Practical Points
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Food-protein induced enterocolitis syndrome (FPIES) is a disorder most commonly seen in infants between 1-3 weeks of age, with gross or microscopic hematochezia
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The reaction is most common in exclusively breast fed infants as a result of cow’s milk or soy protein in mothers diet
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Elimination of the responsible allergen leads to resolution of hematochezia within 72 h
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References
Cherian S, Varshney P. Food protein-induced enterocolitis syndrome (FPIES): review of recent guidelines. Curr Allergy Asthma Rep. 2018;18(4):28.
Leonard SA, Pecora V, Fiocchi AG, Nowak-Wegrzyn A. Food protein-induced enterocolitis syndrome: a review of the new guidelines. World Allergy Organ J. 2018;11(1):4.
Greer FR, Sicherer SH, Burks AW, American Academy of Pediatrics Committee on Nutrition; American Academy of Pediatrics Section on Allergy and Immunology. Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas. Pediatrics. 2008;121(1):183–91.
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Sharafian, S. (2019). Bloody Streaks in Stool. In: Rezaei, N. (eds) Pediatric Allergy. Springer, Cham. https://doi.org/10.1007/978-3-030-18282-3_13
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DOI: https://doi.org/10.1007/978-3-030-18282-3_13
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