Abstract
One form of amyloidosis, β2-microglobulin, is characteristic in renal dialysis patients. Amyloid is deposited in the skeleton and periosteal tissues and is a further manifestation of renal bone disease. About 200 mg of this protein are produced each day on cell surfaces, normally filtered by the glomeruli and catabolised in the tubuli. However, this low-molecular-weight protein does not filter well through dialysis membranes and as a consequence accumulates in tissues. After 10 or more years of dialysis, about 70% of patients are affected.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Bartl, R., Bartl, C. (2019). Haemodialysis-Associated Amyloidosis. In: The Osteoporosis Manual. Springer, Cham. https://doi.org/10.1007/978-3-030-00731-7_90
Download citation
DOI: https://doi.org/10.1007/978-3-030-00731-7_90
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-00730-0
Online ISBN: 978-3-030-00731-7
eBook Packages: MedicineMedicine (R0)