Abstract
The purpose of this chapter is to delineate the age-related degenerative changes of the spinal column, sacroiliac joints (SI), and hip joint. The spine has evolved to optimize locomotion by dispersing the associated forces throughout its elements and tissues, however, degeneration caused by repeated sprains, strains, and overuse can lead to painful conditions. Degenerative changes are progressive, irreversible, and often caused by aging and excessive usage. Degeneration of the spine imparts a large socioeconomic cost on the healthcare system. Understanding the pathophysiology of these degenerative changes is essential for targeting and treating the mechanisms of pain, rather than symptomatic treatment. In this chapter, we discuss the normal and pathological anatomy of the facet joints, sacroiliac joint, and hip joint; the primary focus is on the degenerative disease states associated with excess wear and tear and age-related degenerative changes.
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Agur AMR, Lee MJ, Grant JCB. Grant’s atlas of anatomy. Philadelphia: Lippincott Williams & Wilkins; 1999.
Selby DK, Paris SV. Anatomy of facet joints and its clinical correlation with low back pain. Contemp Orthop. 1981;3:1097–103.
Pal GP, Routal RV. Transmission of weight through the lower thoracic and lumbar regions of the vertebral column in man. J Anat. 1987;152:93–105.
Pal GP, Routal RV, Saggu SK. The orientation of the articular facets of the zygapophyseal joints at the cervical and upper thoracic region. J Anat. 2001;198(Pt 4):431–41.
Masharawi Y, Rothschild B, Dar G, Peleg S, Robinson D, Been E, et al. Facet orientation in the thoracolumbar spine: three-dimensional anatomic and biomechanical analysis. Spine. 2004;29:1755–63.
Slipman CW, Whyte WS 2nd, Chow DW, et al. Sacroiliac joint syndrome. Pain Physician. 2001;4:143–52.
Puhakka KB, Melsen F, Junk AG, Boel LW, Vesterby A, Egund N. MR imaging of the normal sacroiliac joint with correlation to histology. Skelet Radiol. 2004;33:15–28.
Jaumard NV, Welch WC, Winkelstein BA. Spinal facet joint biomechanics and mechanotransduction in normal, injury, and degenerative conditions. J Biomech Eng. 2011;133:070110.
Vernon-Roberts B, Pirie CJ. Degenerative changes in the intervertebral discs and their sequelae. Rheumatol Rehabil. 1977;16:1321.
Dunlop RB, Adams MA, Hutton WC. Disc space narrowing and the lumbar facet joints. J Bone Joint Surg. 1984;66:706–10.
Butler D, Trafimow JH, Andersson GBJ, McNeill TW, Huckman MS. Discs degenerate before facets. Spine. 1990;15:111–3.
Bywaters ECG. The pathological anatomy of idiopathic low back pain. In: White AA, Gordon S, editors. Symposium on idiopathic low back pain. St. Louis: CV Mosby; 1982. p. 144–75.
Coventry MB, Ghormley RK, Kernohan JW. The intervertebral disc: its microscopic anatomy and pathology. Part I. J Bone Joint Surg. 1945;27:105–12.
Covenentry MB, Ghormley RK, Kernohawn JW. The intervertebral disc: its microscopic anatomy and pathology. Part II. J Bone Joint Surg. 1945;27A:233–47.
Aarabi B, Walters BC, Dhall SS, Gelb DE, Hurlbert RJ, Rozzelle CJ, et al. Subaxial cervical spine surgery classification systems. Neurosurgery. 2013;72(Suppl 2):170–86.
Crawford NR, Duggal N, Chamberlain RH, Park SC, Sonntag VK, Dickman CA. Unilateral cervical facet dislocation: injury mechanism and biomechanical consequences. Spine. 2002;27:1858–64.
Dvorak MF, Fisher CG, Aarabi B, Harris MB, Hurbert RJ, Rampersaud YR, et al. Clinical outcomes of 90 isolated unilateral facet fractures, subluxations, and dislocations treated surgically and nonoperatively. Spine. 2007;32:3007–13.
Takigwa T, Espinoza Orias AA, An HS, Gohgi S, Udayakumar RK, Sugisaki K, et al. Spinal kinematics and facet load transmission after total disc replacement. Spine. 2010;35:E1160–6.
Raynor RB, Moskovich R, Zidel P, Pugh J. Alterations in primary and coupled neck motions after facetectomy. Neurosurgery. 1987;21:681–7.
Kallakuri S, Li Y, Chen C, Cavanaugh JM. Innervation of cervical ventral facet joint capsule: histological evidence. World J Orthop. 2012;3:10–4.
Zhou L, Schneck CD, Shao Z. The anatomy of the dorsal ramus nerves and its implications in low back pain. Neurosci Med. 2012;3:192–201.
Bogduk N, Long D. The anatomy of the so-called “articular nerves” and their relationship to facet denervation in the treatment of low back pain. J Neurosurg. 1979;51:172–7.
Hirsh C, Ingelmark B, Miller M. The anatomical basis for low back pain. Acta Othop Scand. 1963;33:1.
Gellhorn AC, Katz JN, Suri P. Osteoarthritis of the spine: the facet joints. Nat Rev Rheumatol. 2013;9:216–24.
Kim JS, Ali MH, Wydra F, Li X, Hamilton JL, An HS, et al. Characterization of degenerative human facet joints and facet joint capsular tissues. Osteoarthr Cartil. 2015;23:2242–51.
Kalichman L, Kim DH, Li X, Guermazi A, Hunter DJ. Computed tomography-evaluated features of spinal degeneration: prevalence, intercorrelation, and association with self-reported back pain. Spine J. 2010;10:200–8.
Borenstein D. Does osteoarthritis of the lumbar spine cause chronic low back pain. Curr Pain Headache Rep. 2004;8:512–7.
Hirsch C, Ingelmark BE, Miller M. The anatomical basis for low back pain: studies on the presence of sensory nerve endings in ligamentous, capsular, and intervertebral disc structures in the human lumbar spine. Act Orthop Scand. 1963;33:1–17.
Marks RC, Houston T, Thulbourne T. Facet joint injection and facet nerve block: a randomized comparison in 86 patients with chronic low back pain. Pain. 1992;49:325–8.
Mooney V, Robertson J. The facet syndrome. Clin Orthop Relat Res. 1976;115:149–56.
McCall IW, Park WM, O’Brien JP. Induced pain referral from posterior lumbar elements in normal subjects. Spine. 1979;4:441–6.
Schwarzer AC, Aprill CN, Derby R, Fortin J, Kine G, Bogduk N. Clinical features of patients with pain stemming from the lumbar zygapophyseal joints: is the lumbar facet syndrome a clinical entity? Spine. 1994;19:1132–7.
Schneck CD. The anatomy of lumbar spondylosis. Clin Orthop Relat Res. 1985;193:20–36.
Gibson JNA, Waddell G. Surgery for degenerative lumbar spondylosis. Spine. 2005;20:2312–20.
O’Neill TW, McCloskey EV, Kanis JA, Bhalla AK, Reeve J, Reid DM, et al. The distribution, determinants, and clinical correlates of vertebral osteophytosis: a population based survey. J Rheumatol. 1999;26:842–8.
Fitzgerald J, Newman PH. Degenerative spondylolisthesis. J Bone Joint Surg Br. 1976;58:184–92.
Esses SI, editor. Spondylolisthesis. In: Textbook of spinal disorders. Philadelphia: Lippincott Williams & Wilkins; 1995.
Friberg O. Instability in spondylolisthesis. Orthopedics. 1991;1:463–6.
Frymoyer JW. Degenerative spondylolisthesis: diagnosis and treatment. J Am Acad Orthop Surg. 1994;2:9–15.
Wiltse LL. The etiology of spondylolisthesis. Clin Orthop. 1957;10:48–58.
Wiltse LL. The etiology of spondylolisthesis. J Bone Joint Surg. 1962;4A:539–60.
Wiltse LL, Rothman SLG. Spondylolisthesis: classification, diagnosis and natural history. Semin Spine Surg. 1989;1:78–94.
Ensrud KE, Black DM, Harris F. Correlates of kyphosis in older women. The fracture Intervention Trial Research Group. J Am Geriatr Soc. 1997;45:682–7.
Tran TH, Wing D, Davis A, Bergstrom J, Schousboe JT, Nichols JF, et al. Correlations among four measures of thoracic kyphosis in older adults. Osteoporos Int. 2016;27(3):1255–9.
Kado DM, Huang MH, Karlamangla AS, Cawthon P, Katzman W, Hillier TA, et al. Factors associated with kyphosis progression in older women: 15 years’ experience in the study of osteoporotic fractures. J Bone Miner Res. 2013;28(1):179–87.
Sinaki M, Itoi E, Roger JW, Bergstralh EJ, Wahner HW. Correlation of back extensor strength with thoracic kyphosis and lumbar lordosis in estrogen-deficient women. Am J Phys Med Rehabil. 1996;75(5):370–4.
Kado DM, Miller-Martinez D, Lui LY. Hyperkyphosis, kyphosis progression, and risk of non-spine fractures in older community dwelling women: the study of osteoporotic fractures (SOF). J Bone Miner Res. 2014;29(10):2210–6.
Katzman WB, Miller-Martinez D, Marshall LM, Lane NE, Kado DM. Kyphosis and paraspinal muscle composition in older men: a cross-sectional study for the osteoporotic fractures in men (MrOS) research group. BMC Musculoskelet Disord. 2014;15:19.
Yamamoto J, Bergstrom J, Davis A, Wing D, Nichols J, Kado D. Trunk lean mass and its association with 3 measures of kyphosis in older dwelling persons. J Am Geriatr Soc. 2015;63(Suppl 1):S14.
Katzman WB, Harrison SL, Fink HA, Marshall LM, Orwoll E, Barrett-Connor E, et al. Physical function in older men with hyperkyphosis. J Gerontol A Biol Sci Med Sci. 2015;70(5):635–40.
Maigne JY, Aivaliklis A, Pfefer F. Results of sacroiliac joint double block and value of sacroiliac pain provocation test in 54 patients with low back pain. Spine. 1996;21:1889–92.
Schwarzer AC, April CN, Bogduk N. The sacroiliac joint in chronic low back pain. Spine. 1995;20:31–7.
Dreyfuss P, Dreyer SJ, Cole A, Mayo K. Sacroiliac joint pain. J Am Acad Orthop Surg. 2004;12:255–65.
Wyatt M, Underwood MR, Scheel IB, Cassidy JD, Nagel P. Back pain and health policy research: the what, why, how, who, and when. Spine (Phila Pa 1976). 2004;29:468–75.
Diamond S, Borenstein D. Chronic low back pain in working-age adult. Best Pract Res Clin Rheumatol. 2006;20:707–20.
Strine TW, Hootman JM. US national prevalence of correlates of low back and neck pain among adults. Arthritis Rheum. 2007;57:656–65.
Deyo RA, Weinstein JN. Low back pain. N Engl J Med. 2001;344:363–70.
Sturresson B, Selvik G, Uden A. Movements of the sacroiliac joints: a roentgen stereophotogrammetric analysis. Spine. 1989;14:162–5.
Ikeda R. Innervation of the sacroiliac joint: macroscopical and histological studies. Nippon Ika Daigaku Zasshi. 1991;58:587–96.
Fortin JD, Kissling RO, O’Connor BL, Vilensky JA. Sacroiliac joint innervation and pain. Am J Orthop. 1999;28:687–90.
Grob KR, Neuhuber WL, Kissling RO. Innervation of the sacroiliac joint of the human. Z Rheumatol. 1995;54:117–22.
Patel N, Gross A, Brown L, Gekht G. A randomized, placebo-controlled study to assess the efficacy of lateral branch neurotomy for chronic sacroiliac joint pain. Pain Med. 2012;13:383–98.
Vleeming A. The sacroiliac joint: a clinical anatomical biomechanical and radiological study. Thesis, Erasmus University Rotterdam: Rotterdam; 1990.
Calvillo O, Skaribas I, Turnipseed J. Anatomy and pathophysiology of the sacroiliac joint. Curr Rev Pain. 2000;4(5):356–61.
Onsel C, Collier BD, Kir KM, Larson SJ, Meyer GA, Krasnow AZ, et al. Increased sacroiliac joint uptake after lumbar fusion and or laminectomy. Clin Nucl Med. 1992;17(4):283–7.
Vleeming A, Schuenke MD, Masi AT, Carreiro JE, Danneels L, Willard FH. The sacroiliac joint: an overview of its anatomy, function, and potential clinical implications. J Anat. 2012;221:1469–80.
Molini L, Precerutti M, Gervasio A, Draghi F, Bianchi S. Hip: anatomy and US technique. J Ultrasound. 2011;14:99–108.
Jesse M, Petersen B, Strickland C, Mei-Dan O. Normal anatomy and imaging of the hip: emphasis on impingement assessment. Semin Musculoskelet Radiol. 2013;17(03):229–47.
Rodeo SA, Hannafin JA, Tom J, Warren RF, Wickiewicz TL. Immunolocalization of cytokines and their receptors in adhesive capsulitis of the shoulder. J Orthop Res. 1997;15(3):427–36.
Lane NE. Clinical practice. Osteoarthritis of the hip. N Engl J Med. 2007;357(14):1413–21.
Hamilton HW, Jamison J. The classification of degenerative hip disease. J Bone Joint Surg Br. 2012;94b:1193–201.
Lespasio MJ, Sultan AA, Piuzzi NS, Khlopas A, Husni ME, Muschler GF, et al. Hip osteoarthritis: a primer. Perm J. 2018;22:17–084.
Murphy NJ. Hip osteoarthritis: etiopathogenesis and implications for management. Adv Ther. 2016;33:1921–46.
Riviere C, Lazic S, Dagneaux L, Van Der Straeten C, Cobb J, Muirhead-Allwood S. Spine-hip relations in patients with hip osteoarthritis. EFORT Open Rev. 2018;3(2):39–44.
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Qian, S., Sengupta, V., Francis, J.K. (2020). Degenerative Spine Joint Disease. In: Mao, J. (eds) Spine Pain Care. Springer, Cham. https://doi.org/10.1007/978-3-030-27447-4_13
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DOI: https://doi.org/10.1007/978-3-030-27447-4_13
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