Abstract
The world is impacting with a drastic demographic change that is reflected in a progressive ageing population. If on the one side increasing health care for older people is important, stimulating the level of birth becomes decisive. The principal goal of this work is to set up of new method for early diagnosis of male infertility based on analysis of seminal Volatile Organic Compounds (VOCs), potentially biomarkers of infertility status. The identification of the volatile metabolite patterns in semen samples was done by an unconventional GC/[−MS + gas sensor] system. Once validate this approach could integrate and improve traditional semen analysis based on physiological parameters and addressed to the development of novel medical devices based on gas microsensors for male infertility screening.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Callen T, McKibbin JW, Batini N (2006) The global impact of demographic change. IMF Working Paper, pp 1–36
Inhorn MC, Patrizio P (2015) Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century. Hum Reprod Update 21(4):411–426
Jungwirth A, Giwercman A, Tournaye H, Diemer T, Kopa Z, Dohle G, Krausz C (2012) European association of urology working group on male infertility. European association of urology guidelines on male infertility: the 2012 update. Eur Urol 62(2):324–332. https://doi.org/10.1016/j.eururo.2012.04.048
Lunenfeld B, Van Steirteghem A (2004) Infertility in the third millennium: implications for the individual, family and society: Condensed Meeting Report from the Bertarelli Foundation’s second global conference. Human Reprod Update 10(4):317–326. https://doi.org/10.1093/humupd/dmh028
Pettinger T. The impact of an ageing population on the economy. https://www.economicshelp.org
UN/DESA Department of economic and social affairs population division: world population ageing (2015)
Vas G, Vékey K (2004) Solid-phase microextraction: a powerful sample preparation tool prior to mass spectrometric analysis. J Mass Spectrom 39(3):233–254
World Health Organisation (2010) WHO laboratory manual for the examination and processing of human seme, 5th edn. WHO, Geneva, Switzerland
Zhang X, Diao R, Zhu X, Li Z, Cai Z (2015) Metabolic characterization of asthenozoospermia using nontargeted seminal plasma metabolomics. Clin Chim Acta 450:254–261. https://doi.org/10.1016/j.cca.2015.09.001
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this paper
Cite this paper
Longo, V. et al. (2019). Seminal VOCs Analysis Investigating Sperm Quality Decline—New Studies to Improve Male Fertility Contrasting Population Ageing. In: Leone, A., Caroppo, A., Rescio, G., Diraco, G., Siciliano, P. (eds) Ambient Assisted Living. ForItAAL 2018. Lecture Notes in Electrical Engineering, vol 544. Springer, Cham. https://doi.org/10.1007/978-3-030-05921-7_40
Download citation
DOI: https://doi.org/10.1007/978-3-030-05921-7_40
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-05920-0
Online ISBN: 978-3-030-05921-7
eBook Packages: EngineeringEngineering (R0)