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Anesthetic Management of Thoracic Trauma

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Principles and Practice of Anesthesia for Thoracic Surgery

Abstract

Thoracic trauma is a morbid business. The American College of Surgeons estimates it is associated with a 10% mortality [1] with 16,000 deaths annually. That represents 25% of all trauma deaths. Considering that injury is the leading cause of death from ages 1 to 45 (more than half of all deaths ages 13–32 and 80% in teenage years) [2] and the leading cause of years of life lost before 75, its impact is enormous [3]. In one analysis, if injury is taken into account, the life expectancy in the United States rockets from 19th in the developed world to first [4]. Since the vital structures in the chest are so well protected by the bony thorax, a great deal of force is required to disrupt them, and they are uncommonly injured in isolation in blunt trauma. Indeed, 70% of the time, insults to the chest are associated with multisystem injury.

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References

  1. American College of Surgeons Committee on Trauma. Thoracic trauma. In: ATLS® program for doctors student course manual. 6th ed. Chicago: American College of Surgeons; 1997. p. 127–41.

    Google Scholar 

  2. Bergen G, Chen LH, Warner M, Fingerhut LA. Injury in the United States: 2007 Chartbook. Hyattsville: National Center for Health Statistics; 2008.

    Google Scholar 

  3. Fingerhaut LA, Warner M. Injury Chartbook. Health, United States, 1996–7. Hyattsville: National Center for Health Statistics; 1998.

    Google Scholar 

  4. Ohsfeldt RL, Schneider JE. The business of health. The role of competition, markets, and regulation. 1st ed. Washington DC: AEI Press; 2006.

    Google Scholar 

  5. American College of Surgeons Committee on Trauma. Thoracic trauma. In:ATLS® program for doctors student course manual. 9th ed. Chicago: American College of Surgeons; 2012. p. 94–112.

    Google Scholar 

  6. Rozycki GS, Feliciano DV, Ochsner MG, et al. The role of ultrasound in patients with possible penetrating cardiac wounds: a prospective multicenter study. J Trauma Acute Care Surg. 1999;46:543–51.

    Article  CAS  Google Scholar 

  7. Kirkpatrick AW, Ball CG, D’Armours SK, Zygun D. Acute resuscitation of the unstable adult trauma patient: bedside diagnosis and therapy. Can J Surg. 2008;5(1):57–69.

    Google Scholar 

  8. Hakuba T, Minato N, Minematsu T, Kamohara K. Surgical management and treatment of traumatic right atrial rupture. Gen Thorac Cardiovasc Surg. 2008;56(11):551–4.

    Article  PubMed  Google Scholar 

  9. Lim R, Gill IS, Temes RT, Smith CE. The use of adenosine for repair of penetrating cardiac injuries: a novel method. Ann Thoracic Surg. 2001;71:1714–5.

    Article  CAS  Google Scholar 

  10. Mowery NT, Gunter OL, Collier BR, Jose’J D Jr, Haut E, Hildreth A, Holevar M, Mayberry J, Streib E. Practice management guidelines for management of hemothorax and occult Pneumothorax. J Trauma Acute Care Surg. 2011;70(2):510–8.

    Article  Google Scholar 

  11. Clancy K, Velopulos C, Bilaniuk JW, et al. Screening for blunt cardiac injury. J Trauma Acute Care Surg. 2012;73(5):S301–6.

    Article  PubMed  Google Scholar 

  12. Karalis D, Victor M, Davis G, McAllister M, Covalesky V, Ross J, Foley R, Kerstein M, Chandrasekaran K. The role of echocardiography in blunt chest trauma. J Trauma. 1994;36(1):53–8.

    Article  CAS  PubMed  Google Scholar 

  13. Chirillo F, Totis O, Cavarzerani A, et al. Usefulness of transthoracic and transoesophageal echocardiography in recognition and management of cardiovascular injuries after blunt chest trauma. Heart. 1996;75(3):301–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Shanewise JS, Cheung AT, Aronson S, et al. ASE/SCA guidelines for performing a comprehensive intraoperative multiplane transesophageal echocardiography examination: recommendations of the American Society of Echocardiography Council for Intraoperative Echocardiography and the Society of Cardiovasc. Anesth Analg. 1999;89:870–84.

    Article  CAS  PubMed  Google Scholar 

  15. Poterack KA. Who uses transesophageal echocardiography in the operating room? Anesth Analg. 1995;80(3):454–8.

    CAS  PubMed  Google Scholar 

  16. Minhaj M, Patel K, Muzic D, et al. The effect of routine intraoperative transesophageal echocardiography on surgical management. J Cardiothorac Vasc Anesth. 2007;21(6):800–4.

    Article  PubMed  Google Scholar 

  17. Memtsoudis SG, Rosenberger P, Loffler M, et al. The usefulness of transesophageal echocardiography during intraoperative cardiac arrest in noncardiac surgery. Anesth Analg. 2006;102(6):1653–7.

    Article  PubMed  Google Scholar 

  18. Kallmeyer IJ, Collard CD, Fox JA, Body SC, Shernan SK. The safety of intraoperative transesophageal echocardiography: a case series of 7200 cardiac surgical patients. Anesth Analg. 2001;92(5):1126–30.

    Article  CAS  PubMed  Google Scholar 

  19. Reeves ST, Finley AC, Skubas NJ, et al. Basic perioperative transesophageal echocardiography examination: a consensus statement of the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists. J Am Soc Echocardiogr. 2013;26:443–56.

    Article  PubMed  Google Scholar 

  20. Thys DM, Abel MD, Brooker RF, Cahalan MK, Connis RT, Duke PG, Nickinovich DG, Reeves ST, Rozner MA, Russell IA, Streckenbach SC. Practice guidelines for perioperative transesophageal echocardiography. Anesthesiology. 2010;112(5):1084–96.

    Google Scholar 

  21. Leichtle SW, Singleton A, Singh M, Griffee MJ, Tobin JM. Transesophageal echocardiography in the evaluation of the trauma patient: a trauma resuscitation transesophageal echocardiography exam. J Crit Care. 2017;40:202–6.

    Article  PubMed  Google Scholar 

  22. Catoire P, Orliaguet G, Liu N, et al. Systemic transoesophageal echocardiography for detection of mediastinal lesions in patients with multiple injuries. J Trauma. 1995;38(1):96–8.

    Article  CAS  PubMed  Google Scholar 

  23. Mollod M, Felner JM. Transesophageal echocardiography in the evaluation of cardiothoracic trauma. Am Heart J. 1996;132(4):841–9.

    Article  CAS  PubMed  Google Scholar 

  24. Griffee MJ, Singleton A, Zimmerman JM, Morgan DE. The effect of perioperative rescue transesophageal echocardiography on the management of trauma patients. Anesth Analg. 2016;6(12):387–90.

    Google Scholar 

  25. Markin NW, Gmelch BS, Griffee MJ, Holmberg TJ, Morgan DE, Zimmerman JM. A review of 364 perioperative rescue echocardiograms: findings of an anesthesiologist-staffed perioperative echocardiography service. J Cardiothorac Vasc Anesth. 2015;29(1):82–8.

    Article  PubMed  Google Scholar 

  26. Porter TR, Shillcutt SK, Adams MS, et al. Guidelines for the use of echocardiography as a monitor for therapeutic intervention in adults: a report from the American Society of Echocardiography. J Am Soc Echocardiogr. 2015;28(1):40–56.

    Article  PubMed  Google Scholar 

  27. Shillcutt SK, Markin NW, Montzingo CR, Brakke TR. Use of rapid “rescue” perioperative echocardiography to improve outcomes after hemodynamic instability in noncardiac surgical patients. J Cardiothorac Vasc Anesth. 2012;26(3):362–70.

    Article  PubMed  Google Scholar 

  28. Kaye P, O’Sullivan I. Myocardial contusion: emergency investigation and diagnosis. Emerg Med J. 2002;19(1):8–10.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Sousa RC, Garcia-Fernandez MA, Moreno M, Quero F, Torrecilla E, San Roman D, Delcan JL. Value of transesophageal echocardiography in the assessment of blunt chest trauma: correlation with electrocardiogram, heart enzymes, and transthoracic echocardiogram. Rev Port Cardiol. 1994;13(11):833–43. 807-8.

    CAS  PubMed  Google Scholar 

  30. Orliaguet G, Ferjani M, Riou B. The heart in blunt trauma. Anesthesiology. 2001;95:544–8.

    Article  CAS  PubMed  Google Scholar 

  31. Maenza RL, Seaberg D, D’Amico F. A meta-analysis of blunt cardiac trauma: ending myocardial confusion. Am J Emerg Med. 1996;14(3):237–41.

    Article  CAS  PubMed  Google Scholar 

  32. Yousef R, Carr JA. Blunt cardiac trauma: a review of the current knowledge and management. Ann Thorac Surg. 2014;98(3):1134–40.

    Article  PubMed  Google Scholar 

  33. Ouda A, Kappert U, Ghazy T, et al. Isolated rupture of the right upper pulmonary vein: a blunt cardiac trauma case. Ann Thorac Surg. 2011;91(4):1267–9.

    Article  PubMed  Google Scholar 

  34. Rowe SK, Porter CB. Atrial septal hematoma: two-dimensional echocardiographic findings after blunt chest trauma. Am Heart J. 1987;114(3):650–2.

    Article  CAS  PubMed  Google Scholar 

  35. Fegheli NT, Prisant LM. Blunt myocardial injury. Chest. 1995;108:1673–7.

    Article  Google Scholar 

  36. Shapiro M, Yanofski S, Trapp J, et al. Cardiovascular evaluation in blunt thoracic trauma using Transesophageal Echocardiography (TEE). J Trauma. 1991;31(6):835–40.

    Article  CAS  PubMed  Google Scholar 

  37. Brooks SW, Young JC, Cmolik B, et al. The use of transesophageal echocardiography in the evaluation of chest trauma. J Trauma. 1992;32(6):761–6.

    Article  CAS  PubMed  Google Scholar 

  38. Zakynthinos EG, Vassilakopoulos T, Routsi C, Roussos C, Zakynthinos S. Early- and late-onset atrioventricular valve rupture after blunt chest trauma: the usefulness of transesophageal echocardiography. J Trauma. 2002;52(5):990–6.

    PubMed  Google Scholar 

  39. Varahan SL, Farah GM, Caldeira CC, Hoit BD, Askari AT. The double jeopardy of blunt chest trauma: a case report and review. Echocardiography. 2006;23(3):235–9.

    Article  PubMed  Google Scholar 

  40. Bruschi G, Agati S, Iorio F, Vitali E. Papillary muscle rupture and pericardial injuries after blunt chest trauma. Eur J Cardiothorac Surg. 2001;20(1):200–2.

    Article  CAS  PubMed  Google Scholar 

  41. Nelson M, Wells G. A case of traumatic tricuspid valve regurgitation caused by blunt chest trauma. J Am Soc Echocardiogr. 2007;20(2):198.e4–5.

    Article  Google Scholar 

  42. Ellis JE, Bender EM. Intraoperative transesophageal echocardiography in blunt thoracic trauma. J Cardiothorac Vasc Anesth. 1991;5(4):373–6.

    Article  CAS  PubMed  Google Scholar 

  43. Kennedy N, Ireland M, McConaghy P. Transoesophageal echocardiographic examination of a patient with venacaval and pericardial tears after blunt chest trauma. Br J Anaesth. 1995;75:495–7.

    Article  CAS  PubMed  Google Scholar 

  44. De Maria E, Gaddi O, Navazio A, Monducci I, Tirabassi G, Guiducci U. Right atrial free wall rupture after blunt chest trauma. J Cardiovasc Med (Hagerstown). 2007;8(11):946–9.

    Article  Google Scholar 

  45. Nandate K, Krishnamoorthy V, McIntyre LK, Verrier ED, Mackensen GB. Gunshot-induced aorto-left atrial fistula diagnosed by intraoperative transesophageal echocardiography. Ann Thorac Surg. 2016;101(2):771–3.

    Article  PubMed  Google Scholar 

  46. Rudski LG, Lai WW, Afilalo J, et al. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography. J Am Soc Echocardiogr. 2010;23(7):685–713.

    Article  PubMed  Google Scholar 

  47. Lang RM, Bierig M, Devereux RB, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s guidelines and standards committee and the chamber quantification writing group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr. 2005;18(12):1440–63.

    Article  PubMed  Google Scholar 

  48. Reichert CLA, Visser CA, van den Brink RBA, et al. Prognostic value of biventricular function in hypotensive patients after cardiac surgery as assessed by transesophageal echocardiography. J Cardiothorac Vasc Anesth. 1992;6(4):429–32.

    Article  CAS  PubMed  Google Scholar 

  49. Vignon P, Gueret P, Vedrinne JM, Lagrange P, Cornu E, Abrieu O, Gastinne H, Bensaid J, Lang R. Role of transesophageal echocardiography in the diagnosis and management of traumatic aortic disruption. Circulation. 1995;92(10):2959–68.

    Article  CAS  PubMed  Google Scholar 

  50. Vignon P, Boncoeur MP, François B, Rambaud G, Maubon A, Gastinne H. Comparison of multiplane transesophageal echocardiography and contrast-enhanced helical CT in the diagnosis of blunt traumatic cardiovascular injuries. Anesthesiology. 2001;94(4):615–22.

    Article  CAS  PubMed  Google Scholar 

  51. Saranteas T, Mavrogenis AF, Mandila C, Poularas J, Panou F. Ultrasound in cardiac trauma. J Crit Care. 2017;38:144–51.

    Article  PubMed  Google Scholar 

  52. Lanigan MJ, Chaney MA, Gologorsky E, Chavanon O, Augoustides JG. CASE 2 – 2014: aortic dissection: real or artifact? J Cardiothorac Vasc Anesth. 2014;28(2):398–407.

    Article  PubMed  Google Scholar 

  53. Ahrar K, Smith DC, Bansal RC, Razzouk A, Catalano RD. Angiography in blunt thoracic aortic injury. J Trauma. 1997;42(4):665–9.

    Article  CAS  PubMed  Google Scholar 

  54. Bansal V, Lee J, Coimbra R. Current diagnosis and management of blunt traumatic rupture of the thoracic aorta. J Vasc Bras. 2007;6(1):64–73.

    Article  Google Scholar 

  55. Le Bret F, Ruel P, Rosier H, Goarin JP, Riou B, Viars P. Diagnosis of traumatic mediastinal hematoma with transesophageal echocardiography. Chest. 1994;105(2):373–6.

    Article  PubMed  Google Scholar 

  56. Vignon P, Rambaud G, François B, Preux P-M, Lang RM, Gastinne H. Quantification of traumatic hemomediastinum using transesophageal echocardiography. Chest. 1998;113(6):1475–80.

    Article  CAS  PubMed  Google Scholar 

  57. Hahn RT, Abraham T, Adams MS, et al. Guidelines for performing a comprehensive transesophageal echocardiographic examination: recommendations from the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists. Anesth Analg. 2014;118(1):21–68.

    Article  PubMed  Google Scholar 

  58. Neskovic AN, Hagendorff A, Lancellotti P, et al. Emergency echocardiography: the European Association of Cardiovascular Imaging recommendations. Eur Heart J Cardiovasc Imaging. 2013;14(1):1–11.

    Article  PubMed  Google Scholar 

  59. Levitov A, Frankel HL, Blaivas M, et al. Guidelines for the appropriate use of bedside general and cardiac ultrasonography in the evaluation of critically ill patients—part II. Crit Care Med. 2016;44(6):1206–27.

    Article  PubMed  Google Scholar 

  60. Santoni BG, Hindman BJ, Puttit CM, Weeks JB, Johnson N, Maktabi MA, Todd MM. Manuel in-line stabilization increases pressures applied by the laryngoscope blade during direct laryngoscopy and orotracheal intubation. Anesthesiology. 2009;110:24–31.

    Article  PubMed  Google Scholar 

  61. Manoach S, Paladino L. Laryngoscopy force, visualization and intubation failure in acute trauma. Anesthesiology. 2009;110:6–7.

    Article  PubMed  Google Scholar 

  62. Rice MJ, Mancuso AA, Gibbs C, Morey TE, Gravenstein N, Deitte LA. Cricoid pressure results in compression of the postcricoid hypopharynx: the esophageal position is irrelevant. Anesth Analg. 2009;109:1546–52.

    Article  PubMed  Google Scholar 

  63. Ovassapian A, Salem MR. Sellick’s maneuver: to do or not to do. Anesth Analg. 2009;109:1360–2.

    Article  PubMed  Google Scholar 

  64. Lerman J. On cricoid pressure: “may the force be with you”. Anesth Analg. 2009;109:1363–6.

    Article  PubMed  Google Scholar 

  65. Priebe HJ. Cricoid pressure: an alternative view. Semin Anesth. 2005;24(2):120–6.

    Google Scholar 

  66. Birenbaum A, Hajage D, Roche S, et al. Effect of cricoid pressure compared with a sham procedure in the rapid sequence induction of anesthesia: the IRIS randomized clinical trial. JAMA Surg. 2018; https://doi.org/10.1001/jamasurg.2018.3577.

  67. Hagberg CA, Kaslow O. Difficult airway management in trauma updated by COTEP. ASA Monitor. 2014;78(9):56–60.

    Google Scholar 

  68. Crosby ET. Airway management in adults after cervical spine trauma. Anesthesiology. 2006;104:1293–318.

    Article  PubMed  Google Scholar 

  69. Shatney CH, Brunner RD, Nguyen TQ. The safety of orotracheal intubation in patients with unstable cervical spine fracture or high spinal cord injury. Am J Surg. 1995;170:676–80.

    Article  CAS  PubMed  Google Scholar 

  70. Stephens CT, Kahntroff S, Dutton RP. The success of emergency endotracheal intubation in trauma patients: a 10-year experience at a major adult trauma referral center. Anesth Analg. 2009;109:866–72.

    Article  PubMed  Google Scholar 

  71. Campos JH, Hallam EA, Van Natta T, Kernstine KH. Devices for lung isolation used by anesthesiologists with limited thoracic experience. Anesthesiology. 2006;104:261–6.

    Article  PubMed  Google Scholar 

  72. Narayanaswamy M, McRae K, Slinger P, Dugas G, Kanellakos GW, Roscoe A, Lacroix M. Choosing a lung isolation device for thoracic surgery: a randomized trial of three bronchial blockers and double lumen tubes. Anesth Analg. 2009;108:1097–01.

    Article  CAS  PubMed  Google Scholar 

  73. Ehrenfeld JM, Walsh JL, Sandberg WA. Right- and left-sided Mallinckrodt double-lumen tubes have identical clinical performance. Anesth Analg. 2008;106:1847–52.

    Article  PubMed  Google Scholar 

  74. Kemmerer WT, Eckert WG, Gathright JB, Reemtsma k CO. Patterns of thoracic injuries in fatal traffic accidents. J Trauma. 1961;1:595–9.

    Article  CAS  PubMed  Google Scholar 

  75. Kummer C, Netto FS, Rizoli S, Yee D. A review of traumatic airway injuries: potential implications for airway assessment and management. Injury Int J Care Injured. 2007;38:27–33.

    Article  Google Scholar 

  76. Rossbach MM, Johnson SB, Gomez MA, Sako EY, Miller L, Calhoon JH. Management of tracheobronchial injuries: a 28-year experience. Ann Thorac Surg. 1998;65:182–6.

    Article  CAS  PubMed  Google Scholar 

  77. Kisser AC, Obrien SM, Detterbeck FC. Blunt tracheobronchial injuries: treatment and outcomes. Ann Thorac Surg. 2001;71:2059–65.

    Article  Google Scholar 

  78. Shah AS, Forbess JM, Skaryak LA, Lilly RE, Vaslef SN, D’Amico TA. Emergent thoracotomy for airway control after intrathoracic tracheal injury. J Trauma. 2000;48(6):1163–4.

    Article  CAS  PubMed  Google Scholar 

  79. Naghibi K, Hashemi SL, Sajedi P. Anesthetic management of tracheobronchial rupture following blunt chest trauma. Acta Anaesthesiol Scand. 2003;47:901–3.

    Article  CAS  PubMed  Google Scholar 

  80. Symbas PN, Justicz AG, Ricketts RR. Rupture of the airways from blunt trauma: treatment of complex injuries. Ann Thorac Surg. 1992;54:177–83.

    Article  CAS  PubMed  Google Scholar 

  81. Shweikh AM, Nadkarni AB. Laryngotracheal separation with pneumopericardium after a blunt trauma to the neck. Emerg Med J. 2001;18:410–1.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  82. Gómez-Caro A, Ausín P, et al. Role of conservative medical management of tracheobronchial injuries. J Trauma. 2006;61:1426–35.

    Article  PubMed  Google Scholar 

  83. Borasio P, Arissone F, Chiampo G. Post-intubation tracheal rupture. A report on ten cases. Eur J Cardiothorac Surg. 1997;12:98–100.

    Article  CAS  PubMed  Google Scholar 

  84. Parmley LF, Mattingly TW, Manion WC, Jahnke EJ Jr. Nonpenetrating traumatic injury of the aorta. Circulation. 1958;17:1086–101.

    Article  CAS  PubMed  Google Scholar 

  85. Schulman CI, Carvajal D, Lopez PP, Soffer D, Habib F, Augenstein J. Incidence and crash mechanisms of aortic injury during the past decade. J Trauma. 2007;62:664–7.

    Article  PubMed  Google Scholar 

  86. Bruno VD, Batchelor TJP. Late aortic injury: a rare complication of a posterior rib fracture. Ann Thorac Surg. 2009;87:301–3.

    Google Scholar 

  87. Neschis DG, Scalea TM, Flinn WR, Griffith BP. Blunt aortic injury. N Engl J Med. 2008;359:1708–16.

    Google Scholar 

  88. Fabian TC, Richardson JD, Croce MA, Smith JS Jr, Rodman G Jr, Kearney PA, et al. Prospective study of blunt aortic injury: multicenter trial of the American Association for the surgery of trauma. J Trauma. 1997;42:374–80.

    Google Scholar 

  89. Fabian TC, Davis KA, Gavant ML, et al. Prospective study of blunt aortic injury; helical CT is diagnostic and antihypertensive therapy reduces rupture. Ann Surg. 1998;227:666–76.

    Google Scholar 

  90. Malhotra AK, Fabian TC, Croce MA, Weinman DS, Gavant ML, Pate JW. Minimal aortic injury: a lesion associated with advancing diagnostic techniques. J Trauma. 2001;51:1042–8.

    Google Scholar 

  91. Hirose H, Gill IS, Malangoni MA. Nonoperative management of traumatic aortic injury. J Trauma. 2006;60:597–601.

    Google Scholar 

  92. Coselli JS, LeMaire SA, Köksoy C, Schmittling ZC, Curling PE. Cerebrospinal fluid drainage reduces paraplegia after thoracoabdominal aortic aneurysm repair: results of a randomized clinical trial. J Vasc Surg. 2002;35:631–9.

    Google Scholar 

  93. Feezor RJ, Hess PJ, Martin TD, Klodell CT, Beaver TM, Lottenberg L, Martin LC, Lee WA. Endovascular treatment of traumatic aortic injuries. J Am Coll Surg. 2009;208:510–6.

    Google Scholar 

  94. Lettinga-van de Poll T, Schurink GWH, DeHaan MW, Verbruggen JPAM, Jacobs MJ. Endovascular treatment of traumatic rupture of the thoracic aorta. Br J Surg. 2007;94:525–33.

    Google Scholar 

  95. Ehrlich MP, Rosseau H, Heijman R, Piquet P, Beregi JP, Nienaber CA, Sodeck G, Fattori R. Early outcome of endovascular repair of acute traumatic aortic injuries: the talent thoracic retrospective registry. Ann Thorac Surg. 2009;88:1258–66.

    Google Scholar 

  96. Reed AB, Thompson JK, Grafton CJ, Delvecchio C, Giglia JS. Timing of endovascular repair of blunt traumatic thoracic transections. J Vasc Surg. 2006;43:684–8.

    Google Scholar 

  97. Demetriades D, Velmahos GC, Scalea TM, et al. Operative repair or endovascular stent graft in blunt traumatic thoracic aortic injuries: results of an American association for the surgery of trauma multicenter study. J Trauma. 2008;64:561–70.

    Google Scholar 

  98. Demetriades D, Velmahos GC, Scalea TM, et al. Diagnosis and treatment of blunt thoracic aortic injuries: changing perspectives. J Trauma. 2008;64:1415–8.

    Google Scholar 

  99. Pang D, Hildebrand D, Bachoo P. Thoracic Endovascular Repair (TEVAR) versus open surgery for blunt traumatic thoracic aortic injury. Cochrane Database Syst Rev. 2015;(9):CD006642.

    Google Scholar 

  100. Lee AW, Matsumura JS, Mitchell RS, Farber MA, Greenberg RK, Azizzadeh A, Murad MH, Fairman RM. Endovascular repair of traumatic thoracic aortic injury: clinical practice guidelines of the Society for Vascular Surgery. J Vast Surg. 2011;53:187–92.

    Article  Google Scholar 

  101. DuBose JJ, Leake SS, Brennar M, Pasley J, O’Callaghan T, Luo-Owen X, et al. Contemporary management and outcomes of blunt thoracic aortic injury: a multi center retrospective study. J Trauma Acute Care Surg. 2015;78(2):360–9.

    Article  PubMed  Google Scholar 

  102. Devitt JH, McLean RF, Koch JP. Anaesthetic management of acute blunt thoracic trauma. Can J Anaesth. 1991;308:506–10.

    Article  Google Scholar 

  103. Leone M, Brégeon F, Antonini F, et al. Long term outcome in chest trauma. Anesthesiology. 2008;109:864–71.

    Google Scholar 

  104. Soldati G, Testa A, Silva FR, et al. Chest ultrasonography in lung contusion. Chest. 2006;130:533–8.

    Google Scholar 

  105. Ball CG, Ranson MK, Rodriguez-Galvez M, Lall R, Kirkpatrick AW. Sonographic depiction of posttraumatic alveolar-interstitial disease: the hand held diagnosis of a pulmonary contusion. J Trauma. 2009;66:962.

    Google Scholar 

  106. Hoth JJ, Stitzel JD, Gayzik S, Brownlee NA, Miller PR, Yoza BK, McCall CE, Meredith JW, Payne RM. The pathogenesis of pulmonary contusion: an open chest model in the rat. J Trauma. 2006;61:32–45.

    Google Scholar 

  107. Keel M, Ecknauer E, Stocker R, et al. Different pattern of local and systemic release of proinflammatory and anti-inflammatory mediators in severely injured patients with chest trauma. J Trauma. 1996;40:907–12.

    Google Scholar 

  108. Keel M, Trentz O. Pathophysiology of polytrauma. Injury. 2005;36:691–709.

    Google Scholar 

  109. Muehlstedt SG, Richardson CJ, Lyte M, Rodriguez JL. Systemic and pulmonary effector cell function after injury. Crit Care Med. 2002;30:1322–6.

    Google Scholar 

  110. Perl M, Gebhard F, Brückner UB, Ayala A, Braumüller C, Kinzl L, Knöferl MW. Pulmonary contusion causes impairment of macrophage and lymphocyte immune function and increases mortality associated with a subsequent septic challenge. Crit Care Med. 2005;33(6):1351–8.

    Google Scholar 

  111. Knöferl MW, Liener UC, Perl M, et al. Blunt chest trauma induces delayed splenic immunosupression. Shock. 2004;22:51–6.

    Google Scholar 

  112. Simon B, Ebert J, Bokhari F, Capella J, Emhoff T, et al. EAST practice management workgroup for pulmonary contusion-flail chest. Eastern Association for the Surgery of Trauma. 2006. www.east.org/tpg/pulmcontflailchest.pdf.

  113. Schreiter D, Reske A, Stichert B, Seiwerts M, et al. Alveolar recruitment in combination with sufficient positive end-expiratory pressure increases oxygenation and lung aeration in patients with severe chest trauma. Crit Care Med. 2004;32(4):968–75.

    Google Scholar 

  114. Kelly ME, Miller PR, Greenshaw JJ, Fabian TC, Proctor KG. Novel resuscitation strategy for pulmonary contusion after severe chest trauma. J Trauma. 2003;55:94–105.

    Google Scholar 

  115. Jacobs JV, Hooft NM, Robinson BR, et al. The use of extracorporeal membrane oxygenation in blunt thoracic trauma: a study of the extracorporeal life support organization database. J Trauma Acute Care Surg. 2015;79(6):1049–54.

    Article  CAS  PubMed  Google Scholar 

  116. Maron BJ, Gohman TE, Kyle SB, Estes NA, Link MS. Clinical profile and spectrum of commotion cordis. JAMA. 2002;287:1142–6.

    Google Scholar 

  117. Link MS, Wang PJ, Pandian NG, et al. An experimental model of sudden death due to low-energy chest-wall impact (commotion cordis). N Engl J Med. 1998;338:1805–11.

    Google Scholar 

  118. Robert E, de la Coussaye JE, Aya AGM, Bertinchant JP, Polge A, Fabbro-Péray P, Pignodel C, Eledjam JJ. Mechanisms of ventricular arrhythmias induced by myocardial contusion. Anesthesiology. 2000;92:1132–43.

    Google Scholar 

  119. Sakka SG, Huettermann E, Giebe W, Reinhart K. Late cardiac arrhythmias after blunt chest trauma. Intensive Care Med. 2000;26:792–5.

    Google Scholar 

  120. Teixeria PG, Georgiou C, Inaba K, et al. Blunt cardiac trauma: lessons learned from the medical examiner. J Trauma. 2009;67:1259–64.

    Google Scholar 

  121. Sisley AC, Rozycki GS, Ballard RN, et al. Rapid detection of traumatic effusion using surgeon performed ultrasonography. J Trauma. 1998;44(2):291–6.

    Google Scholar 

  122. Rozycki GS, Feliciano DV, Oschner MG, et al. The role of surgeon performed ultrasound in patients with possible cardiac wounds. Ann Surg. 1996;223(6):737–44.

    Google Scholar 

  123. Pasquale MD, Nagy K, Clark J. Practice management guidelines for the screening of blunt cardiac injury. Eastern Association for the Surgery of Trauma. 1998. Available on URL www.east.org/tpg/chap2.pdf. Accessed 1/1/2010.

  124. Christensen MA, Sutton KR. Myocardial contusion: new concepts in diagnosis and management. Am J Crit Care. 1993;2(1):28–34.

    Google Scholar 

  125. Lindstaedt M, Germing A, Lawo T, et al. Acute and long-term clinical significance of myocardial contusion following blunt thoracic trauma: results of a prospective study. J Trauma. 2002;52:479–85.

    Google Scholar 

  126. Velmahos GC, Karaiskakis M, Salim A, Toutouzas KG, Murray J, Asensio J, Demetriades D. Normal electrocardiography and serum troponin I levels preclude the presence if clinically significant cardiac injury. J Trauma. 2003;54:45–51.

    Google Scholar 

  127. Schultz JM, Trunkey DD. Blunt cardiac injury. Crit Care Clin. 2004;20(1):57–70.

    Google Scholar 

  128. Parmley LF, Manion WC, Mattingly TW. Nonpenetrating traumatic injury of the heart. Circulation. 1958;18(3):371–96.

    Google Scholar 

  129. Jeon Y, Ryu JH, Lim YJK, Kim CSB, Bahk JH, Yoon SZ, Choi JY. Comparative effects of vasopressin and norepinephrine after milrinone-induced hypotension in off-pump coronary artery bypass surgical patients. Eur J Cardiothoracic Surg. 2006;29(6):952–6.

    Google Scholar 

  130. Ziegler DW, Agarwal NN. The morbidity and mortality of rib fractures. J Trauma. 1994;37(6):975–9.

    Article  CAS  PubMed  Google Scholar 

  131. Clark GC, Schecter WP, Trunkey DD. Variables affecting outcome in blunt chest trauma: flail chest vs. pulmonary contusion. J Trauma. 1988;28:298–304.

    Article  CAS  PubMed  Google Scholar 

  132. Barnea Y, Kashtan H, shornick Y, Werbin N. Isolated rib fractures in elderly patients; mortality and morbidity. Can J Surg. 2002;45:43–6.

    PubMed  PubMed Central  Google Scholar 

  133. Bulger EM, Arenson MA, Mock CN, Jurkovich GJ. Rib fractures in the elderly. J Trauma. 2000;48(6):1040–7.

    Article  CAS  PubMed  Google Scholar 

  134. Simon BJ, Cushman J, Barraco R, et al. For the EAST practice management guidelines work group. Pain management guidelines for blunt thoracic trauma. J Trauma. 2005;59:1256–67.

    Article  PubMed  Google Scholar 

  135. Kasotakis G, Hasenboehler EA, Streib EW, Patel N, Patel MB, Alarcon L, Bosarge PL, Love J, Haut ER, Como JJ. Operative fixation of rib fractures after blunt trauma: a practice management guideline from the Eastern Association for the Surgery of Trauma. J Trauma Acute Care Surg. 2017;82(3):618–26.

    Article  PubMed  Google Scholar 

  136. Davignon K, Kwo J, Bigatello LM. Pathophysiology and management of the flail chest. Minerva Anestesiol. 2004;70:193–9.

    CAS  PubMed  Google Scholar 

  137. Roberts S, Skinner D, Biccard B, Rodseth RN. The role of non-invasive ventilation in blunt chest trauma: systemic review and meta-analysis. Eur J Trauma Emerg Surg. 2014;40:553–9.

    Article  CAS  PubMed  Google Scholar 

  138. Proctor H, London PS. The stove-in chest with paradoxical respiration. Br J Surg. 1955;42(176):622–33.

    Article  CAS  PubMed  Google Scholar 

  139. Enderson BL, Abdalla R, Frame SB, Casey MT, Gould H, Maull KI. Tube thoracotomy for occult pneumothorax; a prospective randomized study of its use. J Trauma. 1993;35:726–9.

    Article  CAS  PubMed  Google Scholar 

  140. Brasel KJ, Stafford RE, Wiegelt JA, Tenquist JE, Borgstrom DC. Treatment of occult pneumothoraces from blunt trauma. J Trauma. 1999;46:987–90.

    Article  CAS  PubMed  Google Scholar 

  141. Harcke HT, Mabry RL, Mazuchowski EL. Needle thoracentesis decompression: observations from postmortem computed tomography and autopsy. J Spec Oper Med. 2013;13:53–6.

    PubMed  Google Scholar 

  142. DuBose J, Inaba K, Demetriades D, Scalea TM, O’Connor J, Menaker J, Morales C, Konstantinidis A, Shiflett A, Copwood B, AAST retained hemoythroax study group. Management of post-traumatic retained hemothorax: a prospective, observational, multicenter AAST study. J Trauma Acute Care Surg. 2011;72(1):11–24.

    Article  Google Scholar 

  143. Mackersie RC, Karagianes TG, Hoyt DB, Davis JW. Prospective evaluation of epidural and intravenous administration of fentanyl for pain control and restoration of ventilator function following multiple rib fractures. J Trauma. 1991;31(4):443–51.

    Article  CAS  PubMed  Google Scholar 

  144. Knottenbelt JD, James MF, Bloomfield M. Intrapleural bupivacaine analgesia in chest trauma: a randomized double-blind controlled trial. Injury. 1991;22(2):114–6.

    Article  CAS  PubMed  Google Scholar 

  145. Lunchette FA, Radafshar SM, Kaiser R, Flynn W, Hassett JM. Prospective evaluation of epidural versus intrapleural catheters for analgesia in chest wall trauma. J Trauma. 1994;36(6):865–70.

    Article  Google Scholar 

  146. Short K, Scheeres D, Mlakar J, et al. Evaluation of intrapleural analgesia in the management of blunt traumatic chest wall pain: a clinical trial. Am Surg. 1996;62:488–93.

    CAS  PubMed  Google Scholar 

  147. el-Baz N, Faber LP, Ivankovich AD. Intrapleural infusion of local anesthetic: a word of caution. Anesthesiology. 1988;68:809–10.

    Article  CAS  PubMed  Google Scholar 

  148. Lauder GR. Interpleural analgesia and phrenic nerve palsy. Anaesthesia. 1993;48:315–6.

    Article  CAS  PubMed  Google Scholar 

  149. Parkinson SK, Mueller JB, Rich TJ, Little WL. Unilateral Horner’s syndrome associated with interpleural catheter injection of local anesthetic. Anesth Analg. 1989;68:61–2.

    CAS  PubMed  Google Scholar 

  150. Shinohara K, Iwama H, Akama Y, Tase C. Interpleural block for patients with multiple rib fractures: comparison with epidural block. J Emerg Med. 1994;12:441–6.

    Article  CAS  PubMed  Google Scholar 

  151. Karmakar MK, Ho AM. Acute pain management of patients with multiple fractured ribs. J Trauma. 2003;54:615–25.

    Article  PubMed  Google Scholar 

  152. Moore KL, Dalley AF. Thorax. In: Kelly PJ, editor. Clincially oriented anatomy. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 1999. p. 59–173.

    Google Scholar 

  153. Pedersen VM, Schulze S, Hoier-Madsen K, Halkier E. Air flow meter assessment of the effect of intercostals nerve blockade on respiratory function in rib fractures. Acta Chir Scand. 1983;149:119–20.

    CAS  PubMed  Google Scholar 

  154. Toledo-Pereyra LH, DeMeester TR. Prospective randomized evaluation of intrathoracic nerve block with bupivacaine on postoperative ventilator function. Ann Thor Surg. 1979;27:203–5.

    Article  CAS  Google Scholar 

  155. Kaplan JA, Miller ED, Gallagher EG. Postoperative analgesia of thoracotomy patients. Anesth Analg. 1975;54:773–7.

    CAS  PubMed  Google Scholar 

  156. Shanti CM, Carlin AM, Tyburski JG. Incidence of pneumothorax from intercostals nerve blocks for analgesia in rib fractures. J Trauma. 2001;51:536–9.

    CAS  PubMed  Google Scholar 

  157. Baxter AD, Flynn JF, Jennings FO. Continuous intercostal nerve blockade. Br J Anaesth. 1984;56:665–6.

    Article  Google Scholar 

  158. Mowbray A, Wong KK, Murray JM. Intercostal catheterization; an alternative approach to the paravertebral space. Anaesthesia. 1987;42:959–61.

    Article  Google Scholar 

  159. Slinger P. Informal poll taken at thoracic conference. MD Anderson Cancer center, Houston, Nov 2008.

    Google Scholar 

  160. Gerner P. Postthoracotomy pain management problems. Anesthesiol Clin. 2008;26:355–67.

    Article  PubMed  PubMed Central  Google Scholar 

  161. Conlon NP, Shaw AD, Grichnik KP. Postthoracotomy paravertebral analgesia: will it replace epidural analgesia? Anesthesiol Clin. 2008;26:369–80.

    Article  PubMed  Google Scholar 

  162. Mohta M, Verma P, Saxena AK, Sethi AK, Tyagi A, Girotra G. Prospective, randomized comparison of continuous thoracic epidural and thoracic paravertebral infusion in patients with unilateral multiple fractured ribs- a pilot study. J Trauma. 2009;66:1096–101.

    Article  PubMed  Google Scholar 

  163. Davies RG, Myles PS, Graham JM. A comparison of the analgesic efficacy and side-effects of paravertebral vs epidural blockade for thoracotomy- a systematic review and meta-analysis of randomized trials. Br J Anaesth. 2006;96:418–26.

    Article  CAS  PubMed  Google Scholar 

  164. Karmakar MK, Critchley LAH, Ho AMH, Gin T, Lee TW, Yin APC. Continuous thoracic paravertebral infusion of bupivacaine for pain management in patients with multiple fractured ribs. Chest. 2003;123:424–31.

    Article  PubMed  Google Scholar 

  165. Bulger EM, Edwards T, Klotz P, Jurkovich GJ. Epidural analgesia improves outcome after multiple rib fractures. Surgery. 2004;136:426.

    Article  PubMed  Google Scholar 

  166. Shibata Y, Nishiwaki K. Ultrasound-guided intercostals approach to thoracic paravertebral block. Anesth Analg. 2009;109(3):996–7.

    Article  PubMed  Google Scholar 

  167. Ben-Ari A, Moreno M, Chelly JE, Bigeleisen PE. Ultrasound-guided paravertebral block using an intercostals approach. Anesth Analg. 2009;109(5):1691–4.

    Article  PubMed  Google Scholar 

  168. Hara K, Sakura S, Nomura T, Saito Y. Ultrasound guided thoracic paravertebral block in breast surgery. Anaesthesia. 2009;64(2):223–5.

    Article  CAS  PubMed  Google Scholar 

  169. Lönnqvist PA, MacKenzie J, Soni AK, Conacher ID. Paravertebral blockade. Failure rate and complications. Anaesthesia. 1995;50(9):813–5.

    Article  PubMed  Google Scholar 

  170. Evans PJ, Lloyd JW, Wood GJ. Accidental intrathecal injection of bupivacaine and dextran. Anaesthesia. 1981;36:685–7.

    Article  CAS  PubMed  Google Scholar 

  171. Sharrock NE. Postural headache following thoracic somatic paravertebral block. Anesthesiology. 1980;52:360–2.

    Article  CAS  PubMed  Google Scholar 

  172. Khalil AE, Abdallah NM, Bashandy GM, Kaddah TA. Ultrasound-guided serratus anterior plane block versus thoracic epidural analgesia for thoracotomy pain. J Cardiothorac Vasc Anesth. 2017;31(1):152–8.

    Article  PubMed  Google Scholar 

  173. Worthley LI. Thoracic epidural management of chest trauma. Intensive Care Med. 1985;11:312–5.

    Article  CAS  PubMed  Google Scholar 

  174. Ullman DA, Wimpy RE, Fortune JB, Kennedy TM, Greenhouse BB. The treatment of patients with multiple rib fractures using continuous thoracic epidural narcotic infusion. Regional Anesth. 1989;14:43–7.

    CAS  Google Scholar 

  175. Dittman M, Keller R, Wolff G. A rationale for epidural analgesia in the treatment of multiple rib fractures. Intensive Care Med. 1978;4:193–7.

    Article  Google Scholar 

  176. Ueda K, Ueda W, Manabe M. A comparative study of sequential epidural bolus technique and continuous epidural infusion. Anesthesiology. 2005;103:126–9.

    Article  PubMed  Google Scholar 

  177. Halpern SH, Carvalho B. Patient-controlled epidural analgesia for labor. Anesth Analg. 2009;108:921–8.

    Article  CAS  PubMed  Google Scholar 

  178. Joshy GP, Bonnet F, Shah R, Wilkinson RC, Camu F, et al. A systematic review of randomized trials evaluating regional techniques for postthoracotomy analgesia. Anesth Analg. 2008;107:1026–40.

    Article  CAS  Google Scholar 

  179. Moon MR, Luchette FA, Gibson SW, et al. Prospective, randomized comparison of epidural versus parenteral opioid analgesia in thoracic trauma. Ann Surg. 1999;229:684–91.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  180. Galvagno SM, Smith CE, Varon AJ, et al. Pain management for blunt thoracic trauma: a joint practice management guideline from the Eastern Association for the Surgery of Trauma and Trauma Anesthesiology Society. J Trauma Acute Care Surg. 2016;81(5):936–51.

    Article  PubMed  Google Scholar 

  181. Malekpour M, Hashmi A, Dove J, Torres D, Wild J. Analgesic choice in management of rib fractures: paravertebral block or epidural analgesia? Anesth Analg. 2017;124:1906–11.

    Article  CAS  PubMed  Google Scholar 

  182. Unsworth A, Curtis K, Asha SE. Treatments for blunt chest trauma and their impact on patient outcomes and health service delivery. Scand J Trauma Resusc Emerg Med. 2015;23:17.

    Article  PubMed  PubMed Central  Google Scholar 

  183. Monaghan SF, Adams CA, Connolly MD, Stephen AH, Lueckel SN, Harrington DT, Cioffi WG, Heffernan DS. A geriatric specific rib fracture protocol significantly improves mortality. Oral presentation as part of the 73rd annual meeting of the American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery, Philadelphia, 10–13 Sept 2014.

    Google Scholar 

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Clinical Case Discussion

Case Pt is a 27-year-old male who was stabbed at the base of the neck and thrown off the top of a three-story building. He arrives in the emergency room intoxicated but awake and alert. He is hemodynamically stable. His past medical history is noncontributory. He is extremely tachypnic, anxious, and complaining of shortness of breath. He is coughing up a small amount of blood. He is wearing a cervical collar. On secondary survey he is found to have subcutaneous emphysema.

Questions

  1. 1.

    What are the anesthesiologists concerns?

  2. 2.

    Should any further imaging be obtained prior to intubation?

  3. 3.

    What airway device should be placed?

  4. 4.

    What technique should be used to intubate the patient?

Given the mechanism of injury and the presence of subcutaneous emphysema and hemoptysis, the anesthesiologist should be concerned that there is an injury to the airway. While under ideal conditions an awake fiberoptic intubation would be preferred, the scenario presented describes a patient who is in respiratory distress and could not be expected to participate in an awake fiberoptic intubation. No further imaging should be necessary in this patient who clearly needs urgent control of the airway. Rapid sequence intubation with in-line stabilization remains the standard of care and should be performed without delay. Strict attention should be made to the patient’s hemodynamics after intubation, since converting a presumed pneumothorax to a tension pneumothorax is possible in this scenario. Every attempt must be made to place the endotracheal tube with great care in an effort not to disrupt a potential injury to the trachea.

Scenario continues: The patient is successfully intubated, and a chest tube is placed for decreased breath sounds over the right chest. A large air leak is found. The following CXR is obtained.

Fig. 51.12

Chest X-ray shows a patient with a persistent right pneumothorax despite a well-positioned thoracotomy tube and an endotracheal tube above the carina

Questions

  1. 1.

    What would be the next step in the evaluation of this patient?

  2. 2.

    How can the anesthesiologist manage the air leak?

  3. 3.

    The patient is being taken to the operating room for surgical repair. What form of lung isolation should be used?

Fig. 51.13

Computed tomography scan demonstrating posterior tracheal tear, subcutaneous emphysema and persistent right pneumothorax. Subcutaneous emphysema is also demonstrated

Fig. 51.14

Intraoperative view of posterior tracheal injury seen through a right thoracotomy. (Photo courtesy of Thomas NG, MD, thoracic surgery, Rhode Island Hospital)

Questions

  • Would you extubate this patient at the end of the case?

  • How would you control his pain from the rib fractures?

These are both difficult questions. In general, every effort to extubate the patient as soon as possible should be made given his tracheal repair. Managing the pain of his rib fractures may be difficult. If he is awake and cooperative post extubation, an epidural can be considered. If not, paravertebral blocks or a catheter may be an option since the rib fractures are unilateral.

Electronic Supplementary Material

A mid-esophageal four-chamber view showing a right ventricular contusion with severe right ventricular hypokinesis (MOV 28601 kb)

A mid-esophageal right ventricular inflow-outflow view showing a tricuspid valve injury (MOV 16652 kb)

Color Doppler demonstrating severe tricuspid regurgitation associated with a traumatic tricuspid valve injury (MOV 7771 kb)

A large traumatic pericardial effusion with right atrial systolic collapse, suggesting pericardial tamponade (MOV 16623 kb)

A large traumatic pericardial effusion with right ventricular diastolic collapse, suggesting pericardial tamponade (MP4 976 kb)

A view of the descending thoracic aorta demonstrating a traumatic aortic dissection with a thin intimal flap dividing the aorta into true and false lumens (MP4 873 kb)

A view of the descending thoracic aorta with a “medial flap” demonstrating traumatic aortic disruption (MOV 43659 kb)

A transgastric left ventricular short axis view showing severe hypovolemia (MP4 873 kb)

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Panaro, S.V., Chen, T.H. (2019). Anesthetic Management of Thoracic Trauma. In: Slinger, P. (eds) Principles and Practice of Anesthesia for Thoracic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-00859-8_51

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