Abstract
Vertebral compression fractures are an important cause of back pain and disability in patients with osteoporosis and spinal neoplasms. Vertebroplasty is a minimally invasive procedure that involves the percutaneous injection of cement into the fractured vertebral body. This procedure is generally offered as a treatment option for a small subset of patients with symptomatic osteoporotic or neoplastic vertebral fractures that result in significant pain and disability.
There is high-quality evidence to treat selected patients with severe pain within 6 weeks of osteoporotic vertebral fracture. There is moderate quality of evidence regarding the effectiveness of these procedures in the treatment of subacute and chronic osteoporotic and neoplastic vertebral compression fractures. Appropriate patient selection combined with careful procedural techniques results in the best patient outcomes. This chapter will outline the historical background and evidence for efficacy and safety and discuss clinical pearls to aid clinicians in optimizing patient selection and procedural outcomes from vertebroplasty.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Recommended Reading
Buchbinder R, Osborne RH, Ebeling PR, Wark JD, Mitchell P, Wriedt C, et al. A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med. 2009;361(6):557–68.
Chandra RV, Meyers PM, Hirsch JA, Abruzzo T, Eskey CJ, Hussain MS, et al. Vertebral augmentation: report of the Standards and Guidelines Committee of the Society of NeuroInterventional Surgery. J Neurointerv Surg. 2014;6:7–15.
Chew C, Craig L, Edwards R, Moss J, O’Dwyer PJ. Safety and efficacy of percutaneous vertebroplasty in malignancy: a systematic review. Clin Radiol. 2011;66:63–72.
Clark W, Bird P, Gonski P, Diamond TH, Smerdely P, McNeil HP, et al. Safety and efficacy of vertebroplasty for acute painful osteoporotic fractures (VAPOUR): a multicentre, randomised, double-blind, placebo-controlled trial. The Lancet. 2016;388(10052):1408–16.
Kallmes DF, Comstock BA, Heagerty PJ, Turner JA, Wilson DJ, Diamond TH, et al. A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med. 2009;361(6):569–79.
Klazen CAH, Lohle PNM, de Vries J, Jansen FH, Tielbeek AV, Blonk MC, et al. Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomized trial. The Lancet. 2010;376(9746):1085–92.
Tsoumakidou G, Too CW, Koch G, Caudrelier J, Cazzato RL, Garnon J, et al. CIRSE Guidelines on Percutaneous Vertebral Augmentation. Cardiovasc Intervent Radiol. 2017;40(3):331–4.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Maingard, J. et al. (2019). Vertebroplasty and Other Methods of Vertebral Augmentation. In: Deer, T., Pope, J., Lamer, T., Provenzano, D. (eds) Deer's Treatment of Pain. Springer, Cham. https://doi.org/10.1007/978-3-030-12281-2_95
Download citation
DOI: https://doi.org/10.1007/978-3-030-12281-2_95
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-12280-5
Online ISBN: 978-3-030-12281-2
eBook Packages: MedicineMedicine (R0)