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The Diagnosis of Bovine Tuberculosis

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Book cover Tuberculosis in Animals: An African Perspective

Abstract

To successfully deal with any specific disease, it is critical to make a correct diagnosis and then to institute the necessary measures to control, and, if possible, to eradicate it. For some diseases this is not a complicated matter, but for Mycobacterium bovis that infects a wide range of mammals, including humans, there is not a single test or procedure by which to reliably confirm the diagnosis in all infected and diseased animals, mostly because of the lack of sensitivity and specificity of all the currently available tests. The various species that can be infected react immunologically different to the infection, respond differently to the various immune-mediated diagnostic tests, show a marked variation in the macro- and microscopical appearance of the lesions caused by the infection and change their appearance as the disease progresses. It is critical to understand that the diagnostic criteria for the different tests in a specific species cannot be used in species in which they have not been validated, and that extrapolation between species cannot be done as the test results cannot then be interpreted correctly. This chapter provides an overview of the currently available diagnostic tests, their deficiencies, and the way in which they can be applied in resource-poor countries to aid efforts to control bovine tuberculosis.

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Authors and Affiliations

  1. Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa

    Nicolaas P. J. Kriek

  2. Department of Biological Sciences, Minnesota State University, Mankato, Mankato, MN, USA

    Demelash B. Areda

  3. Department of Pathobiology, College of Veterinary Medicine, Tuskegee University, Tuskegee, AL, USA

    Asseged B. Dibaba

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  1. Nicolaas P. J. Kriek
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  2. Demelash B. Areda
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  3. Asseged B. Dibaba
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  1. Department of Pathobiology, College of Veterinary Medicince, Tuskegee University, Tuskegee, AL, USA

    Asseged B. Dibaba

  2. Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa

    Nicolaas P. J. Kriek

  3. Department of Veterinary Microbiology and Preventive Medicine, Iowa State University College of Veterinary Medicine, Ames, IA, USA

    Charles O. Thoen

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Kriek, N.P.J., Areda, D.B., Dibaba, A.B. (2019). The Diagnosis of Bovine Tuberculosis. In: Dibaba, A., Kriek, N., Thoen, C. (eds) Tuberculosis in Animals: An African Perspective. Springer, Cham. https://doi.org/10.1007/978-3-030-18690-6_9

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