Abstract
The skeletal system is developing throughout fetal life and continues to develop well into postnatal life. The changes in the skeleton in embryonic and fetal life are dramatic, and the study of the normal histological changes in bone development can be important for understanding abnormalities encountered in such disease states as intrauterine growth restriction, skeletal dysplasia, and metabolic disturbances. This chapter reviews the normal development of the skeletal system and the histological components of the bone throughout gestation.
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Sadler TW, Langman J. Langman’s medical embryology. 11th ed. Philadelphia: Wolters Kluwer Lippincott Williams & Wilkins; 2010.
Schoenwolf GC, Larsen WJ. Larsen’s human embryology. 4th ed. Philadelphia: Elsevier/Churchill Livingstone; 2009.
O’Rahilly R, Müller F. The skeletal system and the limbs. In: Human embryology & teratology. 3rd ed. New York: Wiley-Liss; 2001. p. 357–94.
Siebert J. Perinatal, fetal and embryonic autopsy. In: Gilbert-Barness E, editor. Potter’s pathology of the fetus, infant, and child. 2nd ed. Philadelphia: Mosby Elsevier; 2007. p. 712.
Rosenberg AE, Roth SI. Bone. In: Mills SE, editor. Histology for pathologists. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2012. p. 85–106.
Gilbert-Barness E. Osteochondrodysplasia—constitutional diseases of bone. In: Gilbert-Barness E, editor. Potter’s pathology of the fetus, infant, and child. 2nd ed. Philadelphia: Mosby Elsevier; 2007. p. 1836–97.
Yang SS. The skeletal system. In: Wigglesworth JS, Singer DB, editors. Textbook of fetal and perinatal pathology. 2nd ed. Malden: Blackwell Science; 1998. p. 1039–82.
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Ernst, L.M. (2019). Bone. In: Ernst, L., Ruchelli, E., Carreon, C., Huff, D. (eds) Color Atlas of Human Fetal and Neonatal Histology. Springer, Cham. https://doi.org/10.1007/978-3-030-11425-1_32
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DOI: https://doi.org/10.1007/978-3-030-11425-1_32
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