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Pathology of the Respiratory System

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Abstract

In this chapter, we will provide an overview of (1) the structure and function of the respiratory system, highlighting similarities and differences between humans and laboratory animals; (2) toxicant-induced pathology of the upper and lower respiratory tract, with site-specific examples and discussion of key mechanisms underlying toxicologic pathology of the lung; and (3) common and ancillary methods of analysis in respiratory toxicologic pathology. Our aim is to provide the non-pathologist with the fundamentals of respiratory pathology caused by toxic chemical agents.

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Correspondence to Jack R. Harkema .

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Harkema, J.R., Wagner, J.G. (2019). Pathology of the Respiratory System. In: Steinbach, T., Patrick, D., Cosenza, M. (eds) Toxicologic Pathology for Non-Pathologists. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9777-0_9

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