Abstract
Late diagnosis in patients with X-linked agammaglobulinemia (XLA) is associated with irreversible pulmonary complications such as bronchiectasis
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Simple screening methods, such as serum protein fractions may be useful in suspecting of antibody deficiency
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Medical treatment for XLA is by lifelong immunoglobulin replacement using Intravenous immunoglobulin (IVIG) or subcutaneous immunoglobulin (SCIG)
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Use of plasma for immunoglobulin substitution is dangerous due to possibility of transmission of blood-borne infections
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It is necessary to remember the inexpediency of serological tests is suspicion of infections and using only direct methods of detecting the pathogen
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Bondarenko, A., Chernyshova, L. (2019). Brothers with Recurrent Sinopulmonary Infections and Chronic Lung Disease. In: Rezaei, N. (eds) Pediatric Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-21262-9_9
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DOI: https://doi.org/10.1007/978-3-030-21262-9_9
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