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Phosphorescence Lifetime Imaging (PLIM): State of the Art and Perspectives

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Progress in Photon Science

Part of the book series: Springer Series in Chemical Physics ((CHEMICAL,volume 119))

Abstract

This chapter reviews the status and perspectives of phosphorescence lifetime imaging (PLIM), an advanced imaging strategy that relies on phosphorescence lifetime measuring as a function of some particular biological microenvironment parameters. PLIM should be regarded as a functional imaging technique, as opposite to various forms of “localization” techniques, because it provides not only information on distribution pattern of the probe but also determines its “status” (via lifetime reporting).

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Acknowledgements

The authors greatly appreciate financial support from the Russian Science Foundation (grant 16-43-03003) and the organizing committee of the STEPS program for the support in publication of this review.

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Authors and Affiliations

  1. Institute of Chemistry, St. Petersburg State University, Universitetskii pr., 26, Saint Petersburg, 198504, Russia

    Pavel S. Chelushkin & Sergey P. Tunik

Authors
  1. Pavel S. Chelushkin
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  2. Sergey P. Tunik
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Correspondence to Sergey P. Tunik .

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Editors and Affiliations

  1. Department of Chemistry, The University of Tokyo, Tokyo, Japan

    Kaoru Yamanouchi

  2. Institute of Chemistry, Saint Petersburg State University, Saint Petersburg, Russia

    Sergey Tunik

  3. Physics Faculty, Lomonosov Moscow State University, Moscow, Russia

    Vladimir Makarov

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Chelushkin, P.S., Tunik, S.P. (2019). Phosphorescence Lifetime Imaging (PLIM): State of the Art and Perspectives. In: Yamanouchi, K., Tunik, S., Makarov, V. (eds) Progress in Photon Science. Springer Series in Chemical Physics, vol 119. Springer, Cham. https://doi.org/10.1007/978-3-030-05974-3_6

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