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Contraception and Menstrual Suppression for Adolescent and Young Adult Oncology Patients

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Textbook of Oncofertility Research and Practice

Abstract

According to the 2013 National Youth Risk Behavior Survey (YRBS) (Abma and Martinez. Natl Health Stat Report 104:1–23, 2017), 47% of high school students in the United States (USA) admitted to previous sexual intercourse, and of those, 14% did not use any method of pregnancy prevention (Brener et al. MMWR Recomm Rep (Morb Mortal Wkly Rep Recomm Rep/Centers Dis Control) 62:1–20, 2013). An unintended pregnancy during cancer treatments may result in a delay in therapy or teratogenic exposure (Committee opinion no. 607 Obstet Gynecol 124:403–408, 2014). These complications, in addition to several other psychosocial and healthcare considerations, may warrant recommendation for abortion, which can be difficult to access, further delaying important care. For many of these patients, unintended pregnancy may also be associated with an unacceptable increase in general health risk. Therefore, an open and early discussion about contraceptive needs and options is essential to the overall care of the adolescent and young adult oncology patient. Choosing a contraceptive method is an important decision with many involved factors for both patients and physicians. We must consider the efficacy and safety profile of each method, as well as how the method fits into each patient’s lifestyle, including technical, social, and religious factors, among others. In the adolescent oncology patient, these issues can compound quickly. Medically, these patients present increased challenges due to their underlying diagnoses and the increased thromboembolic risk associated with malignancy. A thorough discussion of indicated contraceptive methods should be undertaken with each patient, with focus placed on efficacy and safety. An added benefit (or alternative use) of contraceptive medications during cancer treatment has been to elicit menstrual lightening and suppression, especially in patients with low blood count, menorrhagia, and/or risk of bone marrow suppression. Additionally, every social situation is unique, and we must remember to ensure confidentiality in our adolescent patients.

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Correspondence to Holly R. Hoefgen .

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Appendices

Appendix: Medical Eligibility Criteria for Contraceptive Use

figure a
figure b
figure c
figure d

Review Questions and Answers

  1. Q1.

    Which of the following describes the CDC medical eligibility criteria for contraceptive use category 2?

    1. (a)

      A condition for which there is no restriction for the use of the contraceptive method

    2. (b)

      A condition that represents an unacceptable health risk if the contraceptive method is used

    3. (c)

      A condition for which the advantages of using the method generally outweigh the theoretical or proven risks

    4. (d)

      A condition for which the theoretical or proven risks usually outweigh the advantages of using the method

  1. A1.

    (c)

  1. Q2.

    When weighing the risks of administration of estrogen or estrogen-containing contraceptives to control acute heavy vaginal bleeding in a patient with chemotherapy-induced thrombocytopenia, we should consider…

    1. (a)

      Volume of bleeding and hemodynamic stability

    2. (b)

      Thromboembolic risks

    3. (c)

      Relative medical risks of alternative therapies

    4. (d)

      All of the above

  1. A2.

    (d)

  1. Q3.

    According to American Academy of Pediatrics (AAP) published recommendation, what is the first-line contraceptive choice for adolescents who choose not to be abstinent?

    1. (a)

      Barrier methods

    2. (b)

      Injectable contraceptive (depot medroxyprogesterone acetate – DMPA)

    3. (c)

      Long-acting reversible contraceptive (LARC)

    4. (d)

      Combined hormonal contraceptives (pill, patch, ring)

  1. A3.

    (c)

  1. Q4.

    Which of the following clinical scenarios would be a contraindication to the use of emergency contraception 1 day following unprotected intercourse?

    1. (a)

      An adolescent girl in active treatment for leukemia

    2. (b)

      A young adult woman with known liver disease

    3. (c)

      A teenage female, 2 months after BMT for sickle cell disease

    4. (d)

      There are no instances in which the risks outweigh the benefits of use

  1. A4.

    (d)

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Zeal, C., Benoit, J., Hoefgen, H.R. (2019). Contraception and Menstrual Suppression for Adolescent and Young Adult Oncology Patients. In: Woodruff, T., Shah, D., Vitek, W. (eds) Textbook of Oncofertility Research and Practice. Springer, Cham. https://doi.org/10.1007/978-3-030-02868-8_13

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