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Vitamin E in Human Health pp 385–403Cite as

Vitamin E and Air Pollution

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Part of the book series: Nutrition and Health ((NH))

Abstract

It is estimated that over 80% of the global population is exposed to unacceptably high levels of air pollution, which can have damaging health effects. In fact, according to the most recent analysis of the global burden of diseases (2015), particulate matter (PM) air pollution exposure alone is the 5th leading risk factor for mortality worldwide, accounting for approximately 4.2 million deaths (7.6% of global deaths). Common diseases associated with both acute and chronic PM exposure include asthma, chronic obstructive pulmonary disease (COPD), respiratory infections, cardiovascular, metabolic, gastrointestinal, skin and central nervous system (CNS) diseases. While the specific mechanisms leading to the development and progression of each of these diseases vary, all have a common underlying pathology of inflammation and oxidative stress. Various nutritional interventions have been assessed for their protective effect against air pollution exposure. Dietary supplementation with vitamin E is hypothesised to be beneficial due to its antioxidant and anti-inflammatory properties. Here we review the literature on the adverse health effects of air pollution on the respiratory, cardiovascular, metabolic, gastrointestinal, skin and central nervous systems and the role of vitamin E in modifying the detrimental consequences of air pollution. While there is evidence from clinical trials regarding the benefits of combined vitamin E and C in ameliorating the effects of air pollution in asthma and reducing the risk of respiratory infections, further work is needed to assess the efficacy of vitamin E supplementation in protecting against the numerous other health consequences of air pollution exposure.

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Authors and Affiliations

  1. Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, Newcastle, NSW, Australia

    Rebecca F. McLoughlin, Bronwyn S. Berthon, Evan J. Williams & Lisa G. Wood

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  2. Bronwyn S. Berthon
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  3. Evan J. Williams
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Editors and Affiliations

  1. University of Hohenheim, Institute of Nutritional Sciences, Stuttgart , Germany

    Peter Weber

  2. University of Applied Sciences Fulda, Nutritional, Food and Consumer Sciences, Fulda, Germany

    Marc Birringer

  3. Friedman School of Nutrition Science and Policy, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA

    Jeffrey B. Blumberg

  4. University Medical Center Groningen, Hanzeplain 1, Groningen, The Netherlands

    Manfred Eggersdorfer

  5. University of Hohenheim, Institute of Nutritional Sciences, Stuttgart , Germany

    Jan Frank

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McLoughlin, R.F., Berthon, B.S., Williams, E.J., Wood, L.G. (2019). Vitamin E and Air Pollution. In: Weber, P., Birringer, M., Blumberg, J., Eggersdorfer, M., Frank, J. (eds) Vitamin E in Human Health. Nutrition and Health. Humana Press, Cham. https://doi.org/10.1007/978-3-030-05315-4_27

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