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Lobular Carcinoma In Situ

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Breast Disease

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Abstract

Lobular carcinoma in situ (LCIS) is a high-risk indicator lesion for and a non-obligate precursor of the development of invasive breast carcinoma. Loss of E-cadherin is the hallmark pathological feature of lobular entities. Effective clinical management of LCIS requires good communication between the radiologist, surgeon, pathologist, and medical oncologist and entails surgical excision, subsequent surveillance, and systemic and surgical strategies to reduce the risk of future invasive cancer.

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Author information

Authors and Affiliations

  1. Department of Surgery, Division of Surgical Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Priscilla McAuliffe

  2. Magee-Women’s Surgical Associates, Pittsburgh, PA, USA

    Priscilla McAuliffe

  3. Women’s Cancer Research Center of UPMC Hillman Cancer Center, Pittsburgh, PA, USA

    Priscilla McAuliffe

Authors
  1. Priscilla McAuliffe
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Correspondence to Priscilla McAuliffe .

Editor information

Editors and Affiliations

  1. Department of Medical Oncology, Istanbul Medical Faculty, Oncology Institute, Istanbul University, Istanbul, Turkey

    Adnan Aydiner

  2. Department of General Surgery, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey

    Abdullah Igci

  3. Department of Surgical Oncology, Magee-Womens Hospital of the University of Pittsburgh, Pittsburgh, PA, USA

    Atilla Soran

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McAuliffe, P. (2019). Lobular Carcinoma In Situ. In: Aydiner, A., Igci, A., Soran, A. (eds) Breast Disease. Springer, Cham. https://doi.org/10.1007/978-3-030-04606-4_7

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  • DOI: https://doi.org/10.1007/978-3-030-04606-4_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-04605-7

  • Online ISBN: 978-3-030-04606-4

  • eBook Packages: MedicineMedicine (R0)

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