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Experimental Data and Clinical Studies of Laser Ablation

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Book cover Image-guided Laser Ablation

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Abstract

This chapter presents an overview of the most salient experimental data derived from studies on animal models or live animal organs that are the basis of the most relevant clinical studies performed in order to establish which were the most suitable physical parameters to kill cancer cells in a safe, selective, rapid, reproducible, predictable, relatively easy, and less expensive way than alternatives. An additional final paragraph provides information on the most used laser systems in the main and important applications examined and described in the various dedicated chapters.

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Notes

  1. 1.

    As previously explained in the first chapter and reiterated in the second chapter of this book, the term “laser ablation” (LA) is associated with several alternative acronyms in the literature, including laser-induced thermal therapy (LITT), interstitial coagulation of laser (ILC) interstitial laser therapy, interstitial laser phototherapy (ILP) and photothermal therapy, a term that has gained popularity among scientists working in the field of nanotechnology.

  2. 2.

    An MR-compatible cannulation needle (length, 20 cm; diameter, 1.3 mm) with a tetragonally beveled tip and stylet, a guide wire (length, 100 cm), a 9-F sheath with stylet and a 7-F double-tube thermostabile (up to 400 °C) protective catheter with a stylet that enables internal cooling with saline solution (0.9% NaCI).

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Author information

Authors and Affiliations

  1. Department of Diagnostic Imaging and Interventional Radiology, Regina Apostolorum Hospital, Alabano Laziale, Rome, Italy

    Claudio Maurizio Pacella

  2. Department of Ultrasound, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China

    Tian’an Jiang

Authors
  1. Claudio Maurizio Pacella
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  2. Tian’an Jiang
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Editor information

Editors and Affiliations

  1. Department of Interventional Radiology, Ospedale Regina Apostolorum, Albano Laziale, Rome, Italy

    Claudio Maurizio Pacella

  2. Department of Ultrasound, Zhejiang University, Hangzhou, China

    Tian'an Jiang

  3. Division of Interventional Radiology, European Institute of Oncology, IRCCS, Milan, Italy

    Giovanni Mauri

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Pacella, C.M., Jiang, T. (2020). Experimental Data and Clinical Studies of Laser Ablation. In: Pacella, C., Jiang, T., Mauri, G. (eds) Image-guided Laser Ablation. Springer, Cham. https://doi.org/10.1007/978-3-030-21748-8_3

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  • DOI: https://doi.org/10.1007/978-3-030-21748-8_3

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