The History of ARDS and the Need for a Pediatric Definition

Abstract

The history of ARDS is long, complex, and very interesting. The definition has been complicated by the usage of a multitude of descriptive terms (e.g., wet lung, shock lung, Da Nang lung) that were synonymous with conditions now grouped under the modern definition of ARDS. Formally described in 1967, the definition of ARDS has evolved over the past 5 decades. In the absence of a standard definition, ARDS diagnosis is established when certain criteria are met in the framework of the prevailing ARDS definition. The American-European Consensus Conference definition (1995) and the Berlin definition (2012) have refined our ability to diagnose, study, and treat ARDS, but these adult-centric definitions were not developed for children with ARDS and had their shortcomings. To address this issue, the Pediatric Acute Lung Injury Consensus Conference (PALICC) was convened to develop, among other recommendations, a specific definition for pediatric ARDS (PARDS). This new definition establishes a common language for those caring for children with PARDS and opens the door for meaningful and sustained international collaboration and rapid scientific progress.