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Pharmacogeriatrics and the Kidney

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Clinical Nephrogeriatrics

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Abstract

Older people constitute a particular group regarding pharmacotherapeutics for many reasons. They are high consumers of prescription drugs (up to 30% of all commonly prescribed medications); the age-related pharmacokinetic and pharmacodynamic changes and high rate of comorbidities put them at an increased risk of drug interactions, adverse effects, and inadequate dosing. In this chapter we are going to describe how physiology changes secondary to aging can predispose elderly people to suffer from pharmacological adverse effects and their impact over the pharmacology of drugs may help to optimize drug use and to avoid complications in this age group.

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Author information

Authors and Affiliations

  1. Clinical Pharmacology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    Paula Scibona & Waldo H. Belloso

Authors
  1. Paula Scibona
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  2. Waldo H. Belloso
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Editors and Affiliations

  1. Nephrology Division, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    Carlos Guido Musso

  2. Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    José Ricardo Jauregui

  3. Departamento de Medicina, Salamanca, Spain

    Juan Florencio Macías-Núñez

  4. University of Medicine “Grigore T. Popa” and University Hospital “C. I. Parhon”, Iasi, Romania

    Adrian Covic

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Scibona, P., Belloso, W.H. (2019). Pharmacogeriatrics and the Kidney. In: Musso, C., Jauregui, J., Macías-Núñez, J., Covic, A. (eds) Clinical Nephrogeriatrics. Springer, Cham. https://doi.org/10.1007/978-3-030-18711-8_16

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  • DOI: https://doi.org/10.1007/978-3-030-18711-8_16

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-030-18711-8

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