Abstract
Silybum marianum is one of the most extensively studied medicinal herbs with well-known hepatoprotective activity. This chapter gives an overview of the various approaches used to optimize induction of cell, suspension, organ, root, and transgenic cultures from S. marianum. Additionally, examples of using these different approaches are shown and discussion for the production of silymarin from S. marianum tissue culture is also detailed. This chapter summarizes the recent research work of various in vitro culture, abiotic and biotic elicitors, and precursor feeding applied to S. marianum cultural system and their stimulating effects on the accumulation of silymarin.
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Rady, M.R. (2019). Plant Biotechnology and Milk Thistle. In: Plant Biotechnology and Medicinal Plants. Springer, Cham. https://doi.org/10.1007/978-3-030-22929-0_2
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