Abstract
Sodium fluoride labeled with fluorine 18 (sodium fluoride F18 [18F-NaF]) is a bone seeking positron-emitting radiopharmaceutical tracer. 18F-NaF PET/CT provides great sensitivity and specificity in the detection of bone metastases. Uptake of 18F sodium fluoride reflects blood flow and bony remodeling. When combining with the CT component of the PET/CT, it allows better morphologic characterization of the functional findings and achieves more accurate differentiation with improved specificity.
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28 October 2020
Correction to: K. Kairemo, H. A. Macapinlac (eds.), Sodium Fluoride PET/CT in Clinical Use, Clinicians’ Guides to Radionuclide Hybrid Imaging, https://doi.org/10.1007/978-3-030-23577-2_2
References
Bastawrous S, et al. Newer PET application with an old tracer: role of 18F-NaF skeletal PET/CT in oncologic practice. RadioGraphics. 2014;34:1295–316.
Sarikaya I, et al. Normal bone and soft tissue distribution of fluorine-18 sodium fluoride and artifacts on 18F NaF PET/CT bone scan: a pictorial review. Nucl Med Commun. 2017;38:810–9.
Simpson CD, et al. FDG PET/CT: artifacts and pitfalls. Contemp Diagn Radiol. 2017;40(5):1.
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Xu, G. (2020). 18F-Fluoride Imaging: Normal Variants and Artifacts. In: Kairemo, K., Macapinlac, H.A. (eds) Sodium Fluoride PET/CT in Clinical Use. Clinicians’ Guides to Radionuclide Hybrid Imaging(). Springer, Cham. https://doi.org/10.1007/978-3-030-23577-2_2
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DOI: https://doi.org/10.1007/978-3-030-23577-2_2
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