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Imaging in Pediatric Oncology pp 223–252Cite as

Non-neurologic Late Effects of Therapy

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Part of the book series: Pediatric Oncology ((PEDIATRICO))

Abstract

With the overall 5-year survival of patients diagnosed with cancer during childhood and adolescence now exceeding 80%, these survivors represent a rapidly growing population who may be burdened with adverse late toxicities and chronic disease. The chapter is organized by organ systems involved and addresses many of the more common adverse non-neurologic treatment-related late effects. The mechanisms of and risk factors for their development and imaging methods for their detection are discussed.

This work was supported in part by grant number P30CA021765-38 from the National Institutes of Health, a Center of Excellence grant from the State of Tennessee, and the American Lebanese Syrian Associated Charities (ALSAC).

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Acknowledgments

The authors are grateful to Vella Laws-Bell for manuscript preparation and to Cynthia Lyle for critical review.

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Authors and Affiliations

  1. Department of Oncology, St. Jude Children’s Research Hospital, Memphis, TN, USA

    Sue C. Kaste

  2. Department of Diagnostic Imaging, St. Jude Children’s Research Hospital, Memphis, TN, USA

    Sue C. Kaste

  3. Department of Radiology, University of Tennessee Health Science Center, Memphis, TN, USA

    Sue C. Kaste & Anurag Arora

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  1. Sue C. Kaste
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  2. Anurag Arora
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Correspondence to Sue C. Kaste .

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  1. Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA

    Stephan D. Voss

  2. Department of Radiology, Great Ormond Street Hospital for Children, London, UK

    Kieran McHugh

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Kaste, S.C., Arora, A. (2019). Non-neurologic Late Effects of Therapy. In: Voss, S., McHugh, K. (eds) Imaging in Pediatric Oncology. Pediatric Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-03777-2_12

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