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Clinical Cardiovascular Disease Trials: The Vitamin E Case

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Vitamin E in Human Health

Part of the book series: Nutrition and Health ((NH))

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Abstract

Vitamin E is a naturally occurring fat-soluble vitamin. Its antioxidant properties have made it a popular candidate to combat oxidative stress and diseases that are caused by it. It has been widely studied as a potential treatment for both primary and secondary protection of cardiovascular disease because of its well-understood mechanism, its ability to naturally recycle itself, and its promising epidemiological evidence. After numerous prospective and retrospective clinical studies, there has been a lack of consistent evidence supporting the notion that vitamin E should be used for the primary and secondary prevention of cardiovascular disease (CVD). This chapter outlines various clinical trials that have assessed the potential clinical benefit of vitamin E to prevent CVD.

Joshua Wiener and Elliot Berinstein contributed equally to this chapter.

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    Authors and Affiliations

    1. The Ruth and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel

      Joshua B. Wiener, Elliot M. Berinstein & Andrew P. Levy

    Authors
    1. Joshua B. Wiener
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    2. Elliot M. Berinstein
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    3. Andrew P. Levy
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    Correspondence to Andrew P. Levy .

    Editor information

    Editors and Affiliations

    1. University of Hohenheim, Institute of Nutritional Sciences, Stuttgart , Germany

      Peter Weber

    2. University of Applied Sciences Fulda, Nutritional, Food and Consumer Sciences, Fulda, Germany

      Marc Birringer

    3. Friedman School of Nutrition Science and Policy, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA

      Jeffrey B. Blumberg

    4. University Medical Center Groningen, Hanzeplain 1, Groningen, The Netherlands

      Manfred Eggersdorfer

    5. University of Hohenheim, Institute of Nutritional Sciences, Stuttgart , Germany

      Jan Frank

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    Wiener, J.B., Berinstein, E.M., Levy, A.P. (2019). Clinical Cardiovascular Disease Trials: The Vitamin E Case. In: Weber, P., Birringer, M., Blumberg, J., Eggersdorfer, M., Frank, J. (eds) Vitamin E in Human Health. Nutrition and Health. Humana Press, Cham. https://doi.org/10.1007/978-3-030-05315-4_20

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    • DOI: https://doi.org/10.1007/978-3-030-05315-4_20

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    • Publisher Name: Humana Press, Cham

    • Print ISBN: 978-3-030-05314-7

    • Online ISBN: 978-3-030-05315-4

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