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Essential Oil Research pp 211–233Cite as

Outstanding Efficacy of Essential Oils Against Oral Pathogens

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Abstract

The essential oils (EOs), 30 tested on Streptococcus sanguinis and 21 on Streptococcus salivarius, expressed satisfactory antimicrobial activity (MIC ≤ 250 μL mL−1) on clinical isolates or corresponding referent strains (ATCC 10556 and ATCC 9222). S. sanguinis was more sensitive than S. salivarius on cineole-rich lacking thymol oils, while S. salivarius was more sensitive than S. sanguinis on thymol-rich lacking cineole oils. Analysis of the MIC values within the groups (MIC-strong or MIC-good) revealed that the clinical isolates of both Streptococcus species generally show lower sensitivity to EOs than their corresponding referent strains. Analysis of data for MIC-strong EOs tested on both ATCC Streptococcus strains revealed that in the class of monoterpene hydrocarbons, one should look for the presence of myrcene, α-thujone, α-phellandrene, and o-cymene, while in the class of oxygenated monoterpenes, the desired constituents should be camphor, 1,8-cineole, carvacrol, eugenol, and linalyl acetate.

The aim of this chapter is to present EOs with the most significant in vitro activity against Streptococcus sanguinis and Streptococcus salivarius, major human oral pathogens, and to estimate which of their constituents might contribute to desired activity, as “markers compounds.”

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Acknowledgments

The authors appreciate financial support of the Ministry of Education, Science and Technological Development of Republic of Serbia (Grants № 172026 and 173032).

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Authors and Affiliations

  1. “Vinča” Institute of Nuclear Sciences, Mike Petrovića Alasa 12, University of Belgrade, Belgrade, Serbia

    Jelena Marinković

  2. Institute for Medicinal Plant Research “Dr. Josif Pančić”, Tadeuša Koščuška 1, Belgrade, Serbia

    Tatjana Marković

  3. Department for Medical Statistics and Informatics, School of Dental Medicine, Dr. Subotića 1, University of Belgrade, Belgrade, Serbia

    Biljana Miličić

  4. Institute for Biological Research “Siniša Stanković”, Bulevar Despota Stefana 142, University of Belgrade, Belgrade, Serbia

    Marina Soković & Ana Ćirić

  5. Department of Pediatric and Preventive Dentistry, School of Dental Medicine, Dr. Subotića 11, University of Belgrade, Belgrade, Serbia

    Dejan Marković

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  1. Jelena Marinković
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  2. Tatjana Marković
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  4. Marina Soković
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Correspondence to Marina Soković .

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  1. ARC Centre of Excellence in Plant Energy Biology and School of Agriculture, Food and Wine, University of Adelaide, Glen Osmond, SA, Australia, Graduate Program in Health Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Maranhão, Brazil

    Sonia Malik

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Marinković, J., Marković, T., Miličić, B., Soković, M., Ćirić, A., Marković, D. (2019). Outstanding Efficacy of Essential Oils Against Oral Pathogens. In: Malik, S. (eds) Essential Oil Research. Springer, Cham. https://doi.org/10.1007/978-3-030-16546-8_7

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