Abstract
Actual industrial enzymes have often high cost and instability. Such issues have restricted commercial application of such fragile biomolecules. Alternatively, immobilization of enzymes on suitable supports improves stability, cost-effectiveness and recyclability. Chitin and chitosan are ideal supporting material because they are biocompatible, biodegradable, plenty of reactive functional groups, non-toxic and cheap. Different derivatives of chitin support such as chitosan, chitosan film, chitosan nanoparticle, and chitosan nanocomposite has been used for enzyme immobilization. Chitosan-bound biomolecules display considerably improved biocatalytic potential as compared to native biomolecules. Chitosan immobilized enzymes have exceptionally high operational stability and reusability, and thus are suitable for industrial processing. This chapter reviews enzymes immobilized on chitin- and chitosan-based biomaterials, and applications to drug delivery and sustainable agriculture.
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Verma, M.L., Kumar, S., Das, A., Randhawa, J.S., Chamundeeswari, M. (2019). Enzyme Immobilization on Chitin and Chitosan-Based Supports for Biotechnological Applications. In: Crini, G., Lichtfouse, E. (eds) Sustainable Agriculture Reviews 35. Sustainable Agriculture Reviews, vol 35. Springer, Cham. https://doi.org/10.1007/978-3-030-16538-3_4
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