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The Effect of Urinary Macromolecules on the Crystal Growth of Calcium Oxalate in Gel

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Urolithiasis

Abstract

Urinary macromolecules (for example, glycosaminoglycans, Tamm-Horsfall mucoprotein, and nephrocalcin) have long been supposed to affect crystal growth processes relevant in urinary stone formation (1, 2), However, data in the literature on this topic have been contradictory.

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References

  1. WG Robertson, DS Scurr, and VJ Sergeant, Ionic and macromolecular modifiers of crystallization of calcium salts in urine, Fortschr. Urol. Nephrol. 23: 1 (1985).

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  2. RL Ryall and VR Marshall, The relationship between urinary inhibitory activity and endogenous concentration of glycosaminoglycans and uric acid, Clin. Chim. Acta 141: 197 (1984).

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  3. W Achilles, Methodische neuerungen des kinetischen gelkristallisationsverfahrens (GKV): automatisierte messung des kalxiumoxalatkristallwachstums durch scanning-microskopphotometrie, Fortschr. Urol. Nephrol. 23: 252 (1985).

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  4. W Achilles, Kinetic quantification of crystal growth in gel matrices: an efficient model of urinary stone formation, in: this volume, p. 47.

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  5. W Achilles, C Schalk, E Krzyzanek, and D Coors, The effect of urinary constituents of low molecular weight on the crystal growth of calcium oxalate in gel, in: this volume, p. 219.

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  6. SD Roberts and MI Resnick, Glycosaminoglycans content of stone matrix, J. Urol. 135: 1078 (1986).

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Author information

Authors and Affiliations

  1. Urologie/Klin. Forschung, Universitätsklinikum Marburg, Marburg/Lahn, Germany

    W. Achilles, B. Reifenberger & C. Schalk

Authors
  1. W. Achilles
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  2. B. Reifenberger
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  3. C. Schalk
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Editor information

Editors and Affiliations

  1. University of British Columbia, Vancouver, British Columbia, Canada

    Valerie R. Walker , Roger A. L. Sutton  & E. C. Bert Cameron ,  & 

  2. Southwestern Medical Center, University of Texas, Dallas, Texas, USA

    Charles Y. C. Pak

  3. King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

    William G. Robertson

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© 1989 Springer Science+Business Media New York

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Achilles, W., Reifenberger, B., Schalk, C. (1989). The Effect of Urinary Macromolecules on the Crystal Growth of Calcium Oxalate in Gel. In: Walker, V.R., Sutton, R.A.L., Cameron, E.C.B., Pak, C.Y.C., Robertson, W.G. (eds) Urolithiasis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0873-5_21

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  • DOI: https://doi.org/10.1007/978-1-4899-0873-5_21

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0875-9

  • Online ISBN: 978-1-4899-0873-5

  • eBook Packages: Springer Book Archive

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