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The Adrenal Renin/Angiotensin System

  • Chapter
Tissue Renin-Angiotensin Systems

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 377))

Abstract

In mammals, the adrenals are paired glands lying anterior to the kidney, having a combined wet weight approximately 0.1%–0.2% of the total body weight. Histologically, the cells of the outer part of the gland, the cortex, which entirely surround the inner medulla, are arranged as three major layers, or zones, organized as concentric shells. These are the zonae glomerulosa, fasciculata and reticularis. The cells of the different zones are generally distinguished by their shape and size, as well as by their arrangement and disposition within the gland. In general, the cells of the glomerulosa, which lies beneath the connective tissue capsule, consists of an arrangment of cells variously described as loops, whorls or baskets. The larger, and more numerous, cells of the zona fasciculata are invariably arranged as centripetally oriented cords, which abut on to the less clearly organised network of cells which form the zona reticularis. The reticularis adjoins the central medulla (Vinson et al. 1992).

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Vinson, G.P. (1995). The Adrenal Renin/Angiotensin System. In: Mukhopadhyay, A.K., Raizada, M.K. (eds) Tissue Renin-Angiotensin Systems. Advances in Experimental Medicine and Biology, vol 377. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0952-7_14

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