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Radiation Effects in Polymeric Materials pp 269–292Cite as

Synthesis of Hydrogels by Modification of Natural Polysaccharides Through Radiation Cross-Linking Polymerization for Use in Drug Delivery

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Part of the book series: Springer Series on Polymer and Composite Materials ((SSPCM))

Abstract

Hydrogels are three-dimensional polymer structures that can captivate and hold a vast quantity of water. They have superior’s properties such as hydrophilicity, high swelling ability, non-toxic in nature, and biocompatibility which makes them prospective materials for various applications. The concept of graft copolymers in biomedical field developed in the past few ten years and lasts to fascinate researchers working in this sector. Research in this sector is ongoing with the aim of alteration of the inherent properties of polysaccharides after grafting, which offers premises to be pervasive in integrated systems with multiple functionalities or the enhanced properties of one domain. This chapter aims to give comprehensive details about research that have been made on radiation-induced synthesis of polysaccharide-based hydrogels in context to biomedical application. This review also intends to explain the mechanism of radiation-induced synthesis of hydrogels. The effect of various radiation sources such as gamma, microwave, electron, and heavy ions is also discussed. Also, current status and plans of hydrogels are presented along with proper citations extracted from the scientific literature. Moreover, this article provides you with essential information that one’s need to start work in this area.

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Acknowledgements

One of the authors (Kashma Sharma) is grateful to the University Grants Commission (UGC), New Delhi, for the award of Post-Doctoral Fellowship for Women [F.15-1/2017/PDFWM-2017-18-HIM-51703(SA-II)].

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Authors and Affiliations

  1. Institute of Forensic Science & Criminology, Panjab University, Chandigarh, India

    Kashma Sharma & Vishal Sharma

  2. Department of Physics, National Institute of Technology, Srinagar, Hazratbal, ​190006, Jammu and Kashmir, India

    Vijay Kumar

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  1. Kashma Sharma
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  2. Vishal Sharma
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  3. Vijay Kumar
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Corresponding authors

Correspondence to Kashma Sharma or Vijay Kumar .

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Editors and Affiliations

  1. Department of Physics, National Institute of Technology (NIT), Srinagar, Jammu and Kashmir, India

    Vijay Kumar

  2. Indo-US Science and Technology Forum (IUSSTF), New Delhi, Delhi, India

    Babulal Chaudhary

  3. Institute for Forensic Science and Criminology, Panjab University, Chandigarh, India

    Vishal Sharma

  4. Department of Chemical Engineering, Indian Institute of Technology, Kanpur, Uttar Pradesh, India

    Kartikey Verma

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Sharma, K., Sharma, V., Kumar, V. (2019). Synthesis of Hydrogels by Modification of Natural Polysaccharides Through Radiation Cross-Linking Polymerization for Use in Drug Delivery. In: Kumar, V., Chaudhary, B., Sharma, V., Verma, K. (eds) Radiation Effects in Polymeric Materials. Springer Series on Polymer and Composite Materials. Springer, Cham. https://doi.org/10.1007/978-3-030-05770-1_8

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