Skip to main content

Is It OSA or Depression or Both?

  • Chapter
  • First Online:
Comorbid Sleep and Psychiatric Disorders

Abstract

Obstructive sleep apnea (OSA) and depression are common illnesses that frequently coexist in the same patient. Both can also be associated with several chronic, severe medical conditions including diabetes and cardiovascular disease. The symptoms of OSA and depression often overlap leading to frequent underdiagnosis of OSA patients who present to psychiatric clinics with symptoms of depression. Undiagnosed OSA in patients with depression can lead to poor outcomes and treatment failures. Clinicians need to be aware of the relationship between these two conditions since increased diagnostic accuracy can produce better outcomes for both conditions.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. American Sleep Assoc. (2018). Sleep Statistics – Research & Treatments | American Sleep Assoc. [online] Available at: https://www.sleepassociation.org/about-sleep/sleep-statistics/. Accessed 8 Apr 2018.

  2. Mosko S, Zetin M, Glen S, Garber D, DeAntonio M, Sassin J, McAnich J, Warren S. Self-reported depressive symptomatology, mood ratings, and treatment outcome in sleep disorders patients. J Clin Psychol. 1989;45(1):51–60. https://doi.org/10.1002/1097-4679(198901)45:1<51::aid-jclp2270450107>3.0.co;2-h.

    Article  CAS  Google Scholar 

  3. Khawaja IS, Kazaglis L, Hashmi A, Khurshid KA, Eiken C, Hurwitz TD. Obstructive sleep apnea and depression: a review. Psychiatr Ann. 2016;46(3):187–91. https://doi.org/10.3928/00485713-20160125-02.

    Article  Google Scholar 

  4. BaHammam AS, Kendzerska T, Gupta R, Ramasubramanian C, Neubauer DN, Narasimhan M, Pandi-Perumal SR, Moscovitch A. Comorbid depression in obstructive sleep apnea: an under-recognized association. Sleep Breath. 2016;20(2):447–56. https://doi.org/10.1007/s11325-015-1223-x.

    Article  PubMed  Google Scholar 

  5. Chen Y, Keller J, Kang J, Hsieh H Lin H. Obstructive sleep apnea and the subsequent risk of depressive disorder: a population-based follow-up study. J Clin Sleep Med. 2013. https://doi.org/10.5664/jcsm.2652.

  6. Kasasbeh E, Chi D, Krishnaswamy G. Inflammatory aspects of sleep apnea and their cardiovascular consequences. South Med J. 2006;99(1):58–67. https://doi.org/10.1097/01.smj.0000197705.99639.50.

    Article  CAS  PubMed  Google Scholar 

  7. Irwin M, Miller A. Depressive disorders and immunity: 20 years of progress and discovery. Brain Behav Immun. 2007;21(4):374–83. https://doi.org/10.1016/j.bbi.2007.01.010.

    Article  CAS  PubMed  Google Scholar 

  8. Somers VK, White DP, Amin R, Abrahan WT, Costa F, Culebras A, Daniels S, Floras JS, Hunt CE, Olson LJ, Pickering TG, Russell R, Woo M, Young T. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. J Am Coll Cardiol. 2008;52:686–717. https://doi.org/10.1161/circulationaha.107.189420.

    Article  PubMed  Google Scholar 

  9. Moulton CD, Pickup JC, Ismail K. The link between depression and diabetes: the search for shared mechanisms. Lancet Diabetes Endocrinol. 2015;3(6):461–71. https://doi.org/10.1016/s2213-8587(15)00134-5.

    Article  PubMed  Google Scholar 

  10. Tantrakul V, Numthavaj P, Guilleminault C, McEvoy M, Panburana P, Khaing W, Attia J, Thakkinstian A. Performance of screening questionnaires for obstructive sleep apnea during pregnancy: a systematic review and meta-analysis. Sleep Med Rev. 2017;36:96–106. https://doi.org/10.1016/j.smrv.2016.11.003.

    Article  PubMed  Google Scholar 

  11. Barnes M, Houston D, Worsnop CJ, Neill AM, Mykytyn IJ, Kay A, et al. A randomized controlled trial of continuous positive airway pressure in mild obstructive sleep apnea. Am J Respir Crit Care Med. 2002;165(6):773–80. https://doi.org/10.1164/ajrccm.165.6.2003166.

    Article  PubMed  Google Scholar 

  12. Rosenberg RS. Depression in the sleep center: are we treating the whole patient? Sleep Med. 2003;4(4):269. https://doi.org/10.1016/s1389-9457(03)00056-x.

    Article  PubMed  Google Scholar 

  13. Ejaz SM, Khawaja IS, Bhatia S, Hurwitz TD. Obstructive sleep apnea and depression: a review. Innov Clin Neurosci. 2011;8(8):17.

    PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Wolfgang Schmidt-Nowara .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Hashmi, A.M., Khawaja, I.S., Schmidt-Nowara, W. (2019). Is It OSA or Depression or Both?. In: Khawaja, I., Hurwitz, T. (eds) Comorbid Sleep and Psychiatric Disorders. Springer, Cham. https://doi.org/10.1007/978-3-030-11772-6_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-11772-6_1

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-11771-9

  • Online ISBN: 978-3-030-11772-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics