Skip to main content
  • 1356 Accesses

Abstract

This chapter gives an account of the classifications, epidemiology, pathology, clinical features, diagnosis, radiological features, and treatment including treatment of chronic forms of the disease.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Lew DP, Waldvogel FA. Organisms isolated in bacterial osteomyelitis. N Engl J Med. 1997;336:999–1007.

    Article  CAS  PubMed  Google Scholar 

  2. Blyth MJ, Kincaid R, Craigen MA, Bennet GC. The changing epidemiology of acute and subacute haematogenous osteomyelitis in children. J Bone Joint Surg (Br). 2001;83:99–102.

    Article  CAS  Google Scholar 

  3. Gillespie WJ. Epidemiology in bone and joint infection. Infect Dis Clin N Am. 1990;4:361–76.

    CAS  Google Scholar 

  4. Plotquin D, Dekel S, Katz S, Danon A. Prostaglandin release by normal and osteomyelitic human bones. Prostaglandins Leukot Essent Fat Acids. 1991;43:13–5.

    Article  CAS  Google Scholar 

  5. Ralston SH. Role of cytokines in clinical disorders of bone metabolism. In: Gowen M, editor. Cytokines and bone metabolism. Boca Raton, FL: CRC Press; 1992. p. 370–1.

    Google Scholar 

  6. Subasi M, Kapukaya A, Kesemenli C, Kaya H, Sari I. Effect of granulocytemacrophage colony-stimulating factor on treatment of acute osteomyelitis. An experimental investigation in rats. Arch Orthop Trauma Surg. 2001;121:170–3.

    Article  CAS  PubMed  Google Scholar 

  7. Mader JT, Brown GL, Guckian JC, Wells CH, Reinarz JA. A mechanism for the amelioration by hyperbaric oxygen of experimental staphylococcal osteomyelitis in rabbits. J Infect Dis. 1980;142:915–22.

    Article  CAS  PubMed  Google Scholar 

  8. Ericsson HM, Sherris JC. Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathol Microbiol Scand B: Microbiol Immunol. 1971;217(Suppl 217):1–90.

    Google Scholar 

  9. Bonakdarpour A, Gaines VD. The radiology of osteomyelitis. Orthop Clin North Am. 1983;14:21–33.

    CAS  Google Scholar 

  10. Cardinal E, Bureau NJ, Aubin B, Chhem RK. Role of ultrasound in muskuloskeletal infections. Radiol Clin N Am. 2001;39:191–201.

    Article  CAS  PubMed  Google Scholar 

  11. Morbach H, Schneider P. Comparison of magnetic resonance imaging and 99mTechnetium-labelled methylene diphosphonate bone scintigraphy in the initial assessment of chronic non-bacterial osteomyelitis of childhood and adolescents. Clin Exp Rheumatol. 2012;30(4):578–82.

    PubMed  Google Scholar 

  12. Morrey B-F, Peterson HA. Hematogenous pyogenic osteomyelitis in children. Orthop Clin North Am. 1975;6:935–51.

    CAS  PubMed  Google Scholar 

  13. Peltola H, Vahvanen V. A comparative study of osteomyelitis and purulent arthritis with special reference to aetiology and recovery. Infection. 1984;12:75–7.

    Article  CAS  PubMed  Google Scholar 

  14. Nade S. Antibiotics in the management of acute haematogenous osteomyelitis and acute septic arthritis in infancy and childhood. Aust N Z J Surg. 1978;48:78–80.

    Article  CAS  PubMed  Google Scholar 

  15. Jagdzinski NA, Kanwar R, Graham K, Bache CE. Prosprective evaluation of a shortened regimen of treatment of acute osteomyelitis and septic arthritis in children. J Pediatr Orthop. 2009;29(5):518–25.

    Google Scholar 

  16. Ramos OM. Chronic osteomylitis in children. Pediatr Infect Dis J. 2002;21:431–2.

    Article  PubMed  Google Scholar 

  17. Gledhill RB. Subacute osteomyelitis in children. Clin Orthop. 1973;96:57–69.

    Article  Google Scholar 

  18. Roberts JM, Drummond DS, Breed AL, Chesney J. Subacute hematogeneous osteomyelitis in children: a retrospective study. J Pediatr Orthop. 1982;2:249–54.

    Article  CAS  PubMed  Google Scholar 

  19. Cierny G, Mader JT, Pennick H. A clinical staging system of adult osteomyelitis. Contemp Orthop. 1985;10:17–37.

    Google Scholar 

  20. Termaat MF, Raijmakers PG, Scholten HJ, Bakker FC, Patka P, Haarman HJ. The accuracy of diagnostic imaging for the assessment of chronic osteomyelitis: a systematic review and meta-analysis. J Bone Joint Surg Am. 2005;87:2464–71.

    CAS  PubMed  Google Scholar 

  21. Kagna O, Srour S. FDG PET/CT imaging in the diagnosis of osteomyelitis in the diabetic foot. Eur J Nucl Med Mol Imaging. 2012;39(10):1545–50.

    Article  PubMed  Google Scholar 

  22. Simpson AH, Deakin M, Latham JM. Chronic osteomyelitis. The effect of the extent of surgical resection on infection-free survival. J Bone Joint Surg (Br). 2001;83:403–7.

    Article  CAS  Google Scholar 

  23. Patzakis MJ, Mazur K, Wilkins J, et al. Septopal beads and autogenous bone grafting for bone defects in patients with chronic osteomyelitis. Clin Orthop Relat Res. 1993;295:112–8.

    Google Scholar 

  24. Modi SP, Eppes SC, Klein JD. Cat-scratch disease presenting as multifocal osteomyelitis with thoracic abscess. Pediatr Infect Dis J. 2001;20:1006–7.

    Article  CAS  PubMed  Google Scholar 

  25. Gitelis S, Brebach GT. The treatment of chronic osteomyelitis with a biodegradable antibiotic-impregnated implant. J Orthop Surg. 2002;10(1):53–60.

    Article  Google Scholar 

  26. Chan YS, Ueng SW, Wang CJ, Lee SS, Chen CY, Shin CH. Antibiotic impregnated autogenic cancellous bone grafting is an effective and safe method for the management of small infected tibial defects: a comparison study. J Trauma. 2000;48:246–55.

    Article  CAS  PubMed  Google Scholar 

  27. Mooney JF, Argenta LC, Marks MW, Morykwas MJ, DeFranzo AJ. Treatment of soft tissue defects in pediatric patients using the V.A.C. system. Clin Orthop. 2000;376:26–31.

    Article  Google Scholar 

  28. Herscovici D Jr, Sanders RW, Scaduto JM, Infante A, DiPasquale T. Vacuum-assisted wound closure (VAC therapy) for the management of patients with high-energy soft tissue injuries. J Orthop Trauma. 2003;17:683–8.

    Article  PubMed  Google Scholar 

  29. Kaya M, Şimşek-Kaya G, Gürsan N, Kireççi E, Dayi E, Gündoğdu B. Local treatment of chronic osteomyelitis with surgical debridement and tigecycline impregnated calcium hydroxyapatite: an experimental study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113(3):340–7.

    Article  PubMed  Google Scholar 

  30. Cattaneo R, Catagni M, Johnson EE. The treatment of infected nonunions and segmental defects of the tibia by the methods of lizarov. Clin Orthop. 1992;280:143–52.

    Google Scholar 

  31. Morandi M, Zembo MM, Ciotti M. Infected tibial pseudarthrosis. A 2-year follow up on patients treated by the Ilizarov technique. Orthopedics. 1989;12:497–508.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Iyer, K.M. (2019). Infection. In: Iyer, K., Khan, W. (eds) General Principles of Orthopedics and Trauma. Springer, Cham. https://doi.org/10.1007/978-3-030-15089-1_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-15089-1_4

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-15088-4

  • Online ISBN: 978-3-030-15089-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics