Abstract
There are many ways to better understand how to diagnose and treat our patients. An unusually powerful tool is the randomized controlled trial (RCT). The first well-reported RCT assessed utility of streptomycin for the treatment of tuberculosis in 1948 (Williams, How to critically appraise a randomized controlled trial. In: Williams H, Bigby M, Herxheimer A, Naldi L, Rzany B, Dellavale R, Ran Y, Furue E (eds) Evidence-based dermatology, 3rd edn. Wiley, New York, pp 39–45, 2014). Although a relatively newcomer to the scientific toolbox, the blinded RCT is now widely acknowledged as the key building block that underpins high-level medical evidence.
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Alam, M. (2019). Designing Randomized Clinical Trials in Dermatologic Surgery. In: Alam, M. (eds) Evidence-Based Procedural Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-02023-1_1
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