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Omics Approaches to Understanding Muscle Biology pp 1–6Cite as

The Role of Omics Approaches in Muscle Research

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Part of the book series: Methods in Physiology ((METHPHYS))

Abstract

A thorough understanding of skeletal muscle physiology requires knowledge of the molecular composition of muscle tissue. So far, this has been mostly obtained through biochemical investigations focused on selected components of the muscle contractile and metabolic machinery. More recently, a systems biology approach, based on the emergence of omics technologies, has been introduced to get global views of all muscle components. These approaches have been used to explore the DNA (genomics and epigenomics), RNA (transcriptomics and non-coding RNA analyses), proteins (proteomics and global analyses of post-translational protein modifications, e.g. phosphoproteomics) and small molecules (metabolomics).

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Author information

Authors and Affiliations

  1. Venetian Institute of Molecular Medicine (VIMM), Padova, Italy

    Stefano Schiaffino

  2. Department of Biomedical Sciences, University of Padova, Padova, Italy

    Carlo Reggiani & Marta Murgia

  3. Max-Planck-Institute of Biochemistry, Martinsried, Germany

    Marta Murgia

Authors
  1. Stefano Schiaffino
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  2. Carlo Reggiani
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  3. Marta Murgia
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Corresponding author

Correspondence to Stefano Schiaffino .

Editor information

Editors and Affiliations

  1. Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, Merseyside, UK

    Jatin George Burniston

  2. Children’s National Health System, George Washington University, Washington, DC, USA

    Yi-Wen Chen

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Schiaffino, S., Reggiani, C., Murgia, M. (2019). The Role of Omics Approaches in Muscle Research. In: Burniston, J., Chen, YW. (eds) Omics Approaches to Understanding Muscle Biology. Methods in Physiology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-9802-9_1

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