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Bone Tissue Engineering Challenges in Craniofacial Reconstructive Surgeries

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Regenerative Medicine and Plastic Surgery

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Abstract

Craniofacial deformities can be categorized into congenital, traumatic, and cancerous ones. The author presents an overview of craniofacial defects, the available therapies, tissue engineering approach, scaffolds, polymers, ceramics, cells, and growth factors. Defects in the craniofacial region have to be considered as critical to be reconstructed. Tissue engineering seems to be a much better approach than others since it does not result in donor site morbidity and does not have the problem of the lack of suitable source in terms of quality and quantity. Although a lot of work and experimental studies have been carried out in this regard, there is a broad range of studies that remain and hoped to be done for finding the best cure for the problems.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Faculty of Engineering , University of Isfahan, Isfahan, Iran

    Seyed Mohammad Zargar & Nima Jamshidi

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  1. Seyed Mohammad Zargar
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  2. Nima Jamshidi
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Correspondence to Nima Jamshidi .

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  1. Department for Plastic Surgery and Hand Surgery, Division of Experimental Plastic Surgery, Technical University of Munich, Munich, Germany

    Dominik Duscher

  2. Private Practice, Tustin, CA, USA

    Melvin A. Shiffman

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Zargar, S.M., Jamshidi, N. (2019). Bone Tissue Engineering Challenges in Craniofacial Reconstructive Surgeries. In: Duscher, D., Shiffman, M.A. (eds) Regenerative Medicine and Plastic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-19958-6_24

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