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Hemophilia

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Hemostasis and Thrombosis

Abstract

Hemophilia A and B—lack of factors VIII and IX, respectively—are the most common forms of hemophilia. This chapter reviews the pathogenesis of hemophilia, diagnosis, and treatment including the use of desmopressin and factor concentrates.

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Suggested Reading

  • Croteau SE. Evolving complexity in hemophilia management. Pediatr Clin N Am. 2018;65(3):407–25.

    Article  Google Scholar 

  • Dunn A. The long and short of it: using the new factor products. Hematology Am Soc Hematol Educ Program. 2015;2015:26–32.

    Article  Google Scholar 

  • Mahlangu J, Oldenburg J, Paz-Priel I, Negrier C, Niggli M, Mancuso ME, Schmitt C, Jiménez-Yuste V, Kempton C, Dhalluin C, Callaghan MU, Bujan W, Shima M, Adamkewicz JI, Asikanius E, Levy GG, Kruse-Jarres R. Emicizumab prophylaxis in patients who have hemophilia A without inhibitors. N Engl J Med. 2018;379(9):811–22.

    Article  CAS  Google Scholar 

  • Nogami K, Shima M. New therapies using nonfactor products for patients with hemophilia and inhibitors. Blood. 2019;133(5):399–406.

    Article  CAS  Google Scholar 

  • Srivastava A, Brewer AK, Mauser-Bunschoten EP, et al. Guidelines for the management of hemophilia. Haemophilia. 2013;19(1):e1–47.

    Article  CAS  Google Scholar 

  • Weyand AC, Pipe SW. New therapies for hemophilia. Blood. 2019;133(5):389–98.

    Article  CAS  Google Scholar 

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Correspondence to Thomas G. DeLoughery .

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DeLoughery, T.G. (2019). Hemophilia. In: DeLoughery, T. (eds) Hemostasis and Thrombosis. Springer, Cham. https://doi.org/10.1007/978-3-030-19330-0_4

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  • DOI: https://doi.org/10.1007/978-3-030-19330-0_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-19329-4

  • Online ISBN: 978-3-030-19330-0

  • eBook Packages: MedicineMedicine (R0)

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