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Psoriatic Arthritis and Infection

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Infections and the Rheumatic Diseases

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Abstract

An infectious etiology for both psoriasis and psoriatic arthritis has long been suspected. Accumulated evidence supports a role for Gram-positive bacteria and other microorganism(s) including viral agents. Streptococci and HIV are among the leading triggering agents in combination with genetic and immune-related factors. Regarding the latter, cell-mediated and humoral-mediated mechanisms play an important role. More recently, microbiota has also been shown to participate in its pathogenesis. In this chapter, we focus on its genetics, immunology, and infectious basis. Much has been learned and much more remains.

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Author information

Authors and Affiliations

  1. Department of Internal Medicine, Division of Rheumatology, University of South Florida College of Medicine, Tampa, FL, USA

    Frank Barnett Vasey

  2. LSU Health Sciences at New Orleans, Louisiana State University, New Orleans, LA, USA

    Luis R. Espinoza

Authors
  1. Frank Barnett Vasey
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  2. Luis R. Espinoza
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Editor information

Editors and Affiliations

  1. LSU Health Sciences at New Orleans, Louisiana State University, New Orleans, LA, USA

    Luis R. Espinoza

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Vasey, F.B., Espinoza, L.R. (2019). Psoriatic Arthritis and Infection. In: Espinoza, L. (eds) Infections and the Rheumatic Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-23311-2_36

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