Abstract
-
The EULAR criteria suggests a diagnosis of Henoch Schonlein purpura (HSP) to be made based on palpable purpura with lower limb predominance and at least one of the symptoms of abdominal pain, arthritis or arthralgia or signs of renal involvement or evidence of vasculitis in histopathology
-
The prognosis is excellent for most children with HSP
-
Approximately 20% of children with HSP develop renal involvement which could bear significant mortality and morbidity
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ozen S, Pistorio A, Iusan SM, et al. Paediatric Rheumatology International Trials Organisation (PRINTO). EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: final classification criteria. Ann Rheum Dis. 2010;69:798–806.
Mills JA, Michel BA, Bloch DA, et al. The American College of Rheumatology 1990 criteria for the classification of Henoch-Schonlein purpura. Arthritis Rheum. 1990;33:1114–21.
Altug UEC, Sayin DB, Ensari A. MEFV gene mutations in Henoch-Schönlein purpura. Int J Rheum Dis. 2013;16(3):347–51.
King B, Goolhoed G. Adverse skin and joint reactions associated with oral antibiotics in children: the role of cefaclor in serum sickness-like reactions. J Paediatr Child Health. 2003;39:677–81.
Michel B, Hunder G, Bloch D, Calabrese L. Hypersensitivity vasculitis and Henoch-Schönlein purpura: a comparison between the 2 disorders. J Rheumatol. 1992;19(5):721–8.
Ozen S, Ben-Chetrit E, Bakkaloglu A, et al. Semin Arthritis Rheum. 2001;30:281–7. https://doi.org/10.1053/sarh.2001.19958.
Eleftheriou D, Dillon MJ, Tullus K, Marks SD, Pilkington CA, Roebuck DJ, Klein NJ, Brogan PA. Systemic polyarteritis nodosa in the young: a single-center experience over thirty-two years. Arthritis Rheum. 2013;65(9):2476–85.
Trachtman H. HUS and TTP in children. Pediatr Clin North Am. 2013;60:1513–26.
Tarr P, Gordon C, Chandler W. Shiga-toxin-producing Escherichia coli and hemolytic uremic syndrome. Lancet (London, England). 2005;365:1073–86.
M. P. Henoch–Schönlein purpura nephritis. Pediatr Nephrol (Berlin Germany). 2015;30:245–52.
Ronkainen J, Ala-Houhala M, Huttenen M, et al. Outcome of Henoch-Schonlein nephritis with nephrotic-range proteinuria. Clin Nephrol. 2003;60:80–4.
Pacheva IH, Ivanov IS, Stefanova K, Chepisheva E, Chochkova L, Grozeva D, Stoyanova A, Milenkov S, Stefanova P, Petrova A. Central nervous system involvement in Henoch-Schonlein Purpura in children and adolescents. Case Rep Pediatr. 2017;2017:6.
Chartapisak W, Opastiraku S, Willis NS. Prevention and treatment of renal disease in Henoch-Schonlein purpura: a systematic review. Arch Dis Child. 2009;94:132–7.
Inoue CN, Chiba Y, Morimoto T, Nishio T, Kondo Y, Adachi M, Matsutani S. Tonsillectomy in the treatment of pediatric Henoch-Schönlein nephritis. Clin Nephrol. 2007;67(5):298–305.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Petty, R., Salehzadeh, F. (2020). Knee Swelling and Rash. In: Rahmani, F., Rezaei, N. (eds) Pediatric Autoimmunity and Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-030-26280-8_7
Download citation
DOI: https://doi.org/10.1007/978-3-030-26280-8_7
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-26279-2
Online ISBN: 978-3-030-26280-8
eBook Packages: MedicineMedicine (R0)