Abstract
This chapter focuses on the definition of dyslexia as “neurobiological in origin” as prescribed by the International Dyslexia Association and National Institute of Child Health and Human Development. The chapter examines the notion of dyslexia as a specific learning disability and challenges the presumption that impairments are specific or limited to reading behavior based on behavioral and neurobiological evidence. The authors argue that the convergence of evidence from neuroimaging studies leading up to the adoption of the definition of dyslexia in 2003 is belied by a larger set of more divergent findings suggesting a variety of etiologies of the disorder. Moreover, the argument for a central phonological deficit behaviorally with neurobiological impairments in regions associated with receptive language processing (roughly surrounding Wernicke’s area) may be just as much an outcome determined by multiple sources of lower-level impairments as it is a cause of dyslexia. Familial risk factors of the disorder are reflected in brain development, and behavior and evidence of genetic markers suggest a certain degree of heritability. However, clear evidence for environmental mediators and successful interventions yields a complex dynamic of how nature and nurture interact in the emergence of the disorder. Thus, this likely equifinality of the disorder requires that large datasets of neurobiological and behavioral data be culled to uncover endophenotypic subtypes or biotypes of dyslexia that may reflect differential responses to intervention.
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Notes
- 1.
Despite nominal disputes in the literature, we use the terms developmental dyslexia, dyslexia, reading impairment, reading disorder, and reading disability interchangeably in this chapter.
- 2.
For the purposes of this chapter, and to avoid the potential confusion of anatomical labels, we will use more commonly recognized terminology, including Wernicke’s area, and Broca’s area, as well as VWFA. However, it should be noted that these labels which refer to a region’s function are sources of debate as the putative structure–function relationships have become less well defined.
- 3.
A gene deletion or mutation is when DNA or part of a chromosome does not replicate when the gene is passed on.
References
Ahissar, M. (2007). Dyslexia and the anchoring-deficit hypothesis. Trends in Cognitive Sciences, 11(11), 458–465. https://doi.org/10.1016/j.tics.2007.08.015.
Alexander-Passe, N. (2006). How dyslexic teenagers cope: An investigation of self-esteem, coping and depression. Dyslexia, 12(4), 256–275. https://doi.org/10.1002/dys.318.
Asbury, K., Wachs, T. D., & Plomin, R. (2005). Environmental moderators of genetic influence on verbal and nonverbal abilities in early childhood. Intelligence, 33(6), 643–661. https://doi.org/10.1016/j.intell.2005.03.008.
Aylward, E. H., Richards, T. L., Berninger, V. W., Nagy, W. E., Field, K. M., Grimme, A. C., et al. (2003). Instructional treatment associated with changes in brain activation in children with dyslexia. Neurology, 61(2), 212–219.
Banai, K., Hornickel, J., Skoe, E., Nicol, T., Zecker, S., & Kraus, N. (2009). Reading and subcortical auditory function. Cerebral Cortex, 19(11), 2699–2707. https://doi.org/10.1093/cercor/bhp024.
Beaulieu, C., Plewes, C., Paulson, L. A., Roy, D., Snook, L., Concha, L., et al. (2005). Imaging brain connectivity in children with diverse reading ability. NeuroImage, 25(4), 1266–1271. https://doi.org/10.1016/j.neuroimage.2004.12.053.
Ben-Yehudah, G., & Ahissar, M. (2004). Sequential spatial frequency discrimination is consistently impaired among adult dyslexics. Vision Research, 44(10), 1047–1063. https://doi.org/10.1016/j.visres.2003.12.001.
Black, J. M., Tanaka, H., Stanley, L., Nagamine, M., Zakerani, N., Thurston, A., … Hoeft, F. (2012). Maternal history of reading difficulty is associated with reduced language-related gray matter in beginning readers. NeuroImage, 59(3), 3021–3032. https://doi.org/10.1016/j.neuroimage.2011.10.024.
Bolger, D. J., Hornickel, J., Cone, N. E., Burman, D. D., & Booth, J. R. (2008a). Neural correlates of orthographic and phonological consistency effects in children. Human Brain Mapping, 29(12), 1416–1429.
Bolger, D. J., Minas, J., Burman, D. D., & Booth, J. R. (2008b). Differential effects of orthographic and phonological consistency in cortex for children with and without reading impairment. Neuropsychologia, 46(14), 3210–3224. https://doi.org/10.1016/j.neuropsychologia.2008.07.024.
Bolger, D. J., Perfetti, C. A., & Schneider, W. (2005). Cross-cultural effect on the brain revisited: Universal structures plus writing system variation. Human Brain Mapping, 25, 92–104. https://doi.org/10.1002/hbm.20124.
Brambati, S. M., Termine, C., Ruffino, M., Stella, G., Fazio, F., Cappa, S. F., et al. (2004). Regional reductions of gray matter volume in familial dyslexia. Neurology, 63(4), 742–745. https://doi.org/10.1212/01.WNL.0000134673.95020.EE.
Brown, W., Eliez, S., Menon, V., Rumsey, J., White, C., & Reiss, A. (2001). Preliminary evidence of widespread morphological variations of the brain in dyslexia. Neurology, 56(6), 781–783. https://doi.org/10.1212/wnl.56.6.781.
Brunswick, N., McCrory, E., Price, C. J., Frith, C. D., & Frith, U. (1999). Explicit and implicit processing of words and pseudowords by adult developmental dyslexics. A search for Wernicke’s Wortschatz? Brain, 122(10), 1901–1917. https://doi.org/10.1093/brain/122.10.1901.
Cao, F., Bitan, T., & Booth, J. R. (2008). Effective brain connectivity in children with reading difficulties during phonological processing. Brain and Language, 107(2), 91–101.
Cao, F., Bitan, T., Chou, T. L., Burman, D. D., & Booth, J. R. (2006). Deficient orthographic and phonological representations in children with dyslexia revealed by brain activation patterns. Journal of Child Psychology and Psychiatry and Allied Disciplines, 47(10), 1041–1050. https://doi.org/10.1111/j.1469-7610.2006.01684.x
Catani, M., & Mesulam, M. (2008). The arcuate fasciculus and the disconnection theme in language and aphasia: History and current state. Cortex, 44(8), 953–961. https://doi.org/10.1016/j.cortex.2008.04.002.
Centanni, T., Booker, A. B., Chen, F., Sloan, A. M., Carraway, R. S., Rennaker, R. L., … Kilgard, M. P. (2016). Knockdown of dyslexia-gene DCDC2 interferes with speech sound discrimination in continuous streams. Journal of Neuroscience, 36(17), 4895–4906. https://doi.org/10.1523/jneurosci.4202-15.2016.
Centanni, T., Chen, F., Booker, A. M., Engineer, C. T., Sloan, A. M., Rennaker, R. L., … Kilgard, M. P. (2014). Speech sound processing deficits and training-induced neural plasticity in rats with dyslexia gene knockdown. PLoS ONE, 9(5). https://doi.org/10.1371/journal.pone.0098439.
Chandrasekaran, B., Hornickel, J., Skoe, E., Nicol, T., & Kraus, N. (2009). Context-dependent encoding in the human auditory brainstem relates to hearing speech in noise: Implications for developmental dyslexia. Neuron, 64(3), 311–319. https://doi.org/10.1016/j.neuron.2009.10.006.
Cicchini, G. M., Marino, C., Mascheretti, S., Perani, D., & Morrone, M. C. (2015). Strong motion deficits in dyslexia associated with DCDC2 gene alteration. Journal of Neuroscience, 35(21), 8059–8064.
Clark, K. A., Helland, T., Specht, K., Narr, K. L., Manis, F. R., Toga, A. W., et al. (2014). Neuroanatomical precursors of dyslexia identified from pre-reading through to age 11. Brain, 137(12), 3136–3141. https://doi.org/10.1093/brain/awu229.
Connor, C. M., Piasta, S. B., Fishman, B., Glasney, S., Schatschneider, C., Crowe, E., … Morrison, F. J. (2009). Individualizing student instruction precisely: Effects of child × instruction interactions on first graders’ literacy development. Child Development, 80(1), 77–100. https://doi.org/10.1111/j.1467-8624.2008.01247.x.
Darki, F., Peyrard-Janvid, M., Matsson, H., Kere, J., & Klingberg, T. (2012). Three dyslexia susceptibility genes, DYX1C1, DCDC2, and KIAA0319, affect temporo-parietal white matter structure. Biological Psychiatry, 72(8), 671–676. https://doi.org/10.1016/j.biopsych.2012.05.008.
Davis, N., Barquero, L., Compton, D. L., Fuchs, L. S., Fuchs, D., Gore, J. C., et al. (2011). Functional correlates of children’s responsiveness to intervention. Developmental Neuropsychology, 36(3), 288–301.
Dawson, G., Finley, C., Phillips, S., & Galpert, L. (1986). Hemispheric specialization and the language abilities of autistic children. Society for Research in Child Development, 57(6), 1440–1453.
Debska, A., Łuniewska, M., Chyl, K., Banaszkiewicz, A., Zelechowska, A., Wypych, M., … Jednoróg, K. (2016). Neural basis of phonological awareness in beginning readers with familial risk of dyslexia-Results from shallow orthography. NeuroImage, 132, 406–416. https://doi.org/10.1016/j.neuroimage.2016.02.063.
Dejerine, M., & Symes, W. L. (1893). Some recent papers on neurophysiology. Brain, 16(1–2), 318–320.
Demb, J. B., Boynton, G. M., Best, M., & Heeger, D. J. (1998). Psychophysical evidence for a magnocellular pathway deficit in dyslexia. Vision Research, 38(11), 1555–1559. https://doi.org/10.1016/s0042-6989(98)00075-3.
Desroches, A. S., Cone, N. E., Bolger, D. J., Bitan, T., Burman, D. D., & Booth, J. R. (2010). Children with reading difficulties show differences in brain regions associated with orthographic processing during spoken language processing. Brain Research, 1356, 73–84.
Deutsch, G. K., Dougherty, R. F., Bammer, R., Siok, W. T., Gabrieli, J. D. E., & Wandell, B. (2005). Children’s reading performance is correlated with white matter structure measured by diffusion tensor imaging. Cortex, 41(3), 354–363. https://doi.org/10.1016/s0010-9452(08)70272-7.
Drysdale, A. T., Grosenick, L., Downar, J., Dunlop, K., Mansouri, F., Meng, Y., … & Schatzberg, A. F. (2017). Resting-state connectivity biomarkers define neurophysiological subtypes of depression. Nature medicine, 23(1), 28.
Eckert, M. A., Vaden, Jr., K. I., Gebregziabher, M., & Dyslexia Data Consortium. (2018). Reading profiles in multi-site data with missingness. Frontiers in Psychology, 9, 644.
Eden, G. F., Jones, K. M., Cappell, K., Gareau, L., Wood, F. B., Zeffiro, T. A., … & Flowers, D. L. (2004). Neural changes following remediation in adult developmental dyslexia. Neuron, 44(3), 411–422.
Eden, G. F., VanMeter, J. W., Rumsey, J. M., Maisog, J. M., Woods, R. P., & Zeffiro, T. A. (1996). Abnormal processing of visual motion in dyslexia revealed by functional brain imaging. Nature, 382, 66–69. https://doi.org/10.1038/382066a0.
Elliott, J. G., & Gibbs, S. (2008). Does dyslexia exist? Journal of Philosophy of Education, 42(3–4), 475–491. https://doi.org/10.1111/j.1467-9752.2008.00653.x.
Facoetti, A., Corradi, N., Ruffino, M., Gori, S., & Zorzi, M. (2010a). Visual spatial attention and speech segmentation are both impaired in preschoolers at familial risk for developmental dyslexia. Dyslexia, 16(3), 226–239. https://doi.org/10.1002/dys.413.
Facoetti, A., & Molteni, M. (2001). The gradient of visual attention in developmental dyslexia. Neuropsychologia, 39(4), 352–357. https://doi.org/10.1016/S0028-3932(00)00138-X.
Facoetti, A., Pagnoni, G., Turatto, M., Marzola, V., & Mascetti, G. (2000). Visual-spatial attention in developmental dyslexia. Cortex, 36(1), 109–123. https://doi.org/10.1016/s0010-9452(08)70840-2.
Facoetti, A., Trussardi, A. N., Ruffino, M., Lorusso, M. L., Cattaneo, C., Galli, R., … Zorzi, M. (2010). Multisensory spatial attention deficits are predictive of phonological decoding skills in developmental dyslexia. Journal of Cognitive Neuroscience, 22(5), 1011–1025. https://doi.org/10.1162/jocn.2009.21232.
Facoetti, A., Zorzi, M., Cestnick, L., Lorusso, M. L., Molteni, M., Paganoni, P., … Mascetti, G. G. (2006). The relationship between visuo-spatial attention and nonword reading in developmental dyslexia. Cognitive Neuropsychology, 23(6), 841–855. https://doi.org/10.1080/02643290500483090.
Fletcher, J. M. (2005). Predicting math outcomes: Reading predictors and comorbidity. Journal of Learning Disabilities, 38(4), 308–312.
Fletcher, J. M., Lyon, G. R., Fuchs, L. S., & Barnes, M. A. (2018). Learning disabilities: From identification to intervention. Guilford Publications.
Fletcher, J. M., & Morris, R. (1986). Classification of disabled learners: Beyond exclusionary definitions. Handbook of cognitive, social, and neuropsychological aspects of learning disabilities, 1, 55–80.
Francis, D. J., Stuebing, K. K., Shaywitz, S. E., Shaywitz, B. A., & Fletcher, J. M. (1996). Developmental lag versus deficit models of reading disability: A longitudinal individual growth curves analysis. Journal of Educational Psychology, 88(1), 3–17.
Fuchs, L. S., & Fuchs, D. (2002). Mathematical problem-solving profiles of students with mathematics disabilities with and without comorbid reading disabilities. Journal of learning disabilities, 35(6), 564–574.
Gaab, N., Gabrieli, J. D. E., Deutsch, G. K., Tallal, P., & Temple, E. (2007). Neural correlates of rapid auditory processing are disrupted in children with developmental dyslexia and ameliorated with training: An fMRI study. Restorative Neurology and Neuroscience, 25(3–4), 295–310.
Gabrieli, J. D. E. (2009). Dyslexia: A new synergy between education and cognitive neuroscience. Science (New York, NY), 325(5938), 280–283. https://doi.org/10.1126/science.1171999.
Galaburda, A. M., & Kemper, T. L. (1979). Cytoarchitectonic abnormalities in developmental dyslexia: A case study. Annals of Neurology, 6(2), 94–100. https://doi.org/10.1002/ana.410060203.
Galaburda, A. M., & Livingstone, M. (1993). Evidence for a magnocellular defect in developmental dyslexia. Annals of the New York Academy of Sciences, 682(1), 70–82. https://doi.org/10.1111/j.1749-6632.1993.tb22960.x.
Galaburda, A. M., LoTurco, J., Ramus, F., Fitch, R. H., & Rosen, G. D. (2006). From genes to behavior in developmental dyslexia. Nature Neuroscience, 9(10), 1213–1217. https://doi.org/10.1038/nn1772.
Galaburda, A. M., Sanides, F., & Geschwind, N. (1978). Human brain. Cytoarchitectonic left-right asymmetries in the temporal speech region. Archives of Neurology, 35(12), 812–817.
Galaburda, A. M., Sherman, G. F., Rosen, G. D., Aboitiz, F., & Geschwind, N. (1985). Developmental dyslexia: Four consecutive patients with cortical anomalies. Annals of Neurology, 18(2), 222–233. https://doi.org/10.1002/ana.410180210.
Gathercole, S. E., Alloway, T. P., Willis, C., & Adams, A. M. (2006). Working memory in children with reading disabilities. Journal of Experimental Child Psychology, 93(3), 265–281.
Georgiewa, P., Rzanny, R., Hopf, J. M., Knab, R., Glauche, V., Kaiser, W. A., & Blanz, B. (1999). fMRI during word processing in dyslexic and normal reading children. Neuroreport, 10(16), 3459–65 (10599862).
Geschwind, N. (1970). The organization of language and the brain. Science, 170(961), 940–944. https://doi.org/10.1126/science.170.3961.940.
Geschwind, N. (1974). Selected papers on language and the brain (Vol. 16). Dordrecht: Springer, Netherlands. https://doi.org/10.1007/978-94-010-2093-0.
Gialluisi, A., Newbury, D. F., Wilcutt, E. G., Consortium, T. S. L. I., & Luciano, M. (2014). Genome-wide screening for DNA variants associated with reading and language traits. Genes, Brain and Behavior, 13(7), 686–701. https://doi.org/10.1111/gbb.12158.
Graves, W. W., Desai, R., Humphries, C., Seidenberg, M. S., & Binder, J. R. (2010). Neural systems for reading aloud: a multiparametric approach. Cerebral Cortex, 20(8), 1799–1815. https://doi.org/10.1093/cercor/bhp245.
Grigorenko, E. L. (2004). Genetic bases of developmental dyslexia: A capsule review of heritability estimates. Enfance, 56(3), 273–288. https://doi.org/10.3917/enf.563.0273.
Grigorenko, E. L. (2005). A conservative meta-analysis of linkage and linkage-association studies of developmental dyslexia. Scientific Studies of Reading, 9(3), 285–316. https://doi.org/10.1207/s1532799xssr0903.
Grigorenko, E. L., Naples, A., Chang, J., Romano, C., Ngorosho, D., Kungulilo, S., … Bundy, D. (2007). Back to Africa: Tracing dyslexia genes in East Africa. Reading and Writing: An Interdisciplinary Journal, 20(1–2), 27–49. https://doi.org/10.1007/s11145-006-9017-y.
Guttorm, T., Leppanen, P. H. T., Hamalainen, J. A., Eklund, K. M., & Lyytinen, H. J. (2010). Newborn event-related potentials predict poorer pre-reading skills in children at risk for dyslexia. Journal of Learning Disabilities, 43(5), 391–401. https://doi.org/10.1177/0022219409345005.
Guttorm, T., Leppanen, P., Poikkeus, A., Eklund, K., Lyytinen, P., & Lyytinen, H. (2005). Brain event-related potentials (ERPs) measured at birth predict later language development in children with and without familial risk for dyslexia. Cortex, 41(3), 291–303. https://doi.org/10.1016/S0010-9452(08)70267-3.
Guttorm, T., Leppanen, P. H. T., Richardson, U., & Lyytinen, H. (2001). Event-related potentials and consonant differentiation in newborns with familial risk for dyslexia. Journal of Learning Disabilities, 34(6), 534–544. https://doi.org/10.1177/002221940103400606.
Hämäläinen, J. A., Salminen, H. K., & Leppänen, P. H. T. (2013). Basic auditory processing deficits in dyslexia: Systematic review of the behavioral and event-related potential/ field evidence. Journal of Learning Disabilities, 46(5), 413–427. https://doi.org/10.1177/0022219411436213.
Hampshire, A., Highfield, R. R., Parkin, B. L., & Owen, A. M. (2012). Fractionating human intelligence. Neuron, 76(6), 1225–1237.
Harlaar, N., Butcher, L. M., Meaburn, E., Sham, P., Craig, I. W., & Plomin, R. (2005). A behavioural genomic analysis of DNA markers associated with general cognitive ability in 7-year-olds. Journal of Child Psychology and Psychiatry and Allied Disciplines, 46(10), 1097–1107. https://doi.org/10.1111/j.1469-7610.2005.01515.x.
Hart, S. A., Soden, B., Johnson, W., Schatschneider, C., & Taylor, J. (2013). Expanding the environment: Gene × school-level SES interaction on reading comprehension. Journal of Child Psychology and Psychiatry, 54(10), 1047–1055. https://doi.org/10.1111/jcpp.12083.
Heibert, E. H., & Taylor, B. M. (2000). Beginning reading instruction: Research on early interventions. In M. L. Kamil, P. B. Mosenthal, P. David Pearson, & R. Barr (Eds.), Handbook of reading research, Vol. III (pp. 455–482). Mahwah NJ: Lawrence Erlbaum.
Heim, S., Grande, M., Pape-Neumann, J., van Ermingen, M., Meffert, E., Grabowska, A., … Amunts, K. (2010). Interaction of phonological awareness and “magnocellular” processing during normal and dyslexic reading: behavioural and fMRI investigations. Dyslexia, 16(3), 258–282. https://doi.org/10.1002/dys.
Hoeft, F., Hernandez, A., McMillon, G., Taylor-Hill, H., Martindale, J. L., Meyler, A., … Gabrieli, J. D. E. (2006). Neural basis of dyslexia: A comparison between dyslexic and nondyslexic children equated for reading ability. Journal of Neuroscience, 26(42), 10700–10708. https://doi.org/10.1523/jneurosci.4931-05.2006.
Hoeft, F., McCandliss, B. D., Black, J. M., Gantman, A., Zakerani, N., Hulme, C., … & Gabrieli, J. D. (2011). Neural systems predicting long-term outcome in dyslexia. Proceedings of the National Academy of Sciences, 108(1), 361–366.
Hornickel, J., & Kraus, N. (2013). Unstable representation of sound: A biological marker of dyslexia. Journal of Neuroscience, 33(8), 3500–3504. https://doi.org/10.1523/JNEUROSCI.4205-12.2013.
Hosseini, S. M. H., Black, J. M., Soriano, T., Bugescu, N., Martinez, R., Raman, M. M., … Hoeft, F. (2013). Topological properties of large-scale structural brain networks in children with familial risk for reading difficulties. NeuroImage, 71, 260–274. https://doi.org/10.1016/j.neuroimage.2013.01.013.
Hus, Y. (2001). Early reading for low-ses minority language children: An attempt to “catch them before they fall”. Folia Phoniatrica et Logopaedica, 53(3), 173–182.
Hutzler, F., Kronbichler, M., Jacobs, A. M., & Wimmer, H. (2006). Perhaps correlational but not causal: No effect of dyslexic readers’ magnocellular system on their eye movements during reading. Neuropsychologia, 44(4), 637–648. https://doi.org/10.1016/j.neuropsychologia.2005.06.006.
Im, K., Raschle, N. M., Smith, S. A., Ellen Grant, P., & Gaab, N. (2016). Atypical sulcal pattern in children with developmental dyslexia and at-risk kindergarteners. Cerebral Cortex, 26(3), 1138–1148. https://doi.org/10.1093/cercor/bhu305.
Johannes, S., Kussmaul, C. L., Münte, T. F., & Mangun, G. R. (1996). Developmental dyslexia: Passive visual stimulation provides no evidence for a magnocellular processing defect. Neuropsychologia, 34(11), 1123–1127. https://doi.org/10.1016/0028-3932(96)00026-7.
Karmiloff-Smith, A. (2009). Nativism versus neuroconstructivism: Rethinking the study of developmental disorders. Developmental Psychology, 45(1), 56–63. https://doi.org/10.1037/a0014506.
Keller, T. A., & Just, M. A. (2009). Altering cortical connectivity: Remediation-induced changes in the white matter of poor readers. Neuron, 64(5), 624–631.
Krafnick, A. J., Flowers, D. L., Luetje, M. M., Napoliello, E. M., & Eden, G. F. (2014). An investigation into the origin of anatomical differences in dyslexia. The Journal of Neuroscience, 34(3), 901–908. https://doi.org/10.1523/JNEUROSCI.2092-13.2013.
Kronbichler, M., Hutzler, F., Staffen, W., Mair, A., Ladurner, G., & Wimmer, H. (2006). Evidence for a dysfunction of left posterior reading areas in German dyslexic readers. Neuropsychologia, 44(10), 1822–1832. https://doi.org/10.1016/j.neuropsychologia.2006.03.010.
Kronbichler, M., Wimmer, H., Staffen, W., Hutzler, F., Mair, A., & Ladurner, G. (2008). Developmental dyslexia: Gray matter abnormalities in the occipitotemporal cortex. Human Brain Mapping, 29(5), 613–625. https://doi.org/10.1002/hbm.20425.
Langer, N., Peysakhovich, B., Zuk, J., Drottar, M., Sliva, D. D., Smith, S., … Gaab, N. (2015). White matter alterations in infants at risk for developmental dyslexia. Cerebral Cortex, 27(2):1027–1036. https://doi.org/10.1093/cercor/bhv281.
Leppänen, P. H. T., Hämäläinen, J. A., Guttorm, T., Eklund, K. M., Salminen, H. K., Tanskanen, A., … Lyytinen, H. J. (2012). Infant brain responses associated with reading-related skills before school and at school age. Neurophysiologie Clinique/Clinical Neurophysiology, 42(1–2), 35–41. https://doi.org/10.1016/j.neucli.2011.08.005.
Leppänen, P. H. T., Hämäläinen, J. A., Salminen, H. K., Eklund, K. M., Guttorm, T. K., Lohvansuu, K., … Lyytinen, H. (2010). Newborn brain event-related potentials revealing atypical processing of sound frequency and the subsequent association with later literacy skills in children with familial dyslexia. Cortex, 46(10), 1362–1376. https://doi.org/10.1016/j.cortex.2010.06.003.
Lilienfeld, S. O., & Treadway, M. T. (2016). Clashing diagnostic approaches: DSM-ICD versus RDoC. Annual Review of Clinical Psychology, 12, 435–463.
Linkersdörfer, J., Jurcoane, A., Lindberg, S., Kaiser, J., Hasslehorn, M., Fiebach, C. J., et al. (2014). The association between gray matter volume and reading proficiency: A longitudinal study of beginning readers. Journal of Cognitive Neuroscience, 27(2), 308–318. https://doi.org/10.1162/jocn.
Linkersdörfer, J., Lonnemann, J., Lindberg, S., Hasselhorn, M., & Fiebach, C. J. (2012). Grey matter alterations co-localize with functional abnormalities in developmental dyslexia: An ALE meta-analysis. PLoS ONE, 7(8). https://doi.org/10.1371/journal.pone.0043122.
Livingstone, M. S., & Hubel, D. (1988). Segregation of form, color, movement, and depth: Anatomy, physiology, and perception. Science, 240(4853), 740–749. https://doi.org/10.1126/science.3283936.
Logan, J. A., Hart, S. A., Cutting, L., Deater-Deckard, K., Schatschneider, C., & Petrill, S. (2014). Reading development in young children: Genetic and environmental influences. Child Development, 84(6), 2131–2144. https://doi.org/10.1111/cdev.12104.
Lyon, G. R., Fletcher, J. M., Shaywitz, S. E., Shaywitz, B. A., Torgesen, J. K., Wood, F. B., … & Olson, R. (2001). Rethinking learning disabilities. Rethinking Special Education for a New Century, 259–287.
Lyon, G. R., Shaywitz, S. E., & Shaywitz, B. A. (2003). A definition of dyslexia. Annals of Dyslexia, 53(1), 1–14. https://doi.org/10.1007/s11881-003-0001-9.
Lyytinen, H., Guttorm, T., Huttunen, T., Hamalainen, J., Leppanen, P., & Vesterinen, M. (2005). Psychophysiology of developmental dyslexia: a review of findings including studies of children at risk for dyslexia. Journal of Neurolinguistics, 18(2), 167–195. https://doi.org/10.1016/j.jneuroling.2004.11.001.
Maisog, J. M., Einbinder, E. R., Flowers, D. L., Turkeltaub, P. E., & Eden, G. F. (2008). A meta-analysis of functional neuroimaging studies of dyslexia. Annals of the New York Academy of Sciences, 1145(1), 237–259.
Marinković, K. (2004). Spatiotemporal dynamics of word processing in the human cortex. The Neuroscientist, 10(2), 142–152. https://doi.org/10.1177/1073858403261018.
Marinković, K., Dhond, R. P., Dale, A. M., Glessner, M., Carr, V., & Halgren, E. (2003). Spatiotemporal dynamics of modality-specific and supramodal word processing. Neuron, 38(3), 487–497.
McCrory, E. J., Mechelli, A., Frith, U., & Price, C. J. (2005). More than words: A common neural basis for reading and naming deficits in developmental dyslexia? Brain, 128(2), 261–267. https://doi.org/10.1093/brain/awh340.
McDonald, C. R., Thesen, T., Carlson, C., Blumberg, M., Girard, H. M., Trongnetrpunya, A., … Halgren, E. (2010). Multimodal imaging of repetition priming: Using fMRI, MEG, and intracranial EEG to reveal spatiotemporal profiles of word processing. NeuroImage, 53(2), 707–717. https://doi.org/10.1016/j.neuroimage.2010.06.069.
McGuinness, C., McGuinness, D., & McGuinness, G. (1996). Phono-graphix TM: A new method for remediating reading difficulties. Annals of Dyslexia, 46(1), 73–96.
Meng, H., Powers, N. R., Tang, L., Cope, N. A., Zhang, P. X., Fuleihan, R., … & Gruen, J. R. (2011). A dyslexia-associated variant in DCDC2 changes gene expression. Behavior Genetics, 41(1), 58–66.
Meng, H., Smith, S. D., Hager, K., Held, M., Liu, J., Olson, R. K., … Gruen, J. R. (2005). DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proceedings of the National Academy of Sciences, 102(47), 17053–8. https://doi.org/10.1073/pnas.0508591102.
Meyler, A., Keller, T. A., Cherkassky, V. L., Gabrieli, J. D. E., & Just, M. A. (2008). Modifying the brain activation of poor readers during sentence comprehension with extended remedial instruction: A longitudinal study of neuroplasticity. Neuropsychologia, 46(10), 2580–2592.
Milne, E., & Grafman, J. (2001). Ventromedial prefrontal cortex lesions in humans eliminate implicit gender stereotyping. The Journal of Neuroscience, 21(12), RC150.
Milne, R. D., Syngeniotis, A., Jackson, G., & Corballis, M. C. (2002). Mixed lateralization of phonological assembly in developmental dyslexia. Neurocase, 8(3), 205–209. https://doi.org/10.1093/neucas/8.3.205.
Molfese, D. L. (2000). Predicting dyslexia at 8 years of age using neonatal brain responses. Brain and Language, 72(3), 238–245. https://doi.org/10.1006/brln.2000.2287.
Molfese, D. L., & Molfese, V. J. (1985). Electrophysiological indices of auditory discrimination in newborn infants: The bases for predicting later language development? Infant Behavior and Development, 9(2), 197–211.
Molfese, D. L., & Molfese, V. J. (1997). Discrimination of language skills at five years of age using event-related potentials recorded at birth. Developmental Neuropsychology, 13(2), 135–156. https://doi.org/10.1080/87565649709540674.
Molfese, D. L., Molfese, V. J., & Kelly, S. (2001). The use of brain electrophysiology techniques to study language: A basic guide for the beginning consumer of electrophysiology information. Learning Disability Quarterly, 24(3), 177. https://doi.org/10.2307/1511242.
Morris, R. D., Stuebing, K. K., Fletcher, J. M., Shaywitz, S. E., Lyon, G. R., Shankweiler, D. P., … Shaywitz, B. A. (1998). Subtypes of reading disability: Variability around a phonological core. Journal of Educational Psychology, 90(3), 347–373. https://doi.org/10.1037/0022-0663.90.3.347.
Myers, C., Vandermosten, M., Farris, R., Hancock, R., Gimenez, P., Black, J., … Hoeft, F. (2014). White matter morphometric changes uniquely predict children’s reading acquisition. Psychological Science, 25(10), 1870–1883. https://doi.org/10.1177/0956797614544511.
National Reading Panel (US), National Institute of Child Health, & Human Development (US). (2000). Report of the national reading panel: Teaching children to read: An evidence-based assessment of the scientific research literature on reading and its implications for reading instruction: Reports of the subgroups. National Institute of Child Health and Human Development, National Institutes of Health.
Neville, H. J., Coffey, S. A., Holcomb, P. J., & Tallal, P. (1993). The neurobiology of sensory and language processing in language-impaired children. Journal of Cognitive Neuroscience, 5(2), 235–253. https://doi.org/10.1162/jocn.1993.5.2.235.
Noble, K. G., McCandliss, B. D., & Farah, M. J. (2007). Socioeconomic gradients predict individual differences in neurocognitive abilities. Developmental Science, 10(4), 464–480. https://doi.org/10.1111/j.1467-7687.2007.00600.x.
Odegard, T. N., Ring, J., Smith, S., Biggan, J., & Black, J. (2008). Differentiating the neural response to intervention in children with developmental dyslexia. Annals of dyslexia, 58(1), 1.
Ozernov-Palchik, O., & Gaab, N. (2016). Tackling the “dyslexia paradox”: Reading brain and behavior for early markers of developmental dyslexia. Wiley Interdisciplinary Reviews: Cognitive Science, 7(2), 156–176. https://doi.org/10.1002/wcs.1383.
Paracchini, S., Thomas, A., Castro, S., Lai, C., Paramasivam, M., Wang, Y., … & Francks, C. (2006). The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration. Human Molecular Genetics, 15(10), 1659–1666.
Paulesu, E. (2001). Dyslexia: Cultural diversity and biological unity. Science, 291(5511), 2165–2167. https://doi.org/10.1126/science.1057179.
Paulesu, E., Danelli, L., & Berlingeri, M. (2014). Reading the dyslexic brain: multiple dysfunctional routes revealed by a new meta-analysis of PET and fMRI activation studies. Frontiers in Human Neuroscience, 8(November), 830. https://doi.org/10.3389/fnhum.2014.00830.
Paulesu, E., Frith, U., Snowling, M., Gallagher, A., Morton, J., Frackowiak, R. S. J., et al. (1996). Is developmental dyslexia a disconnection syndrome? Evidence from PET scanning. Brain, 119(1), 143–157. https://doi.org/10.1093/brain/119.1.143.
Pennington, B. F. (2006). From single to multiple deficit models of developmental disorders. Cognition, 101(2), 385–413.
Peterson, R., & Pennington, B. (2015). Developmental dyslexia. Annual Review of Clinical Psychology, 11, 283–307. https://doi.org/10.1146/annurev-clinpsy-032814-112842.
Phillips, B. M., & Lonigan, C. J. (2005). Social correlates of emergent literacy. In M. J. Snowling & C. Hulme (Eds.), The science of reading: A handbook (pp. 173–187). Oxford, UK: Blackwell Publishing Ltd. https://doi.org/10.1002/9780470757642.ch10.
Platt, M. P., Adler, W. T., Mehlhorn, A. J., Johnson, G. C., Wright, K. A., Choi, R. T., … Rosen, G. D. (2013). Embryonic disruption of the candidate dyslexia susceptibility gene homolog Kiaa0319-like results in neuronal migration disorders. Neuroscience, 248, 585–593. https://doi.org/10.1016/j.neuroscience.2013.06.056.
Plomin, R., Haworth, C. M. A., Meaburn, E. L., Price, T. S., & Davis, O. S. P. (2013). Common DNA markers can account for more than half of the genetic influence on cognitive abilities. Psychological Science, 24(4), 562–568. https://doi.org/10.1177/0956797612457952.
Powers, S. J., Wang, Y., Beach, S. D., Sideridis, G. D., & Gaab, N. (2016). Examining the relationship between home literacy environment and neural correlates of phonological processing in beginning readers with and without a familial risk for dyslexia: An fMRI study. Annals of Dyslexia, 66(3), 337–360.
Ramus, F., Rosen, S., Dakin, S. C., Day, B. L., Castellote, J. M., White, S., et al. (2003). Theories of developmental dyslexia: Insights from a multiple case study of dyslexic adults. Brain, 126(4), 841–865. https://doi.org/10.1093/brain/awg076.
Ramus, F., & Szenkovits, G. (2008) What phonological deficit? The Quarterly Journal of Experimental Psychology, 61(1),129–141. https://doi.org/10.1080/17470210701508822
Raschle, N. M., Chang, M., & Gaab, N. (2011). Structural brain alterations associated with dyslexia predate reading onset. NeuroImage, 57(3), 742–749. https://doi.org/10.1016/j.neuroimage.2010.09.055.
Raschle, N. M., Stering, P. L., Meissner, S. N., & Gaab, N. (2014). Altered neuronal response during rapid auditory processing and its relation to phonological processing in prereading children at familial risk for dyslexia. Cerebral Cortex, 24(9), 2489–2501. https://doi.org/10.1093/cercor/bht104.
Reardon, S. F., Robinson-Cimpian, J. P., & Weathers, E. S. (2014). Patterns and trends in racial/ethnic and socioeconomic academic achievement gaps. In H. A. Ladd & M. E. Goertz (Eds.), Handbook of research in education finance and policy. Mahwah, NJ: Lawrence Erlbaum.
Richlan, F., Kronbichler, M., & Wimmer, H. (2009). Functional abnormalities in the dyslexic brain: A quantitative meta-analysis of neuroimaging studies. Human Brain Mapping, 30(10), 3299–3308.
Richlan, F., Kronbichler, M., & Wimmer, H. (2013). Structural abnormalities in the dyslexic brain: A meta-analysis of voxel-based morphometry studies. Human Brain Mapping, 34(11), 3055–3065. https://doi.org/10.1002/hbm.22127.
Rimrodt, S. L., Peterson, D. J., Denckla, M. B., Kaufmann, W. E., & Cutting, L. E. (2010). White matter microstructural differences linked to left perisylvian language network in children with dyslexia. Cortex, 46(6), 739–749. https://doi.org/10.1016/j.cortex.2009.07.008.
Rumsey, J. M., Andreason, P., Zametkin, A. J., Aquino, T., King, A. C., Hamburger, S. D., … Cohen, R. M. (1992). Failure to activate the left temporoparietal cortex in dyslexia. An oxygen 15 positron emission tomographic study. Archives of Neurology, 49(5), 527–34.
Rumsey, J. M., Horwitz, B., Donohue, B. C., Nace, K., Maisog, J. M., & Andreason, P. (1997a). Phonological and orthographic components of word recognition. A PET-rCBF study. Brain, 120(5), 739–759. https://doi.org/10.1093/brain/120.5.739.
Rumsey, J. M., Nace, K., Donohue, B., Wise, D., Maisog, J. M., & Andreason, P. (1997b). A positron emission tomographic study of impaired word recognition and phonological processing in dyslexic men. Archives of Neurology, 54(5), 562–573.
Rutter, M., & Yule, W. (1975). The concept of specific reading retardation. Journal of Child Psychology and Psychiatry, 16(3), 181–197.
Salmelin, R., Kiesilä, P., Uutela, K., Service, E., & Salonen, O. (1996). Impaired visual word processing in dyslexia revealed with magnetoencephalography. Annals of Neurology, 40(2), 157–162. https://doi.org/10.1002/ana.410400206.
Saygin, Z. M., Osher, D. E., Norton, E. S., Youssoufian, D. A., Beach, S., Feather, J., Gaab, N., Gabrieli, J., K. N. (2016). Connectivity precedes function in the development of the visual word form area. Nature Neuroscience, 19(9). https://doi.org/10.1038/nn.4354.
Saygin, Z. M., Norton, E. S., Osher, D. E., Beach, S. D., Cyr, A. B., Ozernov-Palchik, O., … Gabrieli, J. D. E. (2013). Tracking the roots of reading ability: White matter volume and integrity correlate with phonological awareness in prereading and early-reading kindergarten children. The Journal of Neuroscience, 33(33), 13251–13258. https://doi.org/10.1523/jneurosci.4383-12.2013.
Schultz, J. J. (2008). Is dyslexia hereditary? family education network. https://www.school.familyeducation.com/learningdisabilities/ genetics/42788.html. Retrieved from Aug 25, 2008.
Schulz, E., Maurer, U., van der Mark, S., Bucher, K., Brem, S., Martin, E., et al. (2008). Impaired semantic processing during sentence reading in children with dyslexia: Combined fMRI and ERP evidence. NeuroImage, 41(1), 153–168. https://doi.org/10.1016/j.neuroimage.2008.02.012.
Shaywitz, B. E., Shaywitz, S. E., Blachman, B. A., Pugh, K. R., Fulbright, R. K., Skudlarski, P., Mencl, W. E., Constable, R. T., Holahan, J. M, Marchione, K. E. Fletcher, J. M., Lyon, G., R., & Gore, J. C. (2004). Development of left occipitotemporal systems for skilled reading in children after a phonologically-based intervention. Biological Psychiatry, 55, 926–933.
Shaywitz, B. A., Shaywitz, S. E., Pugh, K. R., Mencl, W. E., Fulbright, R. K., Skudlarski, P., … Gore, J. C. (2002). Disruption of posterior brain systems for reading in children with developmental dyslexia. Biological Psychiatry, 52(2), 101–110. https://doi.org/10.1016/s0006-3223(02)01365-3.
Shaywitz, S. E. (1996). Dyslexia. Scientific American, 98–104.
Shaywitz, S. E., Escobar, M. D., Shaywitz, B. A., Fletcher, J. M., & Makuch, R. (1992). Evidence that dyslexia may represent the lower tail of a normal distribution of reading ability. New England Journal of Medicine, 326, 145–150.
Shaywitz, S. E., Mody, M., & Shaywitz, B. A. (2006). Neural mechanisms in dyslexia. Current Directions in Psychological Science, 15(6), 278–281.
Shaywitz, S. E., & Shaywitz, B. A. (2008). Paying attention to reading: The neurobiology of reading and dyslexia. Development and Psychopathology, 20(4), 1329–1349. https://doi.org/10.1017/S0954579408000631.
Shaywitz, S. E., Shaywitz, B. A., Pugh, K. R., Fulbright, R. K., Constable, R. T., Mencl, W. E., … Gore, J. C. (1998). Functional disruption in the organization of the brain for reading in dyslexia. Proceedings of the National Academy of Sciences, 95(5), 2636–2641. https://doi.org/10.1073/pnas.95.5.2636.
Silani, G., Frith, U., Demonet, J. F., Fazio, F., Perani, D., Price, C., … Paulesu, E. (2005). Brain abnormalities underlying altered activation in dyslexia: A voxel based morphometry study. Brain, 128(10), 2453–2461. https://doi.org/10.1093/brain/awh579.
Simos, P. G., Fletcher, J. M., Bergman, E., Breier, J. I., Foorman, B. R., Castillo, E. M., … & Papanicolaou, A. C. (2002). Dyslexia-specific brain activation profile becomes normal following successful remedial training. Neurology, 58(8), 1203–1213.
Simos, P. G., Fletcher, J. M., Sarkari, S., Billingsley-Marshall, R., Denton, C. A., & Papanicolaou, A. C. (2007). Intensive instruction affects brain magnetic activity associated with oral word reading in children with persistent reading disabilities. Journal of Learning Disabilities, 40(1), 37–48.
Simos, P. G., Sarkari, S., Castillo, E. M., Billingsley-Marshall, R. L., Pataraia, E., Clear, T., et al. (2005). Reproducibility of measures of neurophysiological activity in Wernicke’s area: A magnetic source imaging study. Clinical Neurophysiology, 116(10), 2381–2391. https://doi.org/10.1016/j.clinph.2005.06.019.
Siok, W. T., Niu, Z., Jin, Z., Perfetti, C. A., & Tan, L. H. (2008). A structural-functional basis for dyslexia in the cortex of Chinese readers. Proceedings of the National Academy of Sciences, 105(14), 5561–5566. https://doi.org/10.1073/pnas.0801750105.
Skottun, B. C. (2005). Magnocellular reading and dyslexia. Vision Research, 45(1), 133–134. https://doi.org/10.1016/j.visres.2003.09.039.
Skyttner, L. (2006). General systems theory: Problems, perspective, practice. Singapore: World Scientific Publishing. https://doi.org/10.1142/5871.
Smythe, I., & Everatt, J. (2000). Dyslexia diagnosis in different languages. In L. Peer & G. Reid (Eds.), Multilingualism, literacy and dyslexia. London: David Fulton.
Snowling, M. J., & Melby-Lervåg, M. (2016). Oral language deficits in familial dyslexia: A meta-analysis and review. Psychological Bulletin, 142(5), 498–545.
Specht, K., Hugdahl, K., Ofte, S., Nygård, M., Bjørnerud, A., Plante, E., et al. (2009). Brain activation on pre-reading tasks reveals at-risk status for dyslexia in 6-year-old children. Scandinavian Journal of Psychology, 50(1), 79–91. https://doi.org/10.1111/j.1467-9450.2008.00688.x.
Stanovich, K. E. (1986). Matthew effects in reading: Some consequences of individual differences in the acquisition of literacy. Reading Research Quarterly, 21(4), 360–407. https://doi.org/10.1598/RRQ.21.4.1.
Stanovich, K. E., & Siegel, L. S. (1994). Phenotypic performance profile of children with reading disabilities: A regression-based test of the phonological-core variable-difference model. Journal of Educational Psychology, 86(1), 24.
Stein, J. (2001). The magnocellular theory of developmental dyslexia. Dyslexia, 7(1), 12–36. https://doi.org/10.1002/dys.186.
Stein, J. (2014). Dyslexia: The role of vision and visual attention. Current Developmental Disorders Reports, 1(4), 267–280. https://doi.org/10.1007/s40474-014-0030-6.
Szalkowski, C. E., Fiondella, C. G., Galaburda, A. M., Rosen, G. D., LoTurco, J. J., & Fitch, R. H. (2012). Neocortical disruption and behavioral impairments in rats following in utero RNAi of candidate dyslexia risk gene Kiaa0319. International Journal of Developmental Neuroscience, 30(4), 293–302. https://doi.org/10.1016/j.ijdevneu.2012.01.009.
Tallal, P. (1980). Auditory temporal perception, phonics, and reading disabilities in children. Brain and Language, 9(2), 182–198. https://doi.org/10.1016/0093-934X(80)90139-X.
Tallal, P., & Gaab, N. (2006). Dynamic auditory processing, musical experience and language development. Trends in Neuroscience, 29(7), 382–390. https://doi.org/10.1016/j.tins.2006.06.003.
Tallal, P., Stark, R., & Mellits, E. (1985). Identification of language-impaired children on the basis of rapid perception and production skills. Brain and Language, 25(2), 314–322.
Taylor, J., & Schatschneider, C. (2010). Genetic influence on literacy constructs in kindergarten and first grade: Evidence from a diverse twin sample. Behavior Genetics, 40(5), 591–602. https://doi.org/10.1007/s10519-010-9368-7.
Temple, E. (2002). Brain mechanisms in normal and dyslexic readers. Current Opinion in Neurobiology, 12(2), 178–183. https://doi.org/10.1016/S0959-4388(02),00303-3.
Temple, E., Poldrack, R. A., Protopapas, A., Nagarajan, S., Salz, T., Tallal, P., … Gabrieli, J. D. E. (2000). Disruption of the neural response to rapid acoustic stimuli in dyslexia: Evidence from functional MRI. Proceedings of the National Academy of Sciences, 97(25), 13907–13912. https://doi.org/10.1073/pnas.240461697.
Terras, M. M., Thompson, L. C., & Minnis, H. (2009). Dyslexia and psycho-social functioning: An exploratory study of the role of self-esteem and understanding. Dyslexia, 15(4), 304–327.
Thesen, T., McDonald, C. R., Carlson, C., Doyle, W., Cash, S., Sherfey, J., … Halgren, E. (2012). Sequential then interactive processing of letters and words in the left fusiform gyrus. Nature Communications, 3, 1284. https://doi.org/10.1038/ncomms2220.
Torgesen, J. K. (2000). Individual differences in response to early interventions in reading: The lingering problem of treatment resisters. Learning Disabilities Research & Practice, 15, 55–64.
Torgesen, J., Myers, D., Schirm, A., Stuart, E., Vartivarian, S., Mansfield, W., … & Haan, C. (2006). National assessment of title I: Interim report. Volume II: Closing the reading gap: First year findings from a randomized trial of four reading interventions for striving readers. National Center for Education Evaluation and Regional Assistance.
Turkheimer, E., Haley, A., Waldron, M., D’Onofrio, B., & Gottesman, I. I. (2003). Socioeconomic status modified heritability of IQ in young children. Psychological Science, 14(6), 623–628. https://doi.org/10.1046/j.0956-7976.2003.psci_1475.x.
Valås, H. (1999). Students with learning disabilities and low-achieving students: Peer acceptance, loneliness, self-esteem, and depression. Social Psychology of Education, 3(3), 173–192. https://doi.org/10.1023/A:1009626828789.
Vandermosten, M., Boets, B., Wouters, J., & Ghesquière, P. (2012). A qualitative and quantitative review of diffusion tensor imaging studies in reading and dyslexia. Neuroscience and Biobehavioral Reviews, 36(6), 1532–1552. https://doi.org/10.1016/j.neubiorev.2012.04.002.
Vandermosten, M., Vanderauwera, J., Theys, C., De Vos, A., Vanvooren, S., Sunaert, S., … Ghesquière, P. (2015). A DTI tractography study in pre-readers at risk for dyslexia. Developmental Cognitive Neuroscience, 14, 8–15. https://doi.org/10.1016/j.dcn.2015.05.006.
Vellutino, F. R., Fletcher, J. M., Snowling, M. J., & Scanlon, D. M. (2004). Specific reading disability (dyslexia): What have we learned in the past four decades? Journal of Child Psychology and Psychiatry, 45(1), 2–40.
Vellutino, F. R., Scanlon, D. M., Sipay, E. R., Small, S. G., Pratt, A., Chen, R., et al. (1996). Cognitive profiles of difficult-to-remediate and readily remediated poor readers: Early intervention as a vehicle for distinguishing between cognitive and experiential deficits as basic causes of specific reading disability. Journal of Educational Psychology, 88, 601–638.
Wada, J. A., Clarke, R., & Hamm, A. (1975). Cerebral hemispheric asymmetry in humans. Cortical speech zones in 100 adults and 100 infant brains. Archives of Neurology, 32(4), 239–246.
Willcutt, E. G., & Pennington, B. F. (2000). Comorbidity of reading disability and attention-deficit/hyperactivity disorder: Differences by gender and subtype. Journal of Learning Disabilities, 33(2), 179–191.
Willcutt, E. G., Pennington, B. F., Duncan, L., Smith, S. D., Keenan, J. M., Wadsworth, S., … & Olson, R. K. (2010). Understanding the complex etiologies of developmental disorders: behavioral and molecular genetic approaches. Journal of Developmental and Behavioral Pediatrics: JDBP, 31(7), 533.
Wimmer, H., & Goswami, U. (1994). The influence of orthographic consistency on reading development: Word recognition in English and German children. Cognition, 51(1), 91–103.
Ziegler, J. C., & Goswami, U. (2005). Reading acquisition, developmental dyslexia, and skilled reading across languages: A psycholinguistic grain size theory. Psychological Bulletin, 131(1), 3.
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Sand, L.A., Bolger, D.J. (2019). The Neurobiological Strands of Developmental Dyslexia: What We Know and What We Don’t Know. In: Kilpatrick, D., Joshi, R., Wagner, R. (eds) Reading Development and Difficulties. Springer, Cham. https://doi.org/10.1007/978-3-030-26550-2_10
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