Abstract
Antidepressants and anticonvulsants are widely used to treat a wide variety of pain disorders.
These medications have significant utility not only in the treatment of neuropathic pain but also in the management of nociceptive and mixed pain types, as well. Caution must be exercised when prescribing these compounds, as many have significant side effects and drug interactions, to which the elderly are particularly susceptible.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Change history
27 March 2021
The book was inadvertently published with incorrect authorships in Chapters 13, 14 and 47. It has been updated along with corresponding affiliation information as follows: Chapter 13:
References
DeBattista C. Antidepressant agents. In: Katzung BG, Trevor AJ, editors. Basic & clinical pharmacology. 13th ed. New York: McGraw-Hill; 2015.
Verdu B. Antidepressants for the treatment of chronic pain. Drugs. 2008;68(18):2611–32.
Kasper S, Pail G. Milnacipran: a unique antidepressant? Neuropsychiatr Dis Treat. 2010;6(Suppl I):23–31. https://doi.org/10.2147/NDT.S11777.
Shelton R. Serotonin norepinephrine reuptake inhibitors: similarities and differences. Prim Psychiatry. 2009;15:5(Suppl 4):25–35.
Roe M, et al. Pharmacology in the management of chronic pain. Anaesth Intensive Care Med. 2016;17(11):548–51.
Derry S, Gill D, Phillips T, Moore RA. Milnacipran for neuropathic pain and fibromyalgia in adults. Cochrane Database Syst Rev. 2012;(3):Art. No.: CD008244. https://doi.org/10.1002/14651858.CD008244.pub2.
Celikyurt IK, Mutlu O, Ulak G. Serotonin Noradrenaline Reuptake Inhibitors (SNRIs), Effects of antidepressants, Dr. Ru-Band Lu (Ed.), InTech, 2012. https://doi.org/10.5772/37999.
Selke KJ, Dhar G, Cohn JM. Takotsubo cardiomyopathy associated with titration of duloxetine. Tex Heart Inst J. 2011;38(5):573–6.
Park HJ, Moon DE. Pharmacologic management of chronic pain. Korean J Pain. 2010;23(2):99–108. https://doi.org/10.3344/kjp.2010.23.2.99.
Aronoff GM, Gallagher RM, Patel JG. Pharmacological management of chronic pain: a review. In: Tollison CD, et al., editors. Practical pain management. 3rd ed. Philadelphia: Lippincott Williams and Wilkins; 2002.
Perruca E. The clinical pharmacokinetics of the new antiepileptic drugs. Epilepsia. 1999;40(Suppl):S7–S13.
Sidhu HS, Sadhotra A. Current status of the new antiepileptic drugs in chronic pain. Front Pharmacol. 2016;7:276. https://doi.org/10.3389/fphar.2016.00276.
Ryder S-A, Stannard CF. Treatment of chronic pain: antidepressant, antiepileptic and antiarrhythmic drugs. Contin Educ Anaesth Crit Care Pain. 2005;5(1):18–21.
Rose MA, Kam PCA. Gabapentin: pharmacology and its use in pain management. Anaesthesia. 2002;57:451–62.
Dinakar P. Principles in pain management. In: Daroff RB, Jankovic J, et al., editors. Bradley’s neurology in clinical practice. 7th ed. Philadelphia: Elsevier Health Sciences; 2015.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Okafor, C., Aquino, M. (2019). Antidepressants and Anticonvulsants. In: Khelemsky, Y., Malhotra, A., Gritsenko, K. (eds) Academic Pain Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-18005-8_14
Download citation
DOI: https://doi.org/10.1007/978-3-030-18005-8_14
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-18004-1
Online ISBN: 978-3-030-18005-8
eBook Packages: MedicineMedicine (R0)