatment of esophageal achalasia. Surg Endosc Other Interv Tech. 2012;26(2):296–311. https://doi.org/10.1007/s00464-011-2017-2.

    Article  Google Scholar 

  14. Yamaguchi D, Tsuruoka N, Sakata Y, Shimoda R, Fujimoto K, Iwakiri R. Safety and efficacy of botulinum toxin injection therapy for esophageal achalasia in Japan. J Clin Biochem Nutr. 2015;57(3):239–43. https://doi.org/10.3164/jcbn.15-47.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Inoue H, Sato H, Ikeda H, et al. Per-Oral endoscopic Myotomy: a series of 500 patients. J Am Coll Surg. 2015;221(2):256–64. https://doi.org/10.1016/j.jamcollsurg.2015.03.057.

    Article  PubMed  Google Scholar 

  16. Lopushinsky SR, Urbach DR. Pneumatic dilatation and surgical myotomy for achalasia. J Am Med Assoc. 2006;296(18):2227–33. https://doi.org/10.1001/jama.296.18.2227.

    Article  CAS  Google Scholar 

  17. Weber CE, Davis CS, Kramer HJ, Gibbs JT, Robles L, Fisichella PM. Medium and long-term outcomes after pneumatic dilation or laparoscopic heller myotomy for achalasia: a meta-analysis. Surg Laparosc Endosc Percutaneous Tech. 2012;22(4):289–96. https://doi.org/10.1097/SLE.0b013e31825a2478.

    Article  Google Scholar 

  18. Campos GM, Vittinghoff E, Rabl C, et al. Endoscopic and surgical treatments for achalasia: a systematic review and meta-analysis. Ann Surg. 2009;249(1):45–57. https://doi.org/10.1097/SLA.0b013e31818e43ab.

    Article  PubMed  Google Scholar 

  19. Schoenberg MB, Marx S, Kersten JF, et al. Laparoscopic Heller myotomy versus endoscopic balloon dilatation for the treatment of achalasia: a network meta-analysis. Ann Surg. 2013;258(6):943–52. https://doi.org/10.1097/SLA.0000000000000212.

    Article  PubMed  Google Scholar 

  20. Yaghoobi M, Mayrand S, Martel M, Roshan-Afshar I, Bijarchi R, Barkun A. Laparoscopic Heller’s myotomy versus pneumatic dilation in the treatment of idiopathic achalasia: a meta-analysis of randomized, controlled trials. Gastrointest Endosc. 2013;78(3):468–75. https://doi.org/10.1016/j.gie.2013.03.1335.

    Article  PubMed  Google Scholar 

  21. Patti MG, Andolfi C, Bowers SP, Soper NJ. POEM vs laparoscopic Heller Myotomy and fundoplication: which is now the gold standard for treatment of achalasia? J Gastrointest Surg. 2017;21(2):207–14. https://doi.org/10.1007/s11605-016-3310-0.

    Article  PubMed  Google Scholar 

  22. Zaninotto G, Costantini M, Rizzetto C, et al. Four hundred laparoscopic myotomies for esophageal achalasia a single centre experience. Ann Surg. 2008;248(6):986–93. https://doi.org/10.1097/SLA.0b013e3181907bdd.

    Article  PubMed  Google Scholar 

  23. SAGES. Quality of life outcomes after Heller Myotomy for achalasia comparing Dor and Toupet Fundoplications. https://www.sages.org/meetings/annual-meeting/abstracts-archive/quality-of-life-outcomes-after-heller-myotomy-for-achalasia-comparing-dor-and-toupet-fundoplications/.

  24. Wei MT, He YZ, Deng XB, et al. Is Dor fundoplication optimum after laparoscopic Heller myotomy for achalasia? A meta-analysis. World J Gastroenterol. 2013;19(43):7804–12. https://doi.org/10.3748/wjg.v19.i43.7804.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Andolfi C, Baffy G, Fisichella PM. Whose patient is it? The path to multidisciplinary management of achalasia. J Surg Res. 2018;228:8–13. https://doi.org/10.1016/j.jss.2018.02.047.

    Article  PubMed  Google Scholar 

  26. Pellegrini C, Wetter LA, Patti M, et al. Thoracoscopic esophagomyotomy. Initial experience with a new approach for the treatment of achalasia. Ann Surg. 1992;216(3):291–6; discussion 296–9. http://www.ncbi.nlm.nih.gov/pubmed/1417178.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Patti MG, Pellegrini CA, Horgan S, et al. Minimally invasive surgery for achalasia: an 8-year experience with 168 patients. Ann Surg. 1999;230(4):587–93; discussion 593–4. https://doi.org/10.1097/MPG.0b013e318032062f.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  28. Richards WO, Torquati A, Holzman MD, et al. Heller myotomy versus heller myotomy with dor fundoplication for achalasia: a prospective randomized double-blind clinical trial. Ann Surg. 2004;240(3):405–15. https://doi.org/10.1097/01.sla.0000136940.32255.51.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Rebecchi F, Allaix ME, Schlottmann F, Patti MGMM. Laparoscopic Heller myotomy and fundoplication: what is the evidence ? Am Surg. 2018;84(4):481–9. http://libproxy.lib.unc.edu/login?url=https://search.proquest.com/docview/2042209620?accountid=14244.

    PubMed  Google Scholar 

  30. Rawlings A, Soper NJ, Oelschlager B, et al. Laparoscopic Dor versus Toupet fundoplication following Heller myotomy for achalasia: results of a multicenter, prospective, randomized-controlled trial. Surg Endosc Other Interv Tech. 2012;26(1):18–26. https://doi.org/10.1007/s00464-011-1822-y.

    Article  Google Scholar 

  31. Tomasko JM, Augustin T, Tran TT, Haluck RS, Rogers AM, Lyn-Sue JR. Quality of life comparing Dor and Toupet after Heller Myotomy for achalasia. JSLS J Soc Laparoendosc Surg. 2014;18(3):e2014.00191. https://doi.org/10.4293/JSLS.2014.00191.

    Article  Google Scholar 

  32. Nissen R. A simple operation for control of reflux esophagitis. Schweiz Med Wochenschr. 1956;86(Suppl 20):590–2. http://www.ncbi.nlm.nih.gov/pubmed/13337262.

    CAS  PubMed  Google Scholar 

  33. Dor J, Humbert P, Dor V, Figarella J. L’interet de la technique de Nissen modifiee dans la prevention du reflux apres cardiomyotomie extramuqueuse de Heller. Mem Acad Chir. 1962;88:877–83.

    Google Scholar 

  34. Toupet A. Technique d’oesophago-gastroplastie avec phréno-gastropexie appliquée dans la cure radicale des hernies hiatales et comme complément de l’opération de Heller dans les cardiospasmes. Acad Chir. 1963;89:394–9.

    Google Scholar 

  35. Wang PC, Sharp KW, Holzman MD, Clements RH, Holcomb GW, Richards WO. The outcome of laparoscopic Heller myotomy without antireflux procedure in patients with achalasia. Am Surg. 1998;64(6):515–20; discussion 521. http://www.ncbi.nlm.nih.gov/pubmed/9619171.

    CAS  PubMed  Google Scholar 

  36. Diamantis T, Pikoulis E, Felekouras E, et al. Laparoscopic esophagomyotomy for achalasia without a complementary antireflux procedure. J Laparoendosc Adv Surg Tech. 2006;16(4):345–9. https://doi.org/10.1089/lap.2006.16.345.

    Article  Google Scholar 

  37. Falkenback D, Johansson J, Öberg S, et al. Heller’s esophagomyotomy with or without a 360° floppy Nissen fundoplication for achalasia. Long-term results from a prospective randomized study. Dis Esophagus. 2003;16(4):284–90. https://doi.org/10.1111/j.1442-2050.2003.00348.x.

    Article  CAS  PubMed  Google Scholar 

  38. Patti MG, Robinson T, Galvani C, et al. Total fundoplication is superior to partial fundoplication even when esophageal peristalsis is weak. J Am Coll Surg. 2004;198(6):863–70. https://doi.org/10.1016/j.jamcollsurg.2004.01.029.

    Article  PubMed  Google Scholar 

  39. Donahue PE, Schlesinger PK, Sluss KF, et al. Esophagocardiomyotomy–floppy Nissen fundoplication effectively treats achalasia without causing esophageal obstruction. Surgery. 1994;116(4):719–24; discussion 724–5. http://www.ncbi.nlm.nih.gov/pubmed/7940171.

    CAS  PubMed  Google Scholar 

  40. Patti MG, Herbella FA. Fundoplication after laparoscopic Heller Myotomy for esophageal achalasia: what type? J Gastrointest Surg. 2010;14(9):1453–8. https://doi.org/10.1007/s11605-010-1188-9.

    Article  PubMed  Google Scholar 

  41. Rebecchi F, Giaccone C, Farinella E, Campaci R, Morino M. Randomized controlled trial of laparoscopic heller myotomy plus dor fundoplication versus nissen fundoplication for achalasialong-term results. Ann Surg. 2008;248(6):1023–9. https://doi.org/10.1097/SLA.0b013e318190a776.

    Article  PubMed  Google Scholar 

  42. Topart P, Deschamps C, Taillefer R, Duranceau A. Long-term effect of total fundoplication on the myotomized esophagus. Ann Thorac Surg. 1992;54(6):1046–52. https://doi.org/10.1016/0003-4975(92)90068-F.

    Article  CAS  PubMed  Google Scholar 

  43. Rossetti G, Brusciano L, Amato G, et al. A total fundoplication is not an obstacle to esophageal emptying after heller myotomy for achalasia: results of a long-term follow up. Ann Surg. 2005;241(4):614–21. http://www.ncbi.nlm.nih.gov/pubmed/15798463.

    Article  PubMed  PubMed Central  Google Scholar 

  44. di Martino N, Brillantino A, Monaco L, et al. Laparoscopic calibrated total vs partial fundoplication following heller myotomy for oesophageal achalasia. World J Gastroenterol. 2011;17(29):3431–40. https://doi.org/10.3748/wjg.v17.i29.3431.

    Article  PubMed  PubMed Central  Google Scholar 

  45. Ortiz A, De Haro LFM, Parrilla P, et al. Very long-term objective evaluation of Heller myotomy plus posterior partial fundoplication in patients with achalasia of the cardia. Ann Surg. 2008;247(2):258–64. https://doi.org/10.1097/SLA.0b013e318159d7dd.

    Article  PubMed  Google Scholar 

  46. Kumagai K, Kjellin A, Tsai JA, et al. Toupet versus Dor as a procedure to prevent reflux after cardiomyotomy for achalasia: results of a randomised clinical trial. Int J Surg. 2014;12(7):673–80. https://doi.org/10.1016/j.ijsu.2014.05.077.

    Article  PubMed  Google Scholar 

  47. Kurian AA, Bhayani N, Sharata A, Reavis K, Dunst CM, Swanström LL. Partial anterior vs partial posterior fundoplication following transabdominal esophagocardiomyotomy for achalasia of the esophagus: meta-regression of objective postoperative gastroesophageal reflux and dysphagia. JAMA Surg. 2013;148(1):85–90. https://doi.org/10.1001/jamasurgery.2013.409.

    Article  PubMed  Google Scholar 

  48. Hunter JG, Trus TL, Branum GD, Waring JP. Laparoscopic Heller myotomy and fundoplication for achalasia. Ann Surg. 1997;225(6):655–64; discussion 664–5. http://www.ncbi.nlm.nih.gov/pubmed/9230806.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  49. Tatum RP, Pellegrini CA. How i do it: laparoscopic heller myotomy with toupet fundoplication for achalasia. J Gastrointest Surg. 2009;13(6):1120–4. https://doi.org/10.1007/s11605-008-0585-9.

    Article  PubMed  Google Scholar 

  50. Patti MG, Fisichella PM. Laparoscopic heller myotomy and dor fundoplication for esophageal achalasia. How i do it. J Gastrointest Surg. 2008;12(4):764–6. https://doi.org/10.1007/s11605-007-0368-8.

    Article  PubMed  Google Scholar 

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Farrell, T.M., Di Corpo, M., Patti, M.G. (2020). Laparoscopic Heller Myotomy and Posterior Partial Fundoplication. In: Patti, M., Di Corpo, M., Schlottmann, F. (eds) Foregut Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-27592-1_7

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