Skip to main content

Abstract

Diagnostic flexible bronchoscopy is safely performed outside of the operating room with light to moderate sedation and topical anesthesia. Rigid bronchoscopy is typically performed in patients with central airway obstruction and major comorbidities. Primary concerns include the risk of complete airway obstruction and inability to ventilate or dynamic hyperventilation with hemodynamic compromise. A fluid transition between ventilation strategies is often required for these procedures. Extracorporeal membrane oxygenation may be implemented when conventional approaches are not feasible or deemed safe. Multimodal techniques employed by interventional bronchoscopists to acutely re-establish patency of obstructed central airways include stenting, laser, endobronchial electrosurgery, argon plasma coagulation, and balloon bronchoplasty. Major intraoperative complications associated with these techniques include hemorrhage, airway trauma, perforation, fire, systemic gas embolism, and dissemination of postobstructive pneumonia. Alternative indications for these procedures include treatment of low-grade malignancies and carcinoma in situ. These lesions may also respond to brachytherapy, cryotherapy, or photodynamic therapy. Interventional bronchoscopy is an evolving field with expanding applications with both diagnostic and therapeutic modalities covering benign and malignant pulmonary disease. Future indications may include endobronchial valve insertion for persistent air leaks and lung volume reduction in COPD as well as bronchial thermoplasty for treatment-resistant asthma.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Limper AH, Prakash UB. Tracheobronchial foreign bodies in adults. Ann Intern Med. 1990;112(8):604–9.

    Article  CAS  PubMed  Google Scholar 

  2. Conacher ID, Curran E. Local anaesthesia and sedation for rigid bronchoscopy for emergency relief of central airway obstruction. Anaesthesia. 2004;59(3):290–2.

    Article  CAS  PubMed  Google Scholar 

  3. Chadha M, Kulshrestha M, Biyani A. Anaesthesia for bronchoscopy. Indian J Anaesth. 2015;59(9):565–73.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Ernst A, Simoff M, Ost D, Goldman Y, Herth FJ. Prospective risk-adjusted morbidity and mortality outcome analysis after therapeutic bronchoscopic procedures: results of a multi-institutional outcomes database. Chest. 2008;134(3):514–9.

    Article  PubMed  Google Scholar 

  5. Perrin G, Colt HG, Martin C, Mak MA, Dumon JF, Gouin F. Safety of interventional rigid bronchoscopy using intravenous anesthesia and spontaneous assisted ventilation. A prospective study. Chest. 1992;102(5):1526–30.

    Article  CAS  PubMed  Google Scholar 

  6. Metzner J, Posner KL, Domino KB. The risk and safety of anesthesia at remote locations: the US closed claims analysis. Curr Opin Anaesthesiol. 2009;22(4):502–8.

    Article  PubMed  Google Scholar 

  7. Folch E, Mehta AC. Airway interventions in the tracheobronchial tree. Semin Respir Crit Care Med. 2008;29(4):441–52.

    Article  PubMed  Google Scholar 

  8. Brodsky JB. Bronchoscopic procedures for central airway obstruction. J Cardiothorac Vasc Anesth. 2003;17(5):638–46.

    Article  PubMed  Google Scholar 

  9. Pinsonneault C, Fortier J, Donati F. Tracheal resection and reconstruction. Can J Anaesth. 1999;46(5):439–55.

    Article  CAS  PubMed  Google Scholar 

  10. Mason RA, Fielder CP. The obstructed airway in head and neck surgery. Anaesthesia. 1999;120(4):1152–6.

    Google Scholar 

  11. Hnatiuk OW, Corcoran PC, Sierra A. Spirometry in surgery for anterior mediastinal masses. Chest. 2001;120(4):1152–6.

    Article  CAS  PubMed  Google Scholar 

  12. Ernst A, Feller-Kopman D, Becker HD, Mehta AC. Central airway obstruction. Am J Respir Crit Care Med. 2004;169(12):1278–97.

    Article  PubMed  Google Scholar 

  13. Walser EM. Stent placement for tracheobronchial disease. Eur J Radiol. 2005;55(3):321–30.

    Article  PubMed  Google Scholar 

  14. Lee KS, Lunn W, Feller-Kopman D, Ernst A, Hatabu H, Boiselle PM. Multislice CT evaluation of airway stents. J Thorac Imaging. 2005;20(2):81–8.

    Article  PubMed  Google Scholar 

  15. Burke AJ, Vining DJ, McGuirt WF, Postma G, Browne JD. Evaluation of airway obstruction using virtual endoscopy. Laryngoscope. 2000;110(1):23–9.

    Article  CAS  PubMed  Google Scholar 

  16. Baroni RH, Ashiku S, Boiselle PM. Dynamic CT evaluation of the central airways in patients undergoing tracheoplasty for tracheobronchomalacia. Am J Roentgenol. 2005;184(5):1444–9.

    Article  Google Scholar 

  17. Conacher ID. Anaesthesia and tracheobronchial stenting for central airway obstruction in adults. Br J Anaesth. 2003;90(3):367–74.

    Article  CAS  PubMed  Google Scholar 

  18. Wood D. Airway stenting. Chest Surg Clin N Am. 2003;13(2):211–29.

    Article  PubMed  Google Scholar 

  19. Ho AM, Dion PW, Karmakar MK, Chung DC, Tay BA. Use of heliox in critical upper airway obstruction. Physical and physiologic considerations in choosing the optimal helium:Oxygen mix. Resuscitation. 2002;52(3):297–300.

    Article  PubMed  Google Scholar 

  20. Stephens KE, Wood DE. Bronchoscopic management of central airway obstruction. J Thorac Cardiovasc Surg. 2000;119(2):289–96.

    Article  PubMed  Google Scholar 

  21. Vonk-Noordegraaf A, Postmus PE, Sutedja TG. Tracheobronchial stenting in the terminal care of cancer patients with central airways obstruction. Chest. 2001;120(6):1811–4.

    Article  CAS  PubMed  Google Scholar 

  22. Hautmann H, Gamarra F, Henke M, Diehm S, Huber RM. High frequency jet ventilation in interventional fiberoptic bronchoscopy. Anesth Analg. 2000;90(6):1436–40.

    Article  CAS  PubMed  Google Scholar 

  23. Smith IJ, Sidebotham DA, McGeorge AD, Dorman EB, Wilsher ML, Kolbe J. Use of extracorporeal membrane oxygenation during resection of tracheal papillomatosis. Anesthesiology. 2009;110(2):427–9.

    PubMed  Google Scholar 

  24. Zhou YF, Zhu SJ, Zhu SM, An XX. Anesthetic management of emergent critical tracheal stenosis. J Zhejiang Univ Sci B. 2007;8(7):522–5.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Vourc'h G, Fischler M, Michon F, Melchior JC, Seigneur F. Manual jet ventilation v. high frequency jet ventilation during laser resection of tracheo-bronchial stenosis. Br J Anaesth. 1983;55(10):973–5.

    Article  CAS  PubMed  Google Scholar 

  26. Vaitkeviciute I, Ehrenwerth J. Con: bronchial stenting and laser airway surgery should not take place outside the operating room. J Cardiothorac Vasc Anesth. 2005;19(1):121–2.

    Article  PubMed  Google Scholar 

  27. Wahidi MM, Herth FJ, Ernst A. State of the art: interventional pulmonology. Chest. 2007;131(1):261–74.

    Article  PubMed  Google Scholar 

  28. Barbaro RP, Odetola FO, Kidwell KM, Paden ML, Bartlett RH, Davis MM, Annich GM. Association of hospital-level volume of extracorporeal membrane oxygenation cases and mortality. Analysis of the extracorporeal life support organization registry. Am J Respir Crit Care Med. 2015;191(8):894–901.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Kim CW, Kim DH, Son BS, Cho JS, Kim YD, Hoseok I, Ahn HY. The feasibility of extracorporeal membrane oxygenation in the variant airway problems. Ann Thorac Cardiovasc Surg. 2015;21(6):517–22.

    Article  PubMed  PubMed Central  Google Scholar 

  30. McLenon M, Bittle GJ, Jones K, Menaker J, Pham SM, Iacono AT, et al. Extracorporeal lung support as a bridge to airway stenting and radiotherapy for airway-obstructing pancoast tumor. Ann Thorac Surg. 2016;102(1):e7–9.

    Article  PubMed  Google Scholar 

  31. Willms DC, Mendez R, Norman V, Chammas JH. Emergency bedside extracorporeal membrane oxygenation for rescue of acute tracheal obstruction. Respir Care. 2012;57(4):646–9.

    Article  PubMed  Google Scholar 

  32. Ko M, dos Santos PR, Machuca TN, Marseu K, Waddell TK, Keshavjee S, Cypel M. Use of single-cannula venous-venous extracorporeal life support in the management of life-threatening airway obstruction. Ann Thorac Surg. 2015;99(3):e63–5.

    Article  PubMed  Google Scholar 

  33. Natt B, Knepler J Jr, Kazui T, Mosier JM. The use of extracorporeal membrane oxygenation in the bronchoscopic management of critical upper airway obstruction. J Bronchol Interv Pulmonol. 2017;24(1):e12–4.

    Article  Google Scholar 

  34. Hong Y, Jo KW, Lyu J, Huh JW, Hong SB, Jung SH, et al. Use of venovenous extracorporeal membrane oxygenation in central airway obstruction to facilitate interventions leading to definitive airway security. J Crit Care. 2013;28(5):669–74.

    Article  PubMed  Google Scholar 

  35. Guha A, Mostafa SM, Kendall JB. The montgomery t-tube: Anaesthetic problems and solutions. Br J Anaesth. 2001;87(5):787–90.

    Article  CAS  PubMed  Google Scholar 

  36. Dumon JF. A dedicated tracheobronchial stent. Chest. 1990;97(2):328–32.

    Article  CAS  PubMed  Google Scholar 

  37. Saito Y. Endobronchial stents: past, present, and future. Semin Respir Crit Care Med. 2004;25(4):375–80.

    Article  PubMed  Google Scholar 

  38. Stehlik L, Hytych V, Letackova J, Kubena P, Vasakova M. Biodegradable polydioxanone stents in the treatment of adult patients with tracheal narrowing. BMC Pulm Med. 2015;15:164.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  39. Finlayson GN, Brodsky JB. Anesthetic considerations for airway stenting in adult patients. Anesthesiol Clin. 2008;26(2):281–91.

    Article  PubMed  Google Scholar 

  40. Zakaluzny SA, Lane JD, Mair EA. Complications of tracheobronchial airway stents. Otolaryngol Head Neck Surg. 2003;128(4):478–88.

    Article  PubMed  Google Scholar 

  41. Bolliger CT, Sutedja TG, Strausz J, Freitag L. Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents. Eur Respir J. 2006;27(6):1258–71.

    Article  CAS  PubMed  Google Scholar 

  42. Grillo HC. Stents and sense. Ann Thorac Surg. 2000;70(4):1142.

    Article  CAS  PubMed  Google Scholar 

  43. Grewe PH, Müller KM, Lindstaedt M, Germing A, Müller A, Mügge A, Deneke T. Reaction patterns of the tracheobronchial wall to implanted noncovered metal stents. Chest. 2005;128(2):986–90.

    Article  PubMed  Google Scholar 

  44. Thornton RH, Gordon RL, Kerlan RK, LaBerge JM, Wilson MW, Wolanske KA, et al. Outcomes of tracheobronchial stent placement for benign disease 1. Radiology. 2006;240(1):273–82.

    Article  PubMed  Google Scholar 

  45. Eller RL, Livingston WJ, Morgan CE, Peters GE, Sillers MJ, Magnuson JS, Rosenthal EL. Expandable tracheal stenting for benign disease: worth the complications? Ann Otol Rhinol Laryngol. 2006;115(4):247–52.

    Article  PubMed  Google Scholar 

  46. Makris D, Marquette CH. Tracheobronchial stenting and central airway replacement. Curr Opin Pulm Med. 2007;13(4):278–83.

    Article  PubMed  Google Scholar 

  47. Urschel JD. Delayed massive hemoptysis after expandable bronchial stent placement. J Laparoendosc Adv Surg Tech A. 1999;9(2):155–8.

    Article  CAS  PubMed  Google Scholar 

  48. Hung WT, Liao SM, Su JM. Laryngeal mask airway in patients with tracheal stents who are undergoing non-airway related interventions: report of three cases. J Clin Anesth. 2004;16(3):214–6.

    Article  PubMed  Google Scholar 

  49. Davis N, Madden BP, Sheth A, Crerar-Gilbert AJ. Airway management of patients with tracheobronchial stents. Br J Anaesth. 2006;96(1):132–5.

    Article  CAS  PubMed  Google Scholar 

  50. Yan Y, Olszewski AE, Hoffman MR, Zhuang P, Ford CN, Dailey SH, Jiang JJ. Use of lasers in laryngeal surgery. J Voice. 2010;24(1):102–9.

    Article  PubMed  Google Scholar 

  51. Van Der Spek AF, Spargo PM, Norton ML. The physics of lasers and implications for their use during airway surgery. Br J Anaesth. 1988;60(6):709–29.

    Article  Google Scholar 

  52. Cortese DA. Rigid versus flexible bronchoscope in laser bronchoscopy pro rigid bronchoscopic laser application. J Bronchol Interv Pulmonol. 1994;1(1):72–5.

    Google Scholar 

  53. Moghissi K, Dixon K, Hudson E, Stringer M, Brown S. Endoscopic laser therapy in malignant tracheobronchial obstruction using sequential nd YAG laser and photodynamic therapy. Thorax. 1997;52(3):281–3.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  54. Geffin B, Shapshay SM, Bellack GS, Hobin K, Setzer SE. Flammability of endotracheal tubes during nd-yag laser application in the airway. Anesthesiology. 1986;65(5):511–5.

    Article  CAS  PubMed  Google Scholar 

  55. Lee P, Kupeli E, Mehta AC. Therapeutic bronchoscopy in lung cancer. Laser therapy, electrocautery, brachytherapy, stents, and photodynamic therapy. Clin Chest Med. 2002;23(1):241–56.

    Article  PubMed  Google Scholar 

  56. Tellides G, Ugurlu BS, Kim RW, Hammond GL. Pathogenesis of systemic air embolism during bronchoscopic nd:YAG laser operations. Ann Thorac Surg. 1998;65(4):930–4.

    Article  CAS  PubMed  Google Scholar 

  57. Lobraico RV, Schifano MJ, Brader KR. A retrospective study on the hazards of the carbon dioxide laser plume. J Laser Appl. 1988;1(1):6–8.

    Article  Google Scholar 

  58. Garden JM, O'Banion MK, Shelnitz LS, Pinski KS, Bakus AD, Reichmann ME, Sundberg JP. Papillomavirus in the vapor of carbon dioxide laser-treated verrucae. JAMA. 1988;259(8):1199–202.

    Article  CAS  PubMed  Google Scholar 

  59. Baggish MS, Poiesz BJ, Joret D, Williamson P, Refai A. Presence of human immunodeficiency virus DNA in laser smoke. Lasers Surg Med. 1991;11(3):197–203.

    Article  CAS  PubMed  Google Scholar 

  60. Barlow DE. Endoscopic applications of electrosurgery: a review of basic principles. Gastrointest Endosc. 1982;28(2):73–6.

    Article  CAS  PubMed  Google Scholar 

  61. Coulter TD, Mehta AC. The heat is on: impact of endobronchial electrosurgery on the need for nd-yag laser photoresection. Chest. 2000;118(2):516–21.

    Article  CAS  PubMed  Google Scholar 

  62. Boxem TV, Muller M, Venmans B, Postmus P, Sutedja T. Nd-YAG laser vs bronchoscopic electrocautery for palliation of symptomatic airway obstruction: a cost-effectiveness study. Chest. 1999;116(4):1108–12.

    Article  CAS  PubMed  Google Scholar 

  63. Ernst A, Silvestri GA, Johnstone D. Interventional pulmonary procedures: guidelines from the american college of chest physicians. Chest J. 2003;123(5):1693–717.

    Article  Google Scholar 

  64. Grund KE, Storek D, Farin G. Endoscopic argon plasma coagulation (APC) first clinical experiences in flexible endoscopy. Endosc Surg Allied Technol. 1994;2(1):42–6.

    CAS  PubMed  Google Scholar 

  65. Sheski FD, Mathur PN. Endobronchial electrosurgery: argon plasma coagulation and electrocautery. Semin Respir Crit Care Med. 2004;25(4):367–74.

    Article  PubMed  Google Scholar 

  66. Morice RC, Ece T, Ece F, Keus L. Endobronchial argon plasma coagulation for treatment of hemoptysis and neoplastic airway obstruction. Chest. 2001;119(3):781–7.

    Article  CAS  PubMed  Google Scholar 

  67. Reddy C, Majid A, Michaud G, Feller-Kopman D, Eberhardt R, Herth F, Ernst A. Gas embolism following bronchoscopic argon plasma coagulation: a case series. Chest. 2008;134(5):1066–9.

    Article  PubMed  Google Scholar 

  68. McArdle JR, Gildea TR, Mehta AC. Balloon bronchoplasty: its indications, benefits, and complications. J Bronchol Interv Pulmonol. 2005;12(2):123–7.

    Google Scholar 

  69. Vergnon JM, Huber RM, Moghissi K. Place of cryotherapy, brachytherapy and photodynamic therapy in therapeutic bronchoscopy of lung cancers. Eur Respir J. 2006;28(1):200–18.

    Article  PubMed  Google Scholar 

  70. Schumann C, Hetzel M, Babiak AJ, Hetzel J, Merk T, Wibmer T, et al. Endobronchial tumor debulking with a flexible cryoprobe for immediate treatment of malignant stenosis. J Thorac Cardiovasc Surg. 2010;139(4):997–1000.

    Article  PubMed  Google Scholar 

  71. Mohamed AS, El-Din MAA. Fiberoptic bronchoscopic cryo-ablation of central bronchial lung cancer. Egypt J Chest Dis Tuberc. 2016;65(2):527–30.

    Article  Google Scholar 

  72. Inaty H, Folch E, Berger R, Fernandez-Bussy S, Chatterji S, Alape D, Majid A. Unimodality and multimodality cryodebridement for airway obstruction. A single-center experience with safety and efficacy. Ann Am Thorac Soc. 2016;13(6):856–61.

    Article  PubMed  Google Scholar 

  73. Browning R, Parrish S, Sarkar S, Turner JF. First report of a novel liquid nitrogen adjustable flow spray cryotherapy (SCT) device in the bronchoscopic treatment of disease of the central tracheo-bronchial airways. J Thorac Dis. 2013;5(3):E103–6.

    PubMed  PubMed Central  Google Scholar 

  74. Browning R, Turner JF, Parrish S. Spray cryotherapy (SCT): institutional evolution of techniques and clinical practice from early experience in the treatment of malignant airway disease. J Thorac Dis. 2015;7(Suppl 4):S405–14.

    PubMed  PubMed Central  Google Scholar 

  75. Rafanan AL, Mehta AC. Adult airway foreign body removal. What’s new? Clin Chest Med. 2001;22(2):319–30.

    Article  CAS  PubMed  Google Scholar 

  76. Swanson KL. Airway foreign bodies: What’s new? Semin Respir Crit Care Med. 2004;25(4):405–11.

    Article  PubMed  Google Scholar 

  77. Zur KB, Litman RS. Pediatric airway foreign body retrieval: surgical and anesthetic perspectives. Paediatr Anaesth. 2009;19(Suppl 1):109–17.

    Article  PubMed  Google Scholar 

  78. McKenna RJ. Endobronchial valves for the treatment of emphysema. Semin Thorac Cardiovasc Surg. 2008;20(4):285–9.

    Article  PubMed  Google Scholar 

  79. Valipour A, Slebos DJ, Herth F, Darwiche K, Wagner M, Ficker JH, et al. Endobronchial valve therapy in patients with homogeneous emphysema. Results from the IMPACT study. Am J Respir Crit Care Med. 2016;194(9):1073–82.

    Article  PubMed  Google Scholar 

  80. Hopkinson NS. Bronchoscopic lung volume reduction: indications, effects and prospects. Curr Opin Pulm Med. 2007, Mar;13(2):125–30.

    Article  PubMed  Google Scholar 

  81. Sciurba FC, Ernst A, Herth FJ, Strange C, Criner GJ, Marquette CH, et al. A randomized study of endobronchial valves for advanced emphysema. N Engl J Med. 2010, Sep 23;363(13):1233–44.

    Article  CAS  PubMed  Google Scholar 

  82. Klooster K, ten Hacken NH, Hartman JE, Kerstjens HA, van Rikxoort EM, Slebos D-J. Endobronchial valves for emphysema without interlobar collateral ventilation. N Engl J Med. 2015;373(24):2325–35.

    Article  CAS  PubMed  Google Scholar 

  83. Sciurba FC, Criner GJ, Strange C, Shah PL, Michaud G, Connolly TA, et al. Effect of endobronchial coils vs usual care on exercise tolerance in patients with severe emphysema: the RENEW randomized clinical trial. JAMA. 2016;315(20):2178–89.

    Article  CAS  PubMed  Google Scholar 

  84. Deslée G, Mal H, Dutau H, Bourdin A, Vergnon JM, Pison C, et al. Lung volume reduction coil treatment vs usual care in patients with severe emphysema: the REVOLENS randomized clinical trial. JAMA. 2016;315(2):175–84.

    Article  PubMed  CAS  Google Scholar 

  85. Travaline JM, McKenna RJ, De Giacomo T, Venuta F, Hazelrigg SR, Boomer M, et al. Treatment of persistent pulmonary air leaks using endobronchial valves. Chest. 2009;136(2):355–60.

    Article  PubMed  Google Scholar 

  86. Ingenito EP, Wood DE, Utz JP. Bronchoscopic lung volume reduction in severe emphysema. Proc Am Thorac Soc. 2008;5(4):454–60.

    Article  PubMed  PubMed Central  Google Scholar 

  87. Shah PL, Slebos DJ, Cardoso PF, Cetti E, Voelker K, Levine B, et al. Bronchoscopic lung-volume reduction with exhale airway stents for emphysema (EASE trial): randomised, sham-controlled, multicentre trial. Lancet. 2011;378(9795):997–1005.

    Article  CAS  PubMed  Google Scholar 

  88. Bel EH. “Hot Stuff” bronchial thermoplasty for asthma. Am J Respir Crit Care Med. 2006;173:941–2.

    Article  PubMed  Google Scholar 

  89. Cox G. New interventions in asthma including bronchial thermoplasty. Curr Opin Pulm Med. 2008;14(1):77–81.

    Article  PubMed  Google Scholar 

  90. Lee P, Mehta AC, Mathur PN. Management of complications from diagnostic and interventional bronchoscopy. Respirology. 2009;14(7):940–53.

    Article  PubMed  Google Scholar 

  91. Burns DM, Shure D, Francoz R, Kalafer M, Harrell J, Witztum K, Moser KM. The physiologic consequences of saline lobar lavage in healthy human adults. Am Rev Respir Dis. 1983;127(6):695–701.

    CAS  PubMed  Google Scholar 

  92. Hariri LP, Applegate MB, Mino-Kenudson M, Mark EJ, Bouma BE, Tearney GJ, Suter MJ. Optical frequency domain imaging of ex vivo pulmonary resection specimens: obtaining one to one image to histopathology correlation. J Vis Exp. 2013;71:e3855.

    Google Scholar 

  93. Hariri LP, Mino-Kenudson M, Applegate MB, Mark EJ, Tearney GJ, Lanuti M, et al. Toward the guidance of transbronchial biopsy: identifying pulmonary nodules with optical coherence tomography. Chest. 2013;144(4):1261–8.

    Article  PubMed  PubMed Central  Google Scholar 

  94. Strumpf IJ, Feld MK, Cornelius MJ, Keogh BA, Crystal RG. Safety of fiberoptic bronchoalveolar lavage in evaluation of interstitial lung disease. Chest. 1981;80(3):268–71.

    Article  CAS  PubMed  Google Scholar 

  95. Pingleton SK, Harrison GF, Stechschulte DJ, Wesselius LJ, Kerby GR, Ruth WE. Effect of location, ph, and temperature of instillate in bronchoalveolar lavage in normal volunteers. Am Rev Respir Dis. 1983;128(6):1035–7.

    CAS  PubMed  Google Scholar 

  96. Wardlaw AJ, Collins JV, Kay AB. Mechanisms in asthma using the technique of bronchoalveolar lavage. Int Arch Allergy Appl Immunol. 1987;82(3–4):518–25.

    Article  CAS  PubMed  Google Scholar 

  97. Klech H, Pohl W. Technical recommendations and guidelines for bronchoalveolar lavage (BAL). Eur Respir J. 1989;2(6):561–85.

    Google Scholar 

  98. Schreiber G, McCrory DC. Performance characteristics of different modalities for diagnosis of suspected lung cancer: summary of published evidence. Chest. 2003;123:115S–28S.

    Article  PubMed  Google Scholar 

  99. Colt HG, Prakash UB, Offord KP. Bronchoscopy in north america: survey by the american association for bronchology, 1999. J Bronchol Interv Pulmonol. 2000;7(1):8–25.

    Google Scholar 

  100. Sheski FD, Mathur PN. Endobronchial ultrasound. Chest. 2008;133(1):264–70.

    Article  PubMed  Google Scholar 

  101. Krasnik M, Vilmann P, Larsen SS, Jacobsen GK. Preliminary experience with a new method of endoscopic transbronchial real time ultrasound guided biopsy for diagnosis of mediastinal and hilar lesions. Thorax. 2003;58(12):1083–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  102. Herth FJ, Lunn W, Eberhardt R, Becker HD, Ernst A. Transbronchial versus transesophageal ultrasound-guided aspiration of enlarged mediastinal lymph nodes. Am J Respir Crit Care Med. 2005;171(10):1164–7.

    Article  PubMed  Google Scholar 

  103. Kennedy MP, Jimenez CA, Morice RC, Eapen GA. Ultrasound-guided endobronchial, endoscopic, and transthoracic biopsy. Semin Respir Crit Care Med. 2008;29(4):453–64.

    Article  PubMed  Google Scholar 

  104. Kucera F, Wolfe GK, Perry ME. Hemomediastinum after transbronchial needle aspiration. Chest. 1990;3:466.

    Google Scholar 

  105. Epstein SK, Winslow CJ, Brecher SM, Faling LJ. Polymicrobial bacterial pericarditis after transbronchial needle aspiration. Case report with an investigation on the risk of bacterial contamination during fiberoptic bronchoscopy. Am Rev Respir Dis. 1992;146(2):523–5.

    Article  CAS  PubMed  Google Scholar 

  106. Simpson FG, Arnold AG, Purvis A, Belfield PW, Muers MF, Cooke NJ. Postal survey of bronchoscopic practice by physicians in the United Kingdom. Thorax. 1986;41(4):311–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  107. Ernst A, Eberhardt R, Wahidi M, Becker HD, Herth FJ. Effect of routine clopidogrel use on bleeding complications after transbronchial biopsy in humans. Chest. 2006;129(3):734–7.

    Article  PubMed  Google Scholar 

  108. Papin TA, Grum CM, Weg JG. Transbronchial biopsy during mechanical ventilation. Chest. 1986;89(2):168–70.

    Article  CAS  PubMed  Google Scholar 

  109. O'Brien JD, Ettinger NA, Shevlin D, Kollef MH. Safety and yield of transbronchial biopsy in mechanically ventilated patients. Crit Care Med. 1997;25(3):440–6.

    Article  CAS  PubMed  Google Scholar 

  110. Rose DD. Review of anticholinergic drugs: their use and safe omittance in preoperative medications. AANA J. 1984.

    Google Scholar 

  111. Corallo CE, Whitfield A, Wu A. Anticholinergic syndrome following an unintentional overdose of scopolamine. Ther Clin Risk Manag. 2009;5(5):719–23.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  112. Simmons ST, Schleich AR. Airway regional anesthesia for awake fiberoptic intubation. Reg Anesth Pain Med. 2002;27(2):180–92.

    PubMed  Google Scholar 

  113. Kundra P, Kutralam S, Ravishankar M. Local anaesthesia for awake fibreoptic nasotracheal intubation. Acta Anaesthesiol Scand. 2000;44(5):511–6.

    Article  CAS  PubMed  Google Scholar 

  114. Mostafa SM, Murthy BVS, Hodgson CA, Beese E. Nebulized 10% lignocaine for awake fibreoptic intubation. Anaesth Intensive Care. 1998;26(2):222.

    CAS  PubMed  Google Scholar 

  115. Chung DC, Mainland PA, Kong AS. Anesthesia of the airway by aspiration of lidocaine. Can J Anaesth. 1999;46(3):215–9.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gordon N. Finlayson .

Editor information

Editors and Affiliations

Clinical Case Discussion

Clinical Case Discussion

A 65-year-old woman with a remote transhiatal esophagectomy for cancer presented with 2 days of increasing dyspnea. She remains hypoxemic following intubation for respiratory failure in the emergency department, despite maximal conventional ventilation. CT imaging demonstrates near-complete obstruction of the left main bronchus and significant obstruction of the right main bronchus (Fig. 11.11). The Interventional Pulmonologist intends to perform balloon dilatation, tumor resection, and stent insertion in the left main bronchus via rigid bronchoscopy.

Fig. 11.11
figure 11figure 11

(a) Bronchoscopic picture of the right bronchus intermediate (RBI) stenosis and left main bronchial stenosis (Lt main); CT scan of the chest demonstrates near occlusion of the left main airway by tumor. (b) Balloon dilation of the left main bronchus (left). Fluoroscopy image shows stent insertion via rigid bronchoscopy (right) (c) Bronchoscopic examination shows left main airway stent and patent right main airway post balloon dilation and stent placement

Questions

Outline the considerations of providing anesthesia for patients with central airway obstruction:

  • Risk of complete airway obstruction and impossible ventilation

  • Potential for dynamic hyperinflation resulting in hemodynamic compromise or barotrauma

  • Considerations and complications of rigid and interventional bronchoscopy

Describe the ventilation techniques applied during rigid bronchoscopy:

  • Spontaneous

  • Assisted

  • Sanders jet ventilation

  • HFJV

Describe the acute complications of balloon bronchoplasty, airway stenting, and electrocautery:

  • Tracheitis

  • Fever

  • Atelectasis

  • Bronchospasm

  • Airway disruption

  • Dissemination of obstructing pneumonia

  • Hemorrhage

  • Airway fire

  • Electromagnetic interference

Authors’ Management

General anesthesia was maintained by TIVA and neuromuscular blockade. Fiber-optic inspection of the tracheobronchial tree was expeditiously performed to further evaluate the tumor and characterize the anatomy of the obstruction. Given the degree of hypoxemia, an exchange catheter was inserted adjacent to the endotracheal tube, to allow for temporary oxygenation during the transition between tracheal extubation and access with the rigid bronchoscope. Ventilation following tracheal placement of the rigid bronchoscope was supported with a Sanders jet injector. Left mainstem patency was re-established using a combination of balloon dilation, electrocautery, and stent placement. Following restoration of normal gas exchange, balloon dilation of the right mainstem was employed, the trachea was extubated, and a laryngeal mask was inserted. Once the patient recovered from intravenous anesthesia, neuromuscular blockade was reversed, adequate spontaneous ventilation was established, and the patient was observed in the operating room until fully awake (Fig. 11.11).

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Finlayson, G.N., Shaipanich, T., Durkin, C. (2019). Bronchoscopic Procedures. In: Slinger, P. (eds) Principles and Practice of Anesthesia for Thoracic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-00859-8_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-00859-8_11

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-00858-1

  • Online ISBN: 978-3-030-00859-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics