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Maternal Drug Use and Infant Congenital Malformations pp 15–22Cite as

Maternal Use of Antacids or Drugs for Gastroesophageal Reflux Diagnosis (GERD) or Stomach Ulcer and Infant Congenital Malformations

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Abstract

Most previous studies indicate that the use of antacids or drugs for GERD carries no increased risk for infant congenital malformations. This has been verified in the present study with respect to antacids, H2-receptor antagonists, and proton pump inhibitors. Some questions remain concerning the use of sucralfate therapy where a weak teratogenic effect seems to exist. A specific association between use of sucralfate or alginic acid and infant esophageal atresia is suggested but has to be verified in independent studies. The absolute risk is, if existent, negligible.

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Authors and Affiliations

  1. Tornblad Institute for Comparative Embryology, Lund University, Lund, Sweden

    Bengt Källén

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  1. Bengt Källén
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Källén, B. (2019). Maternal Use of Antacids or Drugs for Gastroesophageal Reflux Diagnosis (GERD) or Stomach Ulcer and Infant Congenital Malformations. In: Maternal Drug Use and Infant Congenital Malformations. Springer, Cham. https://doi.org/10.1007/978-3-030-17898-7_2

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  • DOI: https://doi.org/10.1007/978-3-030-17898-7_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-17897-0

  • Online ISBN: 978-3-030-17898-7

  • eBook Packages: MedicineMedicine (R0)

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